Leishmania infantum exploits the anti-ferroptosis effects of Nrf2 to escape cell death in macrophages. | Leishmania infantum exploits the anti-ferroptosis effects of Nrf2 to escape cell death in macrophages. Blot C, Lavernhe M, Lugo-Villarino G, Coulson K, Salon M, Tertrais M, Planès R, Santoni K, Authier H, Jacquemin G, Rahabi M, Parny M, Letron IR, Meunier E, Lefèvre L, Coste A. | 10/2/2024 |
Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia. | Nrf2/ASPM axis regulated vasculogenic mimicry formation in hepatocellular carcinoma under hypoxia. Zhang Y, Che N, Wang S, Meng J, Zhao N, Han J, Dong X, Li Y, Mo J, Zhao X, Liu T. | 09/27/2024 |
GDF15 induces chemoresistance to oxaliplatin by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis in colorectal cancer. | GDF15 induces chemoresistance to oxaliplatin by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis in colorectal cancer. Lin H, Luo Y, Gong T, Fang H, Li H, Ye G, Zhang Y, Zhong M. | 09/25/2024 |
Modulation of osteoblastogenesis by NRF2: NRF2 activation suppresses osteogenic differentiation and enhances mineralization in human bone marrow-derived mesenchymal stromal cells. | Modulation of osteoblastogenesis by NRF2: NRF2 activation suppresses osteogenic differentiation and enhances mineralization in human bone marrow-derived mesenchymal stromal cells. Onoki T, Kanczler J, Rawlings A, Smith M, Kim YH, Hashimoto K, Aizawa T, Oreffo ROC. | 09/5/2024 |
A comparative analysis indicates SLC7A11 expression regulate the prognostic value of KEAP1-NFE2L2-CUL3 mutations in human uterine corpus endometrial carcinoma. | A comparative analysis indicates SLC7A11 expression regulate the prognostic value of KEAP1-NFE2L2-CUL3 mutations in human uterine corpus endometrial carcinoma. Namani A, Veeraiyan D, Patra T. | 08/29/2024 |
Knockdown of lncRNA NEAT1 suppresses streptococcus pneumoniae-induced ferroptosis in alveolar epithelial cells by regulating the Nrf2-GPX4 pathway. | Knockdown of lncRNA NEAT1 suppresses streptococcus pneumoniae-induced ferroptosis in alveolar epithelial cells by regulating the Nrf2-GPX4 pathway. Xu L, Zhang L, Xiang Y, Zhang X. | 08/21/2024 |
NRF2-HIF2alpha Signaling Attenuates Endothelial Cell Senescence and Maintains Intercellular Junctions in Diabetes. | NRF2-HIF2α Signaling Attenuates Endothelial Cell Senescence and Maintains Intercellular Junctions in Diabetes. Shen J, Lai Y, Lu Y, Liu Y, Zhang J, Wu Y, Pan Y, Chen H, Gao Q, Wei Q, Chen Y, Ye J, Lin Y, Liu B, Jiang J, Nan J., Free PMC Article | 08/9/2024 |
Correlation of PD-L1 expression with CD8+ T cells and oxidative stress-related molecules NRF2 and NQO1 in esophageal squamous cell carcinoma. | Correlation of PD-L1 expression with CD8+ T cells and oxidative stress-related molecules NRF2 and NQO1 in esophageal squamous cell carcinoma. Zhang X, Yang Y, Zhao H, Tian Z, Cao Q, Li Y, Gu Y, Song Q, Hu X, Jin M, Jiang X., Free PMC Article | 08/7/2024 |
NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells. | NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells. Choi G, Ju HY, Bok J, Choi J, Shin JW, Oh H, Jeon Y, Kim J, Kim D, Moon H, Lee JE, Keum YS, Kim YM, Kim HY, Park SH, Han MR, Chung Y., | 07/29/2024 |
Association Between Genes in the Nuclear Factor E2-Related Factor 2 Antioxidative Response Elements Pathway and Cancer-Related Fatigue in Women With Early-Stage Breast Cancer. | Association Between Genes in the Nuclear Factor E2-Related Factor 2 Antioxidative Response Elements Pathway and Cancer-Related Fatigue in Women With Early-Stage Breast Cancer. Davis TS, Koleck TA, Rosenzweig MQ, Miaskowski C, Erickson KI, Sereika SM, Bender CM, Conley YP. | 07/10/2024 |
Mitigation of ROS-triggered endoplasmic reticulum stress by upregulating Nrf2 retards diabetic nephropathy. | Mitigation of ROS-triggered endoplasmic reticulum stress by upregulating Nrf2 retards diabetic nephropathy. Zeng X, Zhang Y, Tian L, Zheng Y, Zhang J, Wu Z. | 06/14/2024 |
