Myogenin suppresses apoptosis induced by angiotensin II in human induced pluripotent stem cell-derived cardiomyocytes. | Myogenin suppresses apoptosis induced by angiotensin II in human induced pluripotent stem cell-derived cardiomyocytes. Gao Q, Wang P, Qiu H, Qiu B, Yi W, Tu W, Lin B, Sun D, Zeng R, Huang M, Chen J, Cen J, Zhuang J. | 07/3/2021 |
The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network. | The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network. Codato R, Perichon M, Divol A, Fung E, Sotiropoulos A, Bigot A, Weitzman JB, Medjkane S., Free PMC Article | 11/21/2020 |
Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture. | Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture. Cooper LM, West RC, Hayes CS, Waddell DS. | 10/24/2020 |
CASZ1 plays a critical role in inducing skeletal myogenesis and co-operating to form a feed-forward loop with MYOD and MYOG that is critical for Embryonal rhabdomyosarcoma differentiation. | CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG. Liu Z, Zhang X, Lei H, Lam N, Carter S, Yockey O, Xu M, Mendoza A, Hernandez ER, Wei JS, Khan J, Yohe ME, Shern JF, Thiele CJ., Free PMC Article | 06/6/2020 |
PRMT1 promotes MyoD-mediated myogenin expression, for which the enzymatic activity of PRMT1 is needed. The arginine methylation of MyoD by PRMT1 enhances its DNA binding activity and transactivation. | PRMT1 activates myogenin transcription via MyoD arginine methylation at R121. Liu Q, Zhang XL, Cheng MB, Zhang Y. | 02/1/2020 |
Among these targets, dehydrogenase/reductase member 2 DHRS2 and MYO1B were directly regulated by miR1453p in esophageal squamous cell carcinoma (ESCC) cells by dual luciferase reporter assays. Aberrantly expressed DHRS2 and MYOIB were detected in ESCC clinical specimens, and their overexpression enhanced cancer cell aggressiveness. | Molecular pathogenesis of esophageal squamous cell carcinoma: Identification of the antitumor effects of miR‑145‑3p on gene regulation. Shimonosono M, Idichi T, Seki N, Yamada Y, Arai T, Arigami T, Sasaki K, Omoto I, Uchikado Y, Kita Y, Kurahara H, Maemura K, Natsugoe S. | 04/6/2019 |
Findings indicate a interplay between A-kinase anchoring protein 6 (AKAP6) and myogenin. | AKAP6 inhibition impairs myoblast differentiation and muscle regeneration: Positive loop between AKAP6 and myogenin. Lee SW, Won JY, Yang J, Lee J, Kim SY, Lee EJ, Kim HS., Free PMC Article | 10/22/2016 |
results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle | Myogenin is a positive regulator of MEGF10 expression in skeletal muscle. Park SY, Yun Y, Kim MJ, Kim IS. | 11/8/2014 |
Sustained GSK3beta activity represses a critical regulatory step in the myogenic cascade, contributing to the undifferentiated, proliferative phenotype in alveolar rhabdomyosarcoma. | Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma. Dionyssiou MG, Ehyai S, Avrutin E, Connor MK, McDermott JC., Free PMC Article | 10/25/2014 |
Our study illustrates that focal myogenin immunoreactivity occurs uncommonly in fibroepithelial polyps of the lower female genital tract. | Myogenin expression in vulvovaginal spindle cell lesions: analysis of a series of cases with an emphasis on diagnostic pitfalls. McCluggage WG, Longacre TA, Fisher C. | 09/27/2014 |
Data indicate that muscle MYOG mRNA expression doubled, whereas MSTN protein expression decreased following immobilization. | Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content. Snijders T, Wall BT, Dirks ML, Senden JM, Hartgens F, Dolmans J, Losen M, Verdijk LB, van Loon LJ. | 03/8/2014 |
SREBP-1 regulate muscle protein synthesis through the downregulation of the expression of MYOD1, MYOG and MEF2C factors. | SREBP-1 transcription factors regulate skeletal muscle cell size by controlling protein synthesis through myogenic regulatory factors. Dessalle K, Euthine V, Chanon S, Delarichaudy J, Fujii I, Rome S, Vidal H, Nemoz G, Simon C, Lefai E., Free PMC Article | 06/1/2013 |
