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    NOS1 nitric oxide synthase 1 [ Homo sapiens (human) ]

    Gene ID: 4842, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The neuronal nitric oxide synthase expression increases during satellite cell-derived primary myoblasts differentiation.

    The neuronal nitric oxide synthase expression increases during satellite cell-derived primary myoblasts differentiation.
    Kusano M, Sakai K, Tomiga Y, Ito A, Nakashima S, Uehara Y, Kawanaka K, Kitajima Y, Higaki Y.

    01/4/2024
    nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity.

    nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity.
    Biojone C, C Casarotto P, Cannarozzo C, Fred SM, Herrera-Rodríguez R, Lesnikova A, Voipio M, Castrén E.

    03/1/2023
    The expanding roles of neuronal nitric oxide synthase (NOS1).

    The expanding roles of neuronal nitric oxide synthase (NOS1).
    Solanki K, Rajpoot S, Bezsonov EE, Orekhov AN, Saluja R, Wary A, Axen C, Wary K, Baig MS., Free PMC Article

    02/14/2023
    The Role of Macula Densa Nitric Oxide Synthase 1 Beta Splice Variant in Modulating Tubuloglomerular Feedback.

    The Role of Macula Densa Nitric Oxide Synthase 1 Beta Splice Variant in Modulating Tubuloglomerular Feedback.
    Liu R, Juncos LA, Lu Y, Wei J, Zhang J, Wang L, Lai EY, Carlstrom M, Persson AEG., Free PMC Article

    02/4/2023
    NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice.

    NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice.
    Chachlaki K, Messina A, Delli V, Leysen V, Maurnyi C, Huber C, Ternier G, Skrapits K, Papadakis G, Shruti S, Kapanidou M, Cheng X, Acierno J, Rademaker J, Rasika S, Quinton R, Niedziela M, L'Allemand D, Pignatelli D, Dirlewander M, Lang-Muritano M, Kempf P, Catteau-Jonard S, Niederländer NJ, Ciofi P, Tena-Sempere M, Garthwaite J, Storme L, Avan P, Hrabovszky E, Carleton A, Santoni F, Giacobini P, Pitteloud N, Prevot V., Free PMC Article

    10/15/2022
    Functional Roles of Neuronal Nitric Oxide Synthase in Neurodegenerative Diseases and Mood Disorders.

    Functional Roles of Neuronal Nitric Oxide Synthase in Neurodegenerative Diseases and Mood Disorders.
    Poon CH, Tsui KC, Chau SC, Chong PS, Lui SWY, Aquili L, Wong KH, Lim LW.

    07/2/2022
    Uncovering associations between mental illness diagnosis, nitric oxide synthase gene variation, and peripheral nitric oxide concentration.

    Uncovering associations between mental illness diagnosis, nitric oxide synthase gene variation, and peripheral nitric oxide concentration.
    McNeill RV, Kehrwald C, Brum M, Knopf K, Brunkhorst-Kanaan N, Etyemez S, Koreny C, Bittner RA, Freudenberg F, Herterich S, Reif A, Kittel-Schneider S.

    05/7/2022
    Differences of Transport Activity of Arginine and Regulation on Neuronal Nitric Oxide Synthase and Oxidative Stress in Amyotrophic Lateral Sclerosis Model Cell Lines.

    Differences of Transport Activity of Arginine and Regulation on Neuronal Nitric Oxide Synthase and Oxidative Stress in Amyotrophic Lateral Sclerosis Model Cell Lines.
    Latif S, Kang YS., Free PMC Article

    01/22/2022
    The KiNG of reproduction: Kisspeptin/ nNOS interactions shaping hypothalamic GnRH release.

    The KiNG of reproduction: Kisspeptin/ nNOS interactions shaping hypothalamic GnRH release.
    Delli V, Silva MSB, Prévot V, Chachlaki K.

    12/25/2021
    Hypoxia-induced expression of neuronal nitric oxide synthase in astrocytes of human corpus callosum.

    Hypoxia-induced expression of neuronal nitric oxide synthase in astrocytes of human corpus callosum.
    Lorenzi T, Sagrati A, Montanari E, Senzacqua M, Morroni M, Fabri M.

    12/4/2021
    NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis.

    NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis.
    Ronchi C, Bernardi J, Mura M, Stefanello M, Badone B, Rocchetti M, Crotti L, Brink P, Schwartz PJ, Gnecchi M, Zaza A., Free PMC Article

    12/4/2021
    NOS1-mediated macrophage and endothelial cell interaction in the progression of atherosclerosis.

    NOS1-mediated macrophage and endothelial cell interaction in the progression of atherosclerosis.
    Roy A, Saqib U, Baig MS.

    11/27/2021
    Association of G84A and C276T polymorphism in neuronal nitric oxide synthase (nNOS) gene with herpes simplex encephalitis in eastern Indian population.

