| NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3. | NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3.
Parcerisas A, Pujadas L, Ortega-Gascó A, Perelló-Amorós B, Viais R, Hino K, Figueiro-Silva J, La Torre A, Trullás R, Simó S, Lüders J, Soriano E., Free PMC Article | 12/25/2021 |
| Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. | Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.
Kim W, Watanabe H, Lomoio S, Tesco G., Free PMC Article | 08/28/2021 |
| These results reveal that the NCAM2 FnIII domains form a rigid structure that binds and activates FGFR in a manner related to, but different from NCAM1. | NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.
Rasmussen KK, Falkesgaard MH, Winther M, Roed NK, Quistgaard CL, Teisen MN, Edslev SM, Petersen DL, Aljubouri A, Christensen C, Thulstrup PW, Lo Leggio L, Teilum K, Walmod PS., Free PMC Article | 10/12/2019 |
| Our reported case raises the questions whether the NCAM2-deletion is the true cause of the autism spectrum disorder or only a risk factor and whether there might be any connection in NCAM2 with skull-size | NCAM2 deletion in a boy with macrocephaly and autism: Cause, association or predisposition?
Scholz C, Steinemann D, Mälzer M, Roy M, Arslan-Kirchner M, Illig T, Schmidtke J, Stuhrmann M. | 02/18/2017 |
| Abeta-dependent disruption of NCAM2 functions in Alzheimer's disease hippocampus contributes to synapse loss. | Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.
Leshchyns'ka I, Liew HT, Shepherd C, Halliday GM, Stevens CH, Ke YD, Ittner LM, Sytnyk V., Free PMC Article | 05/28/2016 |
| A complete structural model of the entire ectodomain of human NCAM2 has been assembled from crystal structures of six recombinant proteins corresponding to different regions of the ectodomain. | Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule.
Kulahin N, Kristensen O, Rasmussen KK, Olsen L, Rydberg P, Vestergaard B, Kastrup JS, Berezin V, Bock E, Walmod PS, Gajhede M. | 07/2/2011 |
| High NCAM2 is associated with increased 5-Fluorouracil sensitivity in prostate and breast cancer. | Neural cell adhesion molecule 2 as a target molecule for prostate and breast cancer gene therapy.
Takahashi S, Kato K, Nakamura K, Nakano R, Kubota K, Hamada H. | 06/18/2011 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.
Han MR, Schellenberg GD, Wang LS, Alzheimer's Disease Neuroimaging Initiative., Free PMC Article | 12/5/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesAssociation of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.
Sokolowski M, Wasserman J, Wasserman D. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. | 01/11/2009 |
| In the crystal structure, two Ig domains interact by domain swapping, as the two N-terminal beta-strands are interchanged. | Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping.
Rasmussen KK, Kulahin N, Kristensen O, Poulsen JC, Sigurskjold BW, Kastrup JS, Berezin V, Bock E, Walmod PS, Gajhede M. | 01/21/2010 |