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    MYBL2 MYB proto-oncogene like 2 [ Homo sapiens (human) ]

    Gene ID: 4605, updated on 1-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Single-cell RNA sequencing reveals that MYBL2 in malignant epithelial cells is involved in the development and progression of ovarian cancer.

    Single-cell RNA sequencing reveals that MYBL2 in malignant epithelial cells is involved in the development and progression of ovarian cancer.
    Shao W, Lin Z, Xiahou Z, Zhao F, Xu J, Liu X, Cai P., Free PMC Article

    09/25/2024
    Ectopic MYBL2-Mediated Regulation of Androglobin Gene Expression.

    Ectopic MYBL2-Mediated Regulation of Androglobin Gene Expression.
    Herwig A, Osterhof C, Keppner A, Maric D, Koay TW, Mbemba-Nsungi A, Hoogewijs D., Free PMC Article

    09/11/2024
    MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer.

    MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer.
    German B, Alaiwi SA, Ho KL, Nanda JS, Fonseca MA, Burkhart DL, Sheahan AV, Bergom HE, Morel KL, Beltran H, Hwang JH, Freedman ML, Lawrenson K, Ellis L., Free PMC Article

    09/9/2024
    CircMYBL2 facilitates hepatocellular carcinoma progression by regulating E2F1 expression.

    CircMYBL2 facilitates hepatocellular carcinoma progression by regulating E2F1 expression.
    Yi J, Li B, Yin X, Liu L, Song C, Zhao Y, Cai M, Tang H, Chen D, Lyu N., Free PMC Article

    08/29/2024
    B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2.

    B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2.
    Fan X, Wang Y, Jiang T, Liu T, Jin Y, Du K, Niu Y, Zhang C, Liu Z, Lei Y, Bu Y., Free PMC Article

    08/28/2024
    Up-regulation of RAN by MYBL2 maintains osteosarcoma cancer stem-like cells population during heterogeneous tumor generation.

    Up-regulation of RAN by MYBL2 maintains osteosarcoma cancer stem-like cells population during heterogeneous tumor generation.
    Gao W, Zhou J, Huang J, Zhang Z, Chen W, Zhang R, Kang T, Liao D, Zhong L.

    03/19/2024
    Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers.

    Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers.
    Jessen M, Gertzmann D, Liss F, Zenk F, Bähner L, Schöffler V, Schulte C, Maric HM, Ade CP, von Eyss B, Gaubatz S., Free PMC Article

    02/22/2024
    Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.

    Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.
    Hui YJ, Chen H, Peng XC, Li LG, Di MJ, Liu H, Hu XH, Yang Y, Zhao KL, Li TF, Yu TT, Wang WX.

    07/6/2023
    Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer.

    Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer.
    Brahim S, Negulescu AM, Geneste C, Schott T, Lin S, Morel LO, Rama N, Gadot N, Treilleux I, Mehlen P, Meurette O., Free PMC Article

    03/24/2023
    Transcription factor B-MYB activates lncRNA CCAT1 and upregulates SOCS3 to promote chemoresistance in colorectal cancer.

    Transcription factor B-MYB activates lncRNA CCAT1 and upregulates SOCS3 to promote chemoresistance in colorectal cancer.
    Liu F, Wang Y, Cao Y, Wu Z, Ma D, Cai J, Sha J, Chen Q.

    03/14/2023
    MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells.

    MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells.
    Zhao JZ, Wang W, Liu T, Zhang L, Lin DZ, Yao JY, Peng X, Jin G, Ma TT, Gao JB, Huang F, Nie J, Lv Q., Free PMC Article

    12/31/2022
    MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3.

    MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3.
    Liu W, Shen D, Ju L, Zhang R, Du W, Jin W, Xiong K, Wang G, Qian K, Zhang Y, Xiao Y, Wang X.

    10/15/2022
    [High expression of MYBL2 promotes progression and predicts a poor survival outcome of prostate cancer].

