| CCND1-associated ceRNA network reveal the critical pathway of TPRG1-AS1-hsa-miR-363-3p-MYO1B as a prognostic marker for head and neck squamous cell carcinoma. | CCND1-associated ceRNA network reveal the critical pathway of TPRG1-AS1-hsa-miR-363-3p-MYO1B as a prognostic marker for head and neck squamous cell carcinoma.
Li Z, Qiu X, He Q, Fu X, Ji F, Tian X., Free PMC Article | 07/27/2023 |
| MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma. | MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma.
Sun Z, Guo X, Chen H, Ling J, Zhao H, Chang A, Zhuo X. | 06/15/2023 |
| Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging. | Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.
Yu Y, Ren Y, Li Z, Li Y, Li Y, Zhang Y, Gui R, Cui Y, Qian L, Xiong Y., Free PMC Article | 01/28/2023 |
| Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1alpha in colorectal cancer. | Myo1b promotes tumor progression and angiogenesis by inhibiting autophagic degradation of HIF-1α in colorectal cancer.
Chen YH, Xu NZ, Hong C, Li WQ, Zhang YQ, Yu XY, Huang YL, Zhou JY., Free PMC Article | 11/19/2022 |
| Targeting MYO1B impairs tumorigenesis via inhibiting the SNAI2/cyclin D1 signaling in esophageal squamous cell carcinoma. | Targeting MYO1B impairs tumorigenesis via inhibiting the SNAI2/cyclin D1 signaling in esophageal squamous cell carcinoma.
Li SH, Qian L, Chen YH, Lu HI, Tsai HT, Lyu H, Yang R, Chen CH. | 10/15/2022 |
| F-actin depolymerizes when sliding on immobilized Myo1b. | Myosin 1b is an actin depolymerase.
Pernier J, Kusters R, Bousquet H, Lagny T, Morchain A, Joanny JF, Bassereau P, Coudrier E., Free PMC Article | 03/14/2020 |
| identify SRSF1 as an important oncodriver that integrates AS control of MYO1B into promotion of gliomagenesis and represents a potential prognostic biomarker and target for glioma therapy. | Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B.
Zhou X, Wang R, Li X, Yu L, Hua D, Sun C, Shi C, Luo W, Rao C, Jiang Z, Feng Y, Wang Q, Yu S., Free PMC Article | 12/21/2019 |
| The authors report here the identification of a novel Toxoplasma effector protein that is exported from the parasitophorous vacuole in a MYR1-dependent manner and localizes to the host's nucleus. Parasites lacking this inducer of host cyclin E (HCE1) are unable to modulate E2F transcription factor target genes, including cyclin E, and exhibit a substantial growth defect. | Toxoplasma Controls Host Cyclin E Expression through the Use of a Novel MYR1-Dependent Effector Protein, HCE1.
Panas MW, Naor A, Cygan AM, Boothroyd JC., Free PMC Article | 06/29/2019 |
| Data suggested a potential role of Myo1b in cervical carcinogenesis and tumor progression and provided novel insights into the mechanism of how this factor promotes cell proliferation, migration, and invasion in CC cells. | Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Zhang HR, Lai SY, Huang LJ, Zhang ZF, Liu J, Zheng SR, Ding K, Bai X, Zhou JY. | 07/14/2018 |
| Data demonstrated that the passenger strand of miR145 acted as an antitumor miRNA through targeting MYO1B in HNSCC cells. The involvement of dual strands of premiR145 (miR1455p and miR1453p) in the regulation of HNSCC pathogenesis is a novel concept in present RNA research. | Passenger strand of miR-145-3p acts as a tumor-suppressor by targeting MYO1B in head and neck squamous cell carcinoma.
Yamada Y, Koshizuka K, Hanazawa T, Kikkawa N, Okato A, Idichi T, Arai T, Sugawara S, Katada K, Okamoto Y, Seki N., Free PMC Article | 06/9/2018 |
| Identify MTO1b as a novel pericyte marker. | Phenotypic characterization of perivascular myoid cell neoplasms, using myosin 1B, a newly identified human pericyte marker.
Meguro S, Akamatsu T, Matsushima S, Kosugi I, Kawasaki H, Arai Y, Baba S, Tsuchida T, Shido Y, Suda T, Iwashita T. | 04/29/2017 |
| the overexpression of miR-363 reduces cellular migration in head and neck cancer and reveal the biological relationship between miR-363, myosin 1b, and HPV-positive SCCHN. | MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer.
Chapman BV, Wald AI, Akhtar P, Munko AC, Xu J, Gibson SP, Grandis JR, Ferris RL, Khan SA., Free PMC Article | 07/16/2016 |
| Myosin 1 functions as an effector of EphB2/ephrinB signaling, controls cell morphology, and thereby cell repulsion. | Myosin 1b functions as an effector of EphB signaling to control cell repulsion.
Prospéri MT, Lépine P, Dingli F, Paul-Gilloteaux P, Martin R, Loew D, Knölker HJ, Coudrier E., Free PMC Article | 04/30/2016 |
| Results showed that aberrant overexpression of Myo1b in human head and neck squamous cell carcinoma increased cancer cell motility via enhanced large protrusion formation of cell membrane and promotes lymph node metastasis. | Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC.
Ohmura G, Tsujikawa T, Yaguchi T, Kawamura N, Mikami S, Sugiyama J, Nakamura K, Kobayashi A, Iwata T, Nakano H, Shimada T, Hisa Y, Kawakami Y. | 02/6/2016 |
| Myosin 1b catch-bond properties facilitate tube extraction under conditions of increasing membrane tension by reducing the density of myo1b required to pull tubes. | Catch-bond behaviour facilitates membrane tubulation by non-processive myosin 1b.
Yamada A, Mamane A, Lee-Tin-Wah J, Di Cicco A, Prévost C, Lévy D, Joanny JF, Coudrier E, Bassereau P. | 10/3/2015 |
| Actin and myosin 1 regulate organelle shape and uncover an important function for myosin 1b in the initiation of post-Golgi carrier formation by regulating actin assembly and remodelling trans-Golgi network membranes. | Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network.
Almeida CG, Yamada A, Tenza D, Louvard D, Raposo G, Coudrier E. | 09/10/2011 |
| Sensing molecular tension is crucial for a wide array of cellular processes. Myosin I dramatically alters its motile properties in response to tension. | Myosin I can act as a molecular force sensor.
Laakso JM, Lewis JH, Shuman H, Ostap EM., Free PMC Article | 10/9/2008 |
| At apical surfaces of supporting cells that surround hair cells in auditory epithelia of postnatal rats. In vestibular epithelia, present in ring within apical pole of hair cell. Expression was prominent only immediately after birth. | Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia.
Dumont RA, Zhao YD, Holt JR, Bähler M, Gillespie PG., Free PMC Article | 01/21/2010 |
| observations suggest that myosin 1b controls the traffic of protein cargo in multivesicular endosomes most probably through its ability to modulate with actin the morphology of these sorting endosomes | Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes.
Salas-Cortes L, Ye F, Tenza D, Wilhelm C, Theos A, Louvard D, Raposo G, Coudrier E. | 01/21/2010 |