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    NMB neuromedin B [ Homo sapiens (human) ]

    Gene ID: 4828, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    GPNMB is exposed on the surface of dormant breast cancer cells and its activity contributes to the acquisition of stem cell-like properties

    Glycoprotein nmb Is Exposed on the Surface of Dormant Breast Cancer Cells and Induces Stem Cell-like Properties.
    Chen C, Okita Y, Watanabe Y, Abe F, Fikry MA, Ichikawa Y, Suzuki H, Shibuya A, Kato M.

    10/12/2019
    Genetic clues to the mechanism by which MC4R, FTO, and NMB influences changes in BMI and obesity.

    Effects of MC4R, FTO, and NMB gene variants to obesity, physical activity, and eating behavior phenotypes.
    Kirac D, Kasimay Cakir O, Avcilar T, Deyneli O, Kurtel H, Yazici D, Kaspar EC, Celik N, Guney AI.

    08/12/2017
    Rs2292462 was associated with left ventricular hypertrophy in type 2 diabetic patients.

    Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis.
    Parry HM, Donnelly LA, Van Zuydam N, Doney AS, Elder DH, Morris AD, Struthers AD, Palmer CN, Lang CC, Wellcome Trust Case Control Consortium 2., Free PMC Article

    11/30/2013
    There was no association between eating behaviour traits, or anthropometric variables, and NMB p.P73T polymorphism.

    Effects of neuromedin-β on caloric compensation, eating behaviours and habitual food intake.
    Blanchet R, Lemieux S, Couture P, Bouchard L, Vohl MC, Pérusse L.

    10/29/2011
    TT genotype of the NMB rs3809508 polymorphism was associated with a higher risk of obesity and moreover, the effects of this polymorphism on anthropometric values were influenced by the maternal educational level.

    Influence of maternal educational level on the association between the rs3809508 neuromedin B gene polymorphism and the risk of obesity in the HELENA study.
    Pigeyre M, Bokor S, Romon M, Gottrand F, Gilbert CC, Valtueña J, Gómez-Martínez S, Moreno LA, Amouyel P, Dallongeville J, Meirhaeghe A, HELENA Study group, Pigeyre M, Bokor S, Romon M, Gottrand F, Gilbert CC, Valtueña J, Gómez-Martínez S, Moreno LA, Amouyel P, Dallongeville J, Meirhaeghe A, HELENA Study group.

    11/6/2010
    Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Influence of maternal educational level on the association between the rs3809508 neuromedin B gene polymorphism and the risk of obesity in the HELENA study.
    Pigeyre M, Bokor S, Romon M, Gottrand F, Gilbert CC, Valtueña J, Gómez-Martínez S, Moreno LA, Amouyel P, Dallongeville J, Meirhaeghe A, HELENA Study group, Pigeyre M, Bokor S, Romon M, Gottrand F, Gilbert CC, Valtueña J, Gómez-Martínez S, Moreno LA, Amouyel P, Dallongeville J, Meirhaeghe A, HELENA Study group.

    01/20/2010
    No significant differences in the genotype distribution were demonstrated between normal weight and overweight/obese subjects

    Neuromedin beta: P73T polymorphism in overweight and obese subjects.
    Spálová J, Zamrazilová H, Vcelák J, Vaňková M, Lukášová P, Hill M, Hlavatá K, Šrámková P, Fried M, Aldhoon B, Kunešová M, Bendlová B, Hainer V, Spálová J, Zamrazilová H, Vcelák J, Vaňková M, Lukášová P, Hill M, Hlavatá K, Šrámková P, Fried M, Aldhoon B, Kunešová M, Bendlová B, Hainer V.

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (2) articles

    Neuromedin beta: P73T polymorphism in overweight and obese subjects.
    Spálová J, Zamrazilová H, Vcelák J, Vaňková M, Lukášová P, Hill M, Hlavatá K, Šrámková P, Fried M, Aldhoon B, Kunešová M, Bendlová B, Hainer V, Spálová J, Zamrazilová H, Vcelák J, Vaňková M, Lukášová P, Hill M, Hlavatá K, Šrámková P, Fried M, Aldhoon B, Kunešová M, Bendlová B, Hainer V.

    Contribution of several candidate gene polymorphisms in the determination of adiposity changes: results from the Québec Family Study.
    Bouchard L, Tremblay A, Bouchard C, Pérusse L.

    03/13/2008
    Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)

    Significant association between a silent polymorphism in the neuromedin B gene and body weight in German children and adolescents.
    Oeffner F, Bornholdt D, Ziegler A, Hinney A, Görg T, Gerber G, Goldschmidt HP, Siegfried W, Wright A, Hebebrand J, Grzeschik KH.

    03/13/2008
    REsults describe the expression of neuromedin B in adipose tissue and its regulation by changes in energy balance.

    Expression of neuromedin B in adipose tissue and its regulation by changes in energy balance.
    Hoggard N, Bashir S, Cruickshank M, Miller JD, Speakman JR.

    01/21/2010
    lysosomal degradation of neuromedin B is dependent on tripeptidyl peptidase-I

    The lysosomal degradation of neuromedin B is dependent on tripeptidyl peptidase-I: evidence for the impairment of neuropeptide degradation in late-infantile neuronal ceroid lipofuscinosis.
    Kopan S, Sivasubramaniam U, Warburton MJ.

    01/21/2010
    NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells.

    Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon.
    Matusiak D, Glover S, Nathaniel R, Matkowskyj K, Yang J, Benya RV.

    01/21/2010
    Associated with eating behaviors

    Neuromedin beta: a strong candidate gene linking eating behaviors and susceptibility to obesity.
    Bouchard L, Drapeau V, Provencher V, Lemieux S, Chagnon Y, Rice T, Rao DC, Vohl MC, Tremblay A, Bouchard C, Pérusse L.

    01/21/2010
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