| MYH1 is a candidate gene for recurrent rhabdomyolysis in humans. | MYH1 is a candidate gene for recurrent rhabdomyolysis in humans.
Alsaif HS, Alshehri A, Sulaiman RA, Al-Hindi H, Guzmán-Vega FJ, Arold ST, Alkuraya FS. | 01/1/2022 |
| Transcriptional levels of MHC-I, MHC-IIa, and MHC-IIb in denervation groups were significantly down-regulated compared with controls | Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.
Qiu X, Chen D, Li M, Gao Y, Liu F, Zheng H, Chen S. | 04/2/2016 |
| Myosin isoforms impact single-fiber force generation and may lead to alterations in whole skeletal muscle performance. | Molecular determinants of force production in human skeletal muscle fibers: effects of myosin isoform expression and cross-sectional area.
Miller MS, Bedrin NG, Ades PA, Palmer BM, Toth MJ., Free PMC Article | 09/26/2015 |
| adaptive response to reduced masticatory load was lower numerical and area proportion of MyHC-1 expressing fibres and higher numerical proportion of hybrid fibres in edentulous compared with dentate subjects | Wearing of complete dentures reduces slow fibre and enhances hybrid fibre fraction in masseter muscle.
Cvetko E, Karen P, Eržen I. | 09/29/2012 |
| The human genioglossus muscle is composed of conventional myosin heavy chain isoforms and 3 primary myosin heavy chain phenotypes. | Myosin heavy chain composition of the human genioglossus muscle.
Daugherty M, Luo Q, Sokoloff AJ., Free PMC Article | 08/11/2012 |
| the expression levels of the MHC genes are associated with age and both PGC-1alpha and PGC-1beta and indicate that the MHC genes may to some extent be used to determine fibre-type composition in human skeletal muscle. | The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.
Olsson AH, Rönn T, Elgzyri T, Hansson O, Eriksson KF, Groop L, Vaag A, Poulsen P, Ling C. | 10/15/2011 |
| we found a higher percentage of fibers expressing fast MyHC IIx in tetraplegic cerebral palsy | Higher amount of MyHC IIX in a wrist flexor in tetraplegic compared to hemiplegic cerebral palsy.
Pontén E, Lindström M, Kadi F. | 10/21/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Analysis of candidate genes in occurrence and growth of colorectal adenomas.
Olschwang S, Vernerey D, Cottet V, Pariente A, Nalet B, Lafon J, Faivre J, Laurent-Puig P, Bonithon-Kopp C, Bonaiti-Pellié C., Free PMC Article | 12/2/2009 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | See all PubMed (2) articlesVariation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators. Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.
Kweekel DM, Antonini NF, Nortier JW, Punt CJ, Gelderblom H, Guchelaar HJ. | 08/12/2009 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Genetic polymorphisms in hMTH1, hOGG1 and hMYH and risk of chronic benzene poisoning in a Chinese occupational population.
Wu F, Zhang Z, Wan J, Gu S, Liu W, Jin X, Xia Z. | 11/2/2008 |
| Patients on hemodialysis demonstrate relatively fewer type 1 and consequently more type 2x fibres, with a corresponding change in MHC isoforms (MHC I and MHC IIX) in the skeletal muscle. | Myosin heavy-chain isoform distribution, fibre-type composition and fibre size in skeletal muscle of patients on haemodialysis.
Molsted S, Eidemak I, Sorensen HT, Kristensen JH, Harrison A, Andersen JL. | 01/21/2010 |
| Observational study of genotype prevalence. (HuGE Navigator) | See all PubMed (3) articlesColorectal adenomatous polyposis Associated with MYH mutations: genotype and phenotype characteristics.
Bouguen G, Manfredi S, Blayau M, Dugast C, Buecher B, Bonneau D, Siproudhis L, David V, Bretagne JF. Mutation analysis of the MYH gene in unrelated Czech APC mutation-negative polyposis patients.
Sulová M, Zídková K, Kleibl Z, Stekrová J, Kebrdlová V, Bortlík M, Lukás M, Kohoutová M. Is prophylactic colectomy indicated in patients with MYH-associated polyposis?
Leite JS, Isidro G, Martins M, Regateiro F, Albuquerque O, Amaro P, Romãozinho JM, Boavida G, Castro-Sousa F. | 03/13/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (10) articlesEvaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.
Shyy W, Wang K, Sheffield VC, Morcuende JA. A common mutation of the MYH gene is associated with increased DNA oxidation and age-related diseases.
Sun C, Chen H, Guo W, Zhang K, Qi Q, Gu X, Zhu D, Wang Y. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. APC, MYH, and the correlation genotype-phenotype in colorectal polyposis.
Lefevre JH, Parc Y, Svrcek M, Kernéis S, Colas C, Shields C, Flejou JF, Parc R, Tiret E. Similar colorectal cancer risk in patients with monoallelic and biallelic mutations in the MYH gene identified in a population with adenomatous polyposis.
Olschwang S, Blanché H, de Moncuit C, Thomas G. MYH, OGG1, MTH1, and APC alterations involved in the colorectal tumorigenesis of Korean patients with multiple adenomas.
Kim JC, Ka IH, Lee YM, Koo KH, Kim HC, Yu CS, Jang SJ, Kim YS, Lee HI, Lee KH. Germline mutations and polymorphic variants in MMR, E-cadherin and MYH genes associated with familial gastric cancer in Jiangsu of China.
Zhang Y, Liu X, Fan Y, Ding J, Xu A, Zhou X, Hu X, Zhu M, Zhang X, Li S, Wu J, Cao H, Li J, Wang Y. Risk of colorectal cancer in monoallelic and biallelic carriers of MYH mutations: a population-based case-family study.
Jenkins MA, Croitoru ME, Monga N, Cleary SP, Cotterchio M, Hopper JL, Gallinger S. MYH Y165C and G382D mutations in hepatocellular carcinoma and cholangiocarcinoma patients.
Baudhuin LM, Roberts LR, Enders FT, Swanson RL, Mettler TA, Aderca I, Stadheim LM, Highsmith WE. Role of inherited defects of MYH in the development of sporadic colorectal cancer.
Kambara T, Whitehall VL, Spring KJ, Barker MA, Arnold S, Wynter CV, Matsubara N, Tanaka N, Young JP, Leggett BA, Jass JR. | 03/13/2008 |
| Observational study and meta-analysis of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesThe role of MYH gene in genetic predisposition to colorectal cancer: another piece of the puzzle.
Avezzù A, Agostini M, Pucciarelli S, Lise M, Urso ED, Mammi I, Maretto I, Enzo MV, Pastrello C, Lise M, Nitti D, Viel A. Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study.
Balaguer F, Castellví-Bel S, Castells A, Andreu M, Muñoz J, Gisbert JP, Llor X, Jover R, de Cid R, Gonzalo V, Bessa X, Xicola RM, Pons E, Alenda C, Payá A, Piqué JM, Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. | 03/13/2008 |
| Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal gene family | Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal myosin heavy chain gene family.
Konig S, Burkman J, Fitzgerald J, Mitchell M, Su L, Stedman H. | 01/21/2010 |
| frequency of fibers expressing myosin heavy chain (MyHC) IIx increased in spastic paresis | Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis.
Pontén EM, Stål PS. | 01/21/2010 |