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    MNDA myeloid cell nuclear differentiation antigen [ Homo sapiens (human) ]

    Gene ID: 4332, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.

    MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.
    Bottardi S, Layne T, Ramòn AC, Quansah N, Wurtele H, Affar EB, Milot E., Free PMC Article

    06/24/2024
    MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells.

    MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells.
    Bottardi S, Guieze R, Bourgoin V, Fotouhi-Ardakani N, Dougé A, Darracq A, Lakehal YA, Berger MG, Mollica L, Bay JO, Omichinski JG, Milot E.

    12/12/2020
    IRTA1 and MNDA are useful markers in the differential diagnosis of marginal zone lymphomas (MZLs).

    IRTA1 and MNDA Expression in Marginal Zone Lymphoma: Utility in Differential Diagnosis and Implications for Classification.
    Wang Z, Cook JR.

    01/4/2020
    MFC adds significant information on dyspoiesis in the diagnostic work up for MDS and provides prognostic information. MNDA expression can be assessed by MFC and may facilitate evaluation of dyspoiesis when added to MDS MFC panels.

    Flow cytometry in the diagnosis of myelodysplastic syndromes and the value of myeloid nuclear differentiation antigen.
    Bellos F, Kern W.

    02/24/2018
    MNDA expression is an independent marker for the evaluation of dyspoiesis and may be added to the standard panel for quantitative assessment by FCM.

    Value of Quantitative assessment of Myeloid Nuclear Differentiation Antigen expression and other flow cytometric parameters in the diagnosis of Myelodysplastic syndrome.
    Somasundaram V, Soni S, Chopra A, Rai S, Mahapatra M, Kumar R, Pati H.

    12/17/2016
    Studied the HIN domain of recombinant myeloid nuclear differentiation antigen (MNDA).

    Purification, characterization and docking studies of the HIN domain of human myeloid nuclear differentiation antigen (MNDA).
    Li H, Wang ZX, Wu JW.

    12/6/2014
    these data support the inclusion of MNDA in the diagnostic evaluation of extramedullary B-cell lymphomas, particularly those in which the differential diagnosis is between low-grade follicular lymphoma and marginal zone lymphoma.

    Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma.
    Metcalf RA, Monabati A, Vyas M, Roncador G, Gualco G, Bacchi CE, Younes SF, Natkunam Y, Freud AG.

    09/27/2014
    Myeloid antigen expression is a predictor of a poor response to chemotherapy, and an adverse prognostic factor in adult T-lymphoblastic lymphoma, but not in children with T-LBL.

    Significance of myeloid antigen expression in precursor T lymphoblastic lymphoma.
    Cai Y, Sun XF, Yan SL, Zhen ZJ, Xia Y, Ling JY.

    02/11/2012
    Observational study of gene-disease association. (HuGE Navigator)

    Association of IFI200 gene polymorphisms with susceptibility to systemic lupus erythematosus.
    Kimkong I, Avihingsanon Y, Hirankarn N.

    09/15/2010
    MNDA expression is a useful tool for the recognition of nodal marginal zone lymphoma

    Identification of MNDA as a new marker for nodal marginal zone lymphoma.
    Kanellis G, Roncador G, Arribas A, Mollejo M, Montes-Moreno S, Maestre L, Campos-Martin Y, Ríos Gonzalez JL, Martinez-Torrecuadrada JL, Sanchez-Verde L, Pajares R, Cigudosa JC, Martin MC, Piris MA.

    01/21/2010
    MNDA has a role regulating programmed cell death in myeloid progenitor cells, and that its down-regulation in myelodysplastic syndromes is related to granulocyte-macrophage progenitor cell sensitivity to TRAIL-induced programmed cell death.

    Dysregulated human myeloid nuclear differentiation antigen expression in myelodysplastic syndromes: evidence for a role in apoptosis.
    Briggs RC, Shults KE, Flye LA, McClintock-Treep SA, Jagasia MH, Goodman SA, Boulos FI, Jacobberger JW, Stelzer GT, Head DR.

    01/21/2010
    variation in MNDA expression appeared to change with phenotypic specialization of monocytes in atherosclerosis consistent with its association with inflammation and suspected roles in regulating gene expression or in mediating cell death

    Variable expression of human myeloid specific nuclear antigen MNDA in monocyte lineage cells in atherosclerosis.
    Briggs RC, Atkinson JB, Miranda RN.

    01/21/2010
    Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression

    Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression.
    Doggett KL, Briggs JA, Linton MF, Fazio S, Head DR, Xie J, Hashimoto Y, Laborda J, Briggs RC.

    01/21/2010
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