the FACT complex promotes myogenin-dependent transcription | Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes. Lolis AA, Londhe P, Beggs BC, Byrum SD, Tackett AJ, Davie JK., Free PMC Article | 05/18/2013 |
Human muscle samples were analysed at different time-points post-denervation to evaluate changes in myogenin expression and their relationship with skeletal muscle atrophy. | The study of myogenin expression in denervated human skeletal muscles. Chen L, Huang HW, Gu SH, Xu L, Gu YD, Xu JG. | 10/15/2011 |
After 2 years of denervation, expression of myogenin protein in myonuclei was decreased, but after 3 years of denervation, no expression of myogenin protein in myonuclei was found in denervated posterior cricoarytenoid muscles. | [Correlation between myogenin and transforming growth factor-beta1 expression in long-term human denervated posterior cricoarytenoid muscles]. Zhang X, Zheng HL, Chen SC. | 05/21/2011 |
The physical interaction of CARM1 and PCAF is likely pivotal for the activation of PCAF in the downstream of CARM1 pathway for inducing myogenin under Tetradecanoylphorbol Acetate -induced differentiation. | CARM1 activates myogenin gene via PCAF in the early differentiation of TPA-induced rhabdomyosarcoma-derived cells. Gao X, Pan WS, Dai H, Zhang Y, Wu NH, Shen YF. | 07/26/2010 |
Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. | Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. Ramamoorthy S, Donohue M, Buck M., Free PMC Article | 01/21/2010 |
Observational study of gene-disease association. (HuGE Navigator) | High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, MrOS Research Group., Free PMC Article | 06/24/2009 |
Underexpression of myogenin is associated with liver metastases in rhabdomyosarcoma. | Opposing control of rhabdomyosarcoma growth and differentiation by myogenin and interleukin 4. Nanni P, Nicoletti G, Palladini A, Astolfi A, Rinella P, Croci S, Landuzzi L, Monduzzi G, Stivani V, Antognoli A, Murgo A, Ianzano M, De Giovanni C, Lollini PL. | 01/21/2010 |
PAX3 mRNA is an Staufen 1-mediated mRNA decay target whose decay promotes myogenesis whereas myogenin mRNA is a classical nonsense-mediated mRNA decay target encoding a protein required for myogenesis | SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Gong C, Kim YK, Woeller CF, Tang Y, Maquat LE., Free PMC Article | 01/21/2010 |
NFAT and MyoD cooperation regulates myogenin expression and myogenesis | Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. Armand AS, Bourajjaj M, Martínez-Martínez S, el Azzouzi H, da Costa Martins PA, Hatzis P, Seidler T, Redondo JM, De Windt LJ., Free PMC Article | 01/21/2010 |
Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma. | Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma: a tissue microarray study of 71 primary tumors including correlation with molecular phenotype. Heerema-McKenney A, Wijnaendts LC, Pulliam JF, Lopez-Terrada D, McKenney JK, Zhu S, Montgomery K, Mitchell J, Marinelli RJ, Hart AA, van de Rijn M, Linn SC. | 01/21/2010 |
Both PCAF and BRG1 are also involved in the activation of the myogenin gene in rhabdomyosarcoma | Sequential recruitment of PCAF and BRG1 contributes to myogenin activation in 12-O-tetradecanoylphorbol-13-acetate-induced early differentiation of rhabdomyosarcoma-derived cells. Li ZY, Yang J, Gao X, Lu JY, Zhang Y, Wang K, Cheng MB, Wu NH, Zhang Y, Wu Z, Shen YF. | 01/21/2010 |
transcription of Cugbp1 gene in muscle is regulated by myogenin and E proteins | Regulation of the promoter of CUG triplet repeat binding protein, Cugbp1, during myogenesis. Huichalaf CH, Sakai K, Wang GL, Timchenko NA, Timchenko L. | 01/21/2010 |
myogenin and myocyte enhancer factor-2 expression are triggered by membrane hyperpolarization during human myoblast differentiation | Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation. Konig S, Hinard V, Arnaudeau S, Holzer N, Potter G, Bader CR, Bernheim L. | 01/21/2010 |