    Association of G84A and C276T polymorphism in neuronal nitric oxide synthase (nNOS) gene with herpes simplex encephalitis in eastern Indian population.
    Rathore SK, Pati P, Priyadarshini S, Dwibedi B.

    10/16/2021
    nNOS induction and NOSIP interaction impact granulopoiesis and neutrophil differentiation by modulating nitric oxide generation.

    nNOS induction and NOSIP interaction impact granulopoiesis and neutrophil differentiation by modulating nitric oxide generation.
    Sadaf S, Nagarkoti S, Awasthi D, Singh AK, Srivastava RN, Kumar S, Barthwal MK, Dikshit M.

    10/2/2021
    The Functional Diversity of Nitric Oxide Synthase Isoforms in Human Nose and Paranasal Sinuses: Contrasting Pathophysiological Aspects in Nasal Allergy and Chronic Rhinosinusitis.

    The Functional Diversity of Nitric Oxide Synthase Isoforms in Human Nose and Paranasal Sinuses: Contrasting Pathophysiological Aspects in Nasal Allergy and Chronic Rhinosinusitis.
    Kawasumi T, Takeno S, Ishikawa C, Takahara D, Taruya T, Takemoto K, Hamamoto T, Ishino T, Ueda T., Free PMC Article

    08/21/2021
    Hepatic nNOS impaired hepatic insulin sensitivity through the activation of p38 MAPK.

    Hepatic nNOS impaired hepatic insulin sensitivity through the activation of p38 MAPK.
    Zhao T, Li Q, Mao Q, Mu K, Wang C.

    07/24/2021
    Nitric oxide synthase genotype interacts with stressful life events to increase aggression in male subjects in a population-representative sample.

    Nitric oxide synthase genotype interacts with stressful life events to increase aggression in male subjects in a population-representative sample.
    O'Leary A, Laas K, Vaht M, Kiive E, Veidebaum T, Reif A, Harro J.

    04/24/2021
    Estimation of varicocele associated human ARG2 and NOS1 proteins and computational analysis on the effect of its nsSNPs.

    Estimation of varicocele associated human ARG2 and NOS1 proteins and computational analysis on the effect of its nsSNPs.
    Karthikeyan V, Vickram AS, Manian R.

    04/13/2021
    Neural correlates of NOS1 ex1f-VNTR allelic variation in panic disorder and agoraphobia during fear conditioning and extinction in fMRI.

    Neural correlates of NOS1 ex1f-VNTR allelic variation in panic disorder and agoraphobia during fear conditioning and extinction in fMRI.
    Ridderbusch IC, Yang Y, Weber H, Reif A, Herterich S, Ströhle A, Pfleiderer B, Arolt V, Wittchen HU, Lueken U, Kircher T, Straube B., Free PMC Article

    03/13/2021
    Oxidative Stress Orchestrates MAPK and Nitric-Oxide Synthase Signal.

    Oxidative Stress Orchestrates MAPK and Nitric-Oxide Synthase Signal.
    Takata T, Araki S, Tsuchiya Y, Watanabe Y., Free PMC Article

    03/6/2021
    Pyroptotic and apoptotic cell death in iNOS and nNOS overexpressing K562 cells: A mechanistic insight.

    Pyroptotic and apoptotic cell death in iNOS and nNOS overexpressing K562 cells: A mechanistic insight.
    Sadaf S, Awasthi D, Singh AK, Nagarkoti S, Kumar S, Barthwal MK, Dikshit M.

    10/31/2020
    High islet expression of nNOS in the type 2 diabetes patients.

    Expression levels of enzymes generating NO and CO in islets of murine and human diabetes.
    Mohammed Al-Amily I, Lundquist I, Salehi A.

    07/25/2020
    NOS1 has a role suppressing apoptosis in colon cancer cells through increasing SIRT3 activity

    Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
    Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, Huang M, Gao W, Chen J, Zhang Q, Zhong Z, Liu Q.

    07/11/2020
    Study provides evidence that NOS1 induces dysfunctional IFN signaling to promote lung metastasis in melanoma, highlighting NOS1-induced S-nitrosylation of HDAC2 in the regulation of IFN signaling via histone modification.

    NOS1 inhibits the interferon response of cancer cells by S-nitrosylation of HDAC2.
    Xu P, Ye S, Li K, Huang M, Wang Q, Zeng S, Chen X, Gao W, Chen J, Zhang Q, Zhong Z, Lin Y, Rong Z, Xu Y, Hao B, Peng A, Ouyang M, Liu Q., Free PMC Article

    06/6/2020
    nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis in humans and mice.

    nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis.
    Montagna C, Rizza S, Cirotti C, Maiani E, Muscaritoli M, Musarò A, Carrí MT, Ferraro E, Cecconi F, Filomeni G., Free PMC Article

    05/16/2020
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