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    NEFL neurofilament light chain [ Homo sapiens (human) ]

    Gene ID: 4747, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Long COVID: plasma levels of neurofilament light chain in mild COVID-19 patients with neurocognitive symptoms.

    Long COVID: plasma levels of neurofilament light chain in mild COVID-19 patients with neurocognitive symptoms.
    Gutman EG, Salvio AL, Fernandes RA, Duarte LA, Raposo-Vedovi JV, Alcaraz HF, Teixeira MA, Passos GF, de Medeiros KQM, Hammerle MB, Pires KL, Vasconcelos CCF, Leon LAA, Figueiredo CP, Alves-Leon SV., Free PMC Article

    10/10/2024
    Investigation of serum neurofilament light chain as a biomarker in Fabry disease.

    Investigation of serum neurofilament light chain as a biomarker in Fabry disease.
    Ponleitner M, Gatterer C, Bsteh G, Rath J, Altmann P, Berger T, Graf S, Sunder-Plassmann G, Rommer PS., Free PMC Article

    10/10/2024
    Association between serum neurofilament light chains (sNfL) and neurologic disorders in a representative sample of US adults: a cross-sectional study.

    Association between serum neurofilament light chains (sNfL) and neurologic disorders in a representative sample of US adults: a cross-sectional study.
    Xu Q, Wang J, Li H, Gao Y.

    10/9/2024
    Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls.

    Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls.
    Bavato F, Barro C, Schnider LK, Simrén J, Zetterberg H, Seifritz E, Quednow BB., Free PMC Article

    09/25/2024
    Relationship between serum neurofilament light chain protein and depression: A nationwide survey and Mendelian randomization study.

    Relationship between serum neurofilament light chain protein and depression: A nationwide survey and Mendelian randomization study.
    Liu X, Chen X, Chen J.

    09/23/2024
    Dietary creatine is associated with lower serum neurofilament light chain levels.

    Dietary creatine is associated with lower serum neurofilament light chain levels.
    Ostojic SM, Grasaas E, Baltic S, Cvejic J.

    08/4/2024
    Cluster analysis dissecting cognitive deficits in older adults with major depressive disorder and the association with neurofilament light chain.

    Cluster analysis dissecting cognitive deficits in older adults with major depressive disorder and the association with neurofilament light chain.
    Chen CY, Chiu CC, Huang CY, Cheng YC, Huang MC, Kuo PH, Chen WY., Free PMC Article

    04/22/2024
    Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism.

    Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism.
    Huang MC, Tu HY, Chung RH, Kuo HW, Liu TH, Chen CH, Mochly-Rosen D, Liu YL., Free PMC Article

    03/12/2024
    Relationship between increased serum neurofilament light chain and glial fibrillary acidic protein levels with non-motor symptoms in patients with Parkinson's disease.

    Relationship between increased serum neurofilament light chain and glial fibrillary acidic protein levels with non-motor symptoms in patients with Parkinson's disease.
    Yin P, Niu X, Guan C, Zhang Z, Liu Y, Li J, Cui G, Zan K, Xu C.

    03/6/2024
    Inflammation affects dynamic functional network connectivity pattern changes via plasma NFL in cognitive impairment patients.

    Inflammation affects dynamic functional network connectivity pattern changes via plasma NFL in cognitive impairment patients.
    Yao W, Zhou H, Zhang X, Chen H, Bai F, Alzheimer's Disease Neuroimaging Initiative., Free PMC Article

    03/4/2024
    The impact of kidney function on plasma neurofilament light and phospho-tau 181 in a community-based cohort: the Shanghai Aging Study.

    The impact of kidney function on plasma neurofilament light and phospho-tau 181 in a community-based cohort: the Shanghai Aging Study.
    Wu J, Xiao Z, Wang M, Wu W, Ma X, Liang X, Zheng L, Ding S, Luo J, Cao Y, Hong Z, Chen J, Zhao Q, Ding D., Free PMC Article

    02/20/2024
    Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia: longitudinal data of the AGES-Reykjavik Study.

    Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia: longitudinal data of the AGES-Reykjavik Study.
    van Gennip ACE, Satizabal CL, Tracy RP, Sigurdsson S, Gudnason V, Launer LJ, van Sloten TT., Free PMC Article

    02/7/2024
    Plasma neurofilament light chain in association to late-life depression in the general population.

    Plasma neurofilament light chain in association to late-life depression in the general population.
    Schuurmans IK, Ghanbari M, Cecil CAM, Ikram MA, Luik AI.

    02/5/2024
    Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study.

    Serum NfL and GFAP are associated with incident dementia and dementia mortality in older adults: The cardiovascular health study.
    Cronjé HT, Liu X, Odden MC, Moseholm KF, Seshadri S, Satizabal CL, Lopez OL, Bis JC, Djoussé L, Fohner AE, Psaty BM, Tracy RP, Longstreth WT Jr, Jensen MK, Mukamal KJ.,

    01/4/2024
    Neurofilament Light Chain and Glial Fibrillary Acidic Protein as early prognostic biomarkers after out-of-hospital cardiac arrest.

