| The genes FABP7 and NFYC(-AS1) could play a role in airflow obstruction in never-smokers specifically. | Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population.
van der Plaat DA, Vonk JM, Lahousse L, de Jong K, Faiz A, Nedeljkovic I, Amin N, van Diemen CC, Brusselle GG, Bossé Y, Brandsma CA, Hao K, Paré PD, van Duijn CM, Postma DS, Boezen HM., Free PMC Article | 07/20/2019 |
| NF-YC was significantly increased in gliomas. Knockdown of NF-YC reduced brain tumor size in vivo. NF-YC played as an independent predictor of patient survival. | NF-YC in glioma cell proliferation and tumor growth and its role as an independent predictor of patient survival.
Cui H, Zhang M, Wang Y, Wang Y. | 07/29/2017 |
| p53 negatively regulates the expression of the PRR11-SKA2 bidirectional transcription unit through NF-Y, suggesting that the inability to repress the PRR11-SKA2 bidirectional transcription unit after loss of p53 might contribute to tumorigenesis. | The PRR11-SKA2 Bidirectional Transcription Unit Is Negatively Regulated by p53 through NF-Y in Lung Cancer Cells.
Wang Y, Weng H, Zhang Y, Long Y, Li Y, Niu Y, Song F, Bu Y., Free PMC Article | 04/22/2017 |
| Presence of NF-Y transcription factor plays a pivotal role in transcriptional regulation of ID genes in development. | Epigenetic role of CCAAT box-binding transcription factor NF-Y on ID gene family in human embryonic carcinoma cells.
Moeinvaziri F, Shahhoseini M. | 10/22/2016 |
| TAF12 and NFYC are transcription factors that regulate the epigenome, whereas RAD54L plays a central role in DNA repair | Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes.
Tong Y, Merino D, Nimmervoll B, Gupta K, Wang YD, Finkelstein D, Dalton J, Ellison DW, Ma X, Zhang J, Malkin D, Gilbertson RJ., Free PMC Article | 07/25/2015 |
| the expression of the adipogenic differentiation genes fatty acid binding protein-4, adiponectin, and leptin and the formation of fat droplets were impaired. | Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells.
Mitterberger MC, Lechner S, Mattesich M, Zwerschke W. | 02/8/2014 |
| NFY-C expression was elevated in colorectal adenocarcinomas; moreover, NFY-C mRNA levels correlated with time to disease progression, while NFY-C protein expression was significantly higher in metastatic disease | Altered expression of NFY-C and RORA in colorectal adenocarcinomas.
Kottorou AE, Antonacopoulou AG, Dimitrakopoulos FI, Tsamandas AC, Scopa CD, Petsas T, Kalofonos HP. | 06/15/2013 |
| The crystal structure of NF-Y bound to a 25 bp CCAAT oligonucleotide shows that the histone-fold domains dimer binds to the DNA sugar-phosphate backbone, mimicking the nucleosome H2A/H2B-DNA assembly; NF-YA both binds to NF-YB/NF-YC and inserts an alpha helix deeply into the DNA minor groove, providing sequence-specific contacts to the CCAAT box. | Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination.
Nardini M, Gnesutta N, Donati G, Gatta R, Forni C, Fossati A, Vonrhein C, Moras D, Romier C, Bolognesi M, Mantovani R. | 03/23/2013 |
| Sp1, NF-Y and FOXO transcription factors are involved in the regulation of LKB1 transcription. | Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors.
Lützner N, De-Castro Arce J, Rösl F., Free PMC Article | 08/4/2012 |
| NF-YC functions as a new corepressor of agonist-bound mineralocorticoid receptor via alteration of aldosterone-induced MR conformation | NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor.
Murai-Takeda A, Shibata H, Kurihara I, Kobayashi S, Yokota K, Suda N, Mitsuishi Y, Jo R, Kitagawa H, Kato S, Saruta T, Itoh H., Free PMC Article | 04/19/2010 |
| NF-YC complexity is generated by dual promoters and alternative splicing | NF-YC complexity is generated by dual promoters and alternative splicing.
Ceribelli M, Benatti P, Imbriano C, Mantovani R., Free PMC Article | 01/21/2010 |
| Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple neoplasms. | Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers.
Yamanaka K, Mizuarai S, Eguchi T, Itadani H, Hirai H, Kotani H. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesGenetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).
Campa D, Hüsing A, Chang-Claude J, Dostal L, Boeing H, Kröger J, Tjønneland A, Roswall N, Overvad K, Dahm CC, Rodríguez L, Sala N, Pérez MJ, Larrañaga N, Chirlaque MD, Ardanaz E, Khaw KT, Wareham N, Allen NE, Travis RC, Trichopoulou A, Naska A, Bamia C, Palli D, Sieri S, Tumino R, Sacerdote C, van Kranen HJ, Bas Bueno-de-Mesquita H, Stattin P, Johansson M, Chajes V, Rinaldi S, Romieu I, Siddiq A, Norat T, Riboli E, Kaaks R, Canzian F. Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.
Ichikawa S, Koller DL, Padgett LR, Lai D, Hui SL, Peacock M, Foroud T, Econs MJ. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.
Horikawa Y, Wood CG, Yang H, Zhao H, Ye Y, Gu J, Lin J, Habuchi T, Wu X. | 01/11/2009 |
| The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y. | The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y.
Romier C, Cocchiarella F, Mantovani R, Moras D. | 01/21/2010 |
| role in repressing Smad2 and Smad3 transactivating activity | Repression of Smad2 and Smad3 transactivating activity by association with a novel splice variant of CCAAT-binding factor C subunit.
Chen F, Ogawa K, Liu X, Stringfield TM, Chen Y., Free PMC Article | 01/21/2010 |
| p300 binds to multiple NF-Y trimers to regulate cyclin B2 promoter function | Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function.
Salsi V, Caretti G, Wasner M, Reinhard W, Haugwitz U, Engeland K, Mantovani R. | 01/21/2010 |
| C/EBPbeta contributes to the induction of hepatocyte replication in response to HGF in rodents, which is likely due to post-translational modifications. | C/EBPbeta contributes to hepatocyte growth factor-induced replication of rodent hepatocytes.
Wang B, Gao C, Ponder KP. | 01/21/2010 |
| Histone deacetylase inhibitors can induce Gadd45 through its promoter without the need for functional p53, and both Oct-1 and NF-Y concertedly participate in trichostatin A-induced activation of the gadd45 promoter. | p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y.
Hirose T, Sowa Y, Takahashi S, Saito S, Yasuda C, Shindo N, Furuichi K, Sakai T. | 01/21/2010 |