Single nucleotide polymorphism of Notch1 gene rs3124599 allele is associated with the severity of CVA6-related HFMD in the Chinese Han population.
Li Z, Ji W, Dai B, Chen S, Wang F, Duan G, Jin Y., Free PMC Article

Jagged1-Notch1 Signaling Pathway Induces M1 Microglia to Disrupt the Barrier Function of Retinal Microvascular Endothelial Cells.
Wu X, Zhu H, Liu J, Ouyang S, Lyu Z, Jin Y, Chen X, Meng Q.

Notch1 signaling pathway promotes growth and metastasis of gastric cancer via modulating CDH5.
Zhou L, Yang Y, Ye Y, Qiao Q, Mi Y, Liu H, Zheng Y, Wang Y, Liu M, Zhou Y., Free PMC Article

Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma.
Zhao J, Williams MD, Hernandez M, Kuang G, Goldberg H, Fan J, Ