MMP16 as NSCL +/- P Susceptible Gene in Western Han Chinese. | MMP16 as NSCL ± P Susceptible Gene in Western Han Chinese. Lin Y, Shi J, Shi B, Jia Z. | 11/14/2023 |
M1 macrophage-derived exosomes containing miR-150 inhibit glioma progression by targeting MMP16. | M1 macrophage-derived exosomes containing miR-150 inhibit glioma progression by targeting MMP16. Yan P, Wang J, Liu H, Liu X, Fu R, Feng J. | 06/14/2023 |
LncRNA NEAT1 regulates MMP-16 by targeting miR-200a/b to aggravate inflammation in asthma. | LncRNA NEAT1 regulates MMP-16 by targeting miR-200a/b to aggravate inflammation in asthma. Duan XJ, Zhang X, Ding N, Zhang JY, Chen YP. | 04/2/2022 |
Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC). | Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC). Pietrzak J, Szmajda-Krygier D, Wosiak A, Świechowski R, Michalska K, Mirowski M, Żebrowska-Nawrocka M, Łochowski M, Balcerczak E. | 03/19/2022 |
Circular RNA hsa_circ_0002360 promotes non-small cell lung cancer progression through upregulating matrix metalloproteinase 16 and sponging multiple micorRNAs. | Circular RNA hsa_circ_0002360 promotes non-small cell lung cancer progression through upregulating matrix metalloproteinase 16 and sponging multiple micorRNAs. Zhang Y, Zeng S, Wang T., Free PMC Article | 02/19/2022 |
microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16. | microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16. Li W, Song Z, Jia N, Zhang C, Gao W, Wang L. | 01/29/2022 |
A protective polymorphism in MMP16, improved blood gas levels, and chronic obstructive pulmonary diseases: Family and two population-based studies. | A protective polymorphism in MMP16, improved blood gas levels, and chronic obstructive pulmonary diseases: Family and two population-based studies. Zhang Z, Wang J, Zheng Z, Chen X, Xu G, Chen S, Liu F, Chen L, Ding M, Yuan L, Li Y, Qian J, Xie X, Deng B, Lu W. | 11/6/2021 |
Association between MMP16 rs60298754 and clinical phenotypes of Parkinson's disease in southern Chinese. | Association between MMP16 rs60298754 and clinical phenotypes of Parkinson's disease in southern Chinese. Chen K, Guo MR, Zhang Y, Li G, Liu Y, Zhang B. | 09/18/2021 |
LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis. | LINC01121 induced intervertebral disc degeneration via modulating miR-150-5p/MMP16 axis. Chen X, Li Z, Xu D, Li S. | 08/21/2021 |
Role of lncRNA NEAT1 mediated by YY1 in the development of diabetic cataract via targeting the microRNA-205-3p/MMP16 axis. | Role of lncRNA NEAT1 mediated by YY1 in the development of diabetic cataract via targeting the microRNA-205-3p/MMP16 axis. Li Y, Jiang SH, Liu S, Wang Q. | 04/24/2021 |
Knockdown of MMP16 inhibits cell proliferation and invasion in chordoma in vitro. | Knockdown of MMP16 inhibits cell proliferation and invasion in chordoma in vitro. Xu DM, Han PH, Chen L, Li TT, Yang XH, Guo R. | 01/23/2021 |
HOXA11-AS could promote renal cancer cells growth and invasion by modulating miR-146b-5p-MMP16 axis. | HOXA11-AS promotes the growth and invasion of renal cancer by sponging miR-146b-5p to upregulate MMP16 expression. Yang FQ, Zhang JQ, Jin JJ, Yang CY, Zhang WJ, Zhang HM, Zheng JH, Weng ZM. | 10/5/2019 |
Overexpression of MMP2 and MMP16 in endometrial cancerous tissues corresponded to down-regulation of miR-377, miR-382 and miR-410, while decreased expression of TIMP2 was associated with miR-200b up-regulation. | Post-transcriptional Regulation of MMP16 and TIMP2 Expression via miR-382, miR-410 and miR-200b in Endometrial Cancer. Rak B, Mehlich D, Garbicz F, Domosud Z, Paskal W, Marczewska JM, Włodarski PK., Free PMC Article | 05/12/2018 |
MMP16 was highly expressed and correlated with poor prognosis in gastric cancer patients by promoting proliferation and invasion of gastric cancer cells | MMP16 is a marker of poor prognosis in gastric cancer promoting proliferation and invasion. Cao L, Chen C, Zhu H, Gu X, Deng D, Tian X, Liu J, Xiao Q., Free PMC Article | 01/13/2018 |