PPIA dictates NRF2 stability to promote lung cancer progression. | PPIA dictates NRF2 stability to promote lung cancer progression. Lu W, Cui J, Wang W, Hu Q, Xue Y, Liu X, Gong T, Lu Y, Ma H, Yang X, Feng B, Wang Q, Zhang N, Xu Y, Liu M, Nussinov R, Cheng F, Ji H, Huang J., Free PMC Article | 06/13/2024 |
Hyperactive behaviour of growth differentiation factor- 15 (GDF-15) in conjunction with iron trafficking transporters and suppression of Nrf-2 gene in diabetes and metabolic syndrome. | Hyperactive behaviour of growth differentiation factor- 15 (GDF-15) in conjunction with iron trafficking transporters and suppression of Nrf-2 gene in diabetes and metabolic syndrome. Saroj M, Prakash S, Vikram NK, Saraya A, Priyatma, Ganie MA, Arulselvi S, Pandey S. | 05/31/2024 |
MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes. | MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes. Franci L, Vallini G, Bertolino FM, Cicaloni V, Inzalaco G, Cicogni M, Tinti L, Calabrese L, Barone V, Salvini L, Rubegni P, Galvagni F, Chiariello M., Free PMC Article | 05/30/2024 |
Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern. | Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern. Xue Z, Nuerrula Y, Sitiwaerdi Y, Eli M., Free PMC Article | 05/30/2024 |
Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2. | Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2. Dong W, Li Q, Lu X, Lan J, Qiu Z, Wang X, Wang J, Zheng X, Chen S, Zhang C, Jin J., Free PMC Article | 05/1/2024 |
Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression. | Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression. Pan R, Wang R, Cheng F, Wang L, Cui Z, She J, Yang X., Free PMC Article | 04/29/2024 |
Potential Role of Nrf2, HER2, and ALDH in Cancer Stem Cells: A Narrative Review. | Potential Role of Nrf2, HER2, and ALDH in Cancer Stem Cells: A Narrative Review. Fakhrioliaei A, Tanhaei S, Pakmehr S, Noori Shakir M, Qasim MT, Hariri M, Nouhi Kararoudi A, Valilo M. | 04/17/2024 |
Role of kidney function on Nrf2 mRNA levels in type 2 diabetes. | Role of kidney function on Nrf2 mRNA levels in type 2 diabetes. Spoto B, Politi C, Postorino M, Parlongo RM, Testa A, Tripepi GL, Mallamaci F, Zoccali C., Free PMC Article | 04/12/2024 |
NRF2 regulates EGF stability through OTUD4 in lung adenocarcinoma. | NRF2 regulates EGF stability through OTUD4 in lung adenocarcinoma. Hu S, Yuan Y, Yan R, Xie H, Cai R, Xu J. | 04/12/2024 |
Combined genetic polymorphisms of the GSTT1 and NRF2 genes increase susceptibility to cisplatin-induced ototoxicity: A preliminary study. | Combined genetic polymorphisms of the GSTT1 and NRF2 genes increase susceptibility to cisplatin-induced ototoxicity: A preliminary study. Fujikawa T, Ito T, Okada R, Sawada M, Mohri K, Tateishi Y, Takahashi R, Asakage T, Tsutsumi T. | 04/12/2024 |
Hypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer. | Hypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer. Bae T, Hallis SP, Kwak MK., Free PMC Article | 04/5/2024 |
The crucial role of NRF2 in erythropoiesis and anemia: Mechanisms and therapeutic opportunities. | The crucial role of NRF2 in erythropoiesis and anemia: Mechanisms and therapeutic opportunities. Yang L, Chen Y, He S, Yu D. | 04/4/2024 |
Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury. | Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury. Tak J, Joo MS, Kim YS, Park HW, Lee CH, Park GC, Hwang S, Kim SG., Free PMC Article | 03/22/2024 |
Amino acid deprivation induces TXNIP expression by NRF2 downregulation. | Amino acid deprivation induces TXNIP expression by NRF2 downregulation. Ahn SH, Jang SK, Kim YJ, Kim G, Park KS, Park IC, Jin HO. | 03/20/2024 |