    [High expression of MYBL2 promotes progression and predicts a poor survival outcome of prostate cancer].
    Yang M, Zhu X, Shen Y, He Q, Qin Y, Shao Y, Yuan L, Ye H., Free PMC Article

    09/17/2022
    Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cells.

    Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cells.
    Li J, Chen H., Free PMC Article

    07/30/2022
    LncRNA-MALAT1 Regulates Cancer Glucose Metabolism in Prostate Cancer via MYBL2/mTOR Axis.

    LncRNA-MALAT1 Regulates Cancer Glucose Metabolism in Prostate Cancer via MYBL2/mTOR Axis.
    Mu X, Shen Z, Lin Y, Xiao J, Xia K, Xu C, Chen B, Shi R, Zhu A, Sun X, Tao T, Song X, Xuan Q., Free PMC Article

    05/21/2022
    MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.

    MYB proto-oncogene like 2 promotes hepatocellular carcinoma growth and glycolysis via binding to the Optic atrophy 3 promoter and activating its expression.
    Liu M, Du Q, Mao G, Dai N, Zhang F., Free PMC Article

    04/23/2022
    Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene.

    Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene.
    Chen X, Lu Y, Yu H, Du K, Zhang Y, Nan Y, Huang Q., Free PMC Article

    04/16/2022
    Elevated expression of the MYB proto-oncogene like 2 (MYBL2)-encoding gene as a prognostic and predictive biomarker in human cancers.

    Elevated expression of the MYB proto-oncogene like 2 (MYBL2)-encoding gene as a prognostic and predictive biomarker in human cancers.
    Xin Z, Li Y, Meng L, Dong L, Ren J, Men J.

    03/19/2022
    B-Myb participated in ionizing radiation-induced apoptosis and cell cycle arrest in human glioma cells.

    B-Myb participated in ionizing radiation-induced apoptosis and cell cycle arrest in human glioma cells.
    Shen X, Cao H, Zhu Y, Zhao Y, Liu Y, Zuo W, Lin F, Liang Z.

    11/22/2021
    MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.

    MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.
    Deng Q, Wu L, Li Y, Zou L.

    10/9/2021
    Overexpression of <em>MYBL2</em> predicts poor prognosis and promotes oncogenesis in endometrial carcinoma.

    Overexpression of <em>MYBL2</em> predicts poor prognosis and promotes oncogenesis in endometrial carcinoma.
    Le L, Luo J, Wu H, Chen L, Tang X, Fu F., Free PMC Article

    09/11/2021
    The role of MYB proto-oncogene like 2 in tamoxifen resistance in breast cancer.

    The role of MYB proto-oncogene like 2 in tamoxifen resistance in breast cancer.
    Li X, Zhang X, Wu CC, Li PP, Fu YM, Xie LH, Sun SS, Zhou YY, Zhu BL.

    08/14/2021
    MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer.

    MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer.
    Li Q, Wang M, Hu Y, Zhao E, Li J, Ren L, Wang M, Xu Y, Liang Q, Zhang D, Lai Y, Liu S, Peng X, Zhu C, Ye L., Free PMC Article

    07/31/2021
    Gene network analysis using SWIM reveals interplay between the transcription factor-encoding genes HMGA1, FOXM1, and MYBL2 in triple-negative breast cancer.

    Gene network analysis using SWIM reveals interplay between the transcription factor-encoding genes HMGA1, FOXM1, and MYBL2 in triple-negative breast cancer.
    Fiscon G, Pegoraro S, Conte F, Manfioletti G, Paci P.

    07/31/2021
    circRNA circ-MYBL2 is a novel tumor suppressor and potential biomarker in multiple myeloma.

    circRNA circ-MYBL2 is a novel tumor suppressor and potential biomarker in multiple myeloma.
    Yu S, Ai L, Wei W, Pan J.

    07/3/2021
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