Findings suggest that these MMP16 rs10090371, ADAMTS3 rs788935, TLL2 rs10882807 and MMP9 rs3918251 may be promising prognostic biomarkers for cutaneous melanoma specific survival (CMSS). | Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. Xu Y, Wang Y, Liu H, Shi Q, Zhu D, Amos CI, Fang S, Lee JE, Hyslop T, Li X, Han J, Wei Q., Free PMC Article | 12/23/2017 |
the present findings indicate that MT3-MMP is down-regulated in ESCC, which correlates to lymph node metastasis and poor survival of patients with this disease. | MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma. Xue Z, Wu X, Chen X, Luo Q., Free PMC Article | 11/18/2017 |
more severe intervertebral disc degeneration is correlated with higher matrix metallopeptidase 16 | Role of miR-155 in the regulation of MMP-16 expression in intervertebral disc degeneration. Zhang WL, Chen YF, Meng HZ, Du JJ, Luan GN, Wang HQ, Yang MW, Luo ZJ., Free PMC Article | 10/7/2017 |
results suggest that miR-145 functions as a tumor metastasis suppressor gene by down-regulating MMP16 and may be a potential target in osteosarcoma treatment | MicroRNA-145 Suppresses Osteosarcoma Metastasis via Targeting MMP16. Chen B, Huang Z, Zhang Y, Chen Y, Li Z. | 10/22/2016 |
the results support a role for MMP16 in promoting invasive properties of the meningioma tumours | A role for matrix remodelling proteins in invasive and malignant meningiomas. Jalali S, Singh S, Agnihotri S, Wataya T, Salehi F, Alkins R, Burrell K, Navab R, Croul S, Aldape K, Zadeh G. | 01/2/2016 |
These results demonstrate that the MT3-MMP promoter is frequently hypermethylated in colorectal cancer and that downregulation of MT3-MMP may be important for cell migration in colorectal cancer. | Promoter hypermethylation of membrane type 3 matrix metalloproteinase is associated with cell migration in colorectal adenocarcinoma. Moon JW, Choi JH, Lee SK, Lee YW, Lee JO, Kim N, Lee HJ, Seo JS, Kim J, Kim HS, Kim GJ, Park SH. | 08/29/2015 |
MMP16 is a putative indicator of adverse melanoma prognosis. | MMP16 Mediates a Proteolytic Switch to Promote Cell-Cell Adhesion, Collagen Alignment, and Lymphatic Invasion in Melanoma. Tatti O, Gucciardo E, Pekkonen P, Holopainen T, Louhimo R, Repo P, Maliniemi P, Lohi J, Rantanen V, Hautaniemi S, Alitalo K, Ranki A, Ojala PM, Keski-Oja J, Lehti K. | 08/1/2015 |
Expression of MMP-16 in HTB9 and T24 cells increases following transforming growth factorbeta1 treatment. | Transforming growth factor‑β1 induces epithelial‑mesenchymal transition and increased expression of matrix metalloproteinase‑16 via miR‑200b downregulation in bladder cancer cells. Chen MF, Zeng F, Qi L, Zu XB, Wang J, Liu LF, Li Y. | 05/16/2015 |
E2F1 acts as a transcriptional activator for MMPs and directly enhances MMP transcription by binding to E2F1 binding sequences in the promoter, or indirectly activates MMPs (MMP-9 and MMP-16)through enhanced Sp1 and NF-kappa B | Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype. Li Z, Guo Y, Jiang H, Zhang T, Jin C, Young CY, Yuan H., Free PMC Article | 12/20/2014 |
Matrix metalloproteinase 16 (MMP16) was a downstream target of miR-146b-5p. | Inhibitory effects of miR-146b-5p on cell migration and invasion of pancreatic cancer by targeting MMP16. Lin F, Wang X, Jie Z, Hong X, Li X, Wang M, Yu Y. | 09/13/2014 |
The overexpression of miR-146b-5p in glioblastoma cell lines led to MMP16 mRNA silencing, MMP2 inactivation, and the inhibition of tumour cell migration and invasion. | miR-146b-5p inhibits glioma migration and invasion by targeting MMP16. Li Y, Wang Y, Yu L, Sun C, Cheng D, Yu S, Wang Q, Yan Y, Kang C, Jin S, An T, Shi C, Xu J, Wei C, Liu J, Sun J, Wen Y, Zhao S, Kong Y. | 11/16/2013 |