    Neurofilament Light Chain and Glial Fibrillary Acidic Protein as early prognostic biomarkers after out-of-hospital cardiac arrest.
    Klitholm M, Jeppesen AN, Christensen S, Parkner T, Tybirk L, Kirkegaard H, Sandfeld-Paulsen B, Grejs AM.

    12/21/2023
    Clinical Evaluation of Cerebrospinal Fluid p217tau and Neurofilament Light Chain Levels in Patients with Alzheimer's Disease or Other Neurological Diseases.

    Clinical Evaluation of Cerebrospinal Fluid p217tau and Neurofilament Light Chain Levels in Patients with Alzheimer's Disease or Other Neurological Diseases.
    Kawarabayashi T, Nakamura T, Miyashita K, Segawa T, Fukamachi I, Sugawara T, Oka H, Ishizawa K, Amari M, Kasahara H, Makioka K, Ikeda Y, Takatama M, Shoji M., Free PMC Article

    12/21/2023
    Plasma neurofilament light chain predicts Alzheimer's disease in patients with subjective cognitive decline and mild cognitive impairment: A cross-sectional and longitudinal study.

    Plasma neurofilament light chain predicts Alzheimer's disease in patients with subjective cognitive decline and mild cognitive impairment: A cross-sectional and longitudinal study.
    Mazzeo S, Ingannato A, Giacomucci G, Manganelli A, Moschini V, Balestrini J, Cavaliere A, Morinelli C, Galdo G, Emiliani F, Piazzesi D, Crucitti C, Frigerio D, Polito C, Berti V, Bagnoli S, Padiglioni S, Sorbi S, Nacmias B, Bessi V., Free PMC Article

    12/20/2023
    LINC01579-204 involved in the development of Hirschsprung's disease maybe by regulating the expression of miR-203a-3p and NEFL.

    LINC01579-204 involved in the development of Hirschsprung's disease maybe by regulating the expression of miR-203a-3p and NEFL.
    Qin D, Yang W, Zhu X, Tang C, Yuan L, Xu L, Tian S, Huang R, Zhang D, Xiao S.

    12/6/2023
    Plasma biomarkers predict Alzheimer's disease before clinical onset in Chinese cohorts.

    Plasma biomarkers predict Alzheimer's disease before clinical onset in Chinese cohorts.
    Cai H, Pang Y, Fu X, Ren Z, Jia L., Free PMC Article

    12/3/2023
    Serum beta-synuclein, neurofilament light chain and glial fibrillary acidic protein as prognostic biomarkers in moderate-to-severe acute ischemic stroke.

    Serum β-synuclein, neurofilament light chain and glial fibrillary acidic protein as prognostic biomarkers in moderate-to-severe acute ischemic stroke.
    Barba L, Vollmuth C, Abu-Rumeileh S, Halbgebauer S, Oeckl P, Steinacker P, Kollikowski AM, Schultz C, Wolf J, Pham M, Schuhmann MK, Heuschmann PU, Haeusler KG, Stoll G, Neugebauer H, Otto M., Free PMC Article

    12/1/2023
    Neurofilament Light Chain as a Potential Biomarker in Plasma for Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and a Meta-Analysis.

    Neurofilament Light Chain as a Potential Biomarker in Plasma for Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and a Meta-Analysis.
    Fan Z, Liu X, Liu J, Chen C, Zhou M.

    11/16/2023
    Elevated plasma neurofilament light chain in immune-mediated neurological disorders (IMND) detected by immunomagnetic reduction (IMR).

    Elevated plasma neurofilament light chain in immune-mediated neurological disorders (IMND) detected by immunomagnetic reduction (IMR).
    Huang KY, Wu CL, Chang YS, Huang WY, Su FC, Lin SW, Chien YY, Weng WC, Wei YC.

    11/8/2023
    Clinically relevant increases in serum neurofilament light chain and glial fibrillary acidic protein in patients with Susac syndrome.

    Clinically relevant increases in serum neurofilament light chain and glial fibrillary acidic protein in patients with Susac syndrome.
    Plantone D, Sabatelli E, Locci S, Marrodan M, Laakso SM, Mateen FJ, Feresiadou A, Buelens T, Bianco A, Fiol MP, Correale J, Tienari P, Calabresi P, De Stefano N, Iorio R.

    09/12/2023
    Clinical Value of Longitudinal Serum Neurofilament Light Chain in Prodromal Genetic Frontotemporal Dementia.

    Clinical Value of Longitudinal Serum Neurofilament Light Chain in Prodromal Genetic Frontotemporal Dementia.
    Giannini LAA, Seelaar H, van der Ende EL, Poos JM, Jiskoot LC, Dopper EGP, Pijnenburg YAL, Willemse EAJ, Vermunt L, Teunissen CE, van Swieten JC, Meeter LH., Free PMC Article

    09/7/2023
    Association of serum neurofilament light with microglial activation in multiple sclerosis.

    Association of serum neurofilament light with microglial activation in multiple sclerosis.
    Saraste M, Matilainen M, Vuorimaa A, Laaksonen S, Sucksdorff M, Leppert D, Kuhle J, Airas L., Free PMC Article

    09/6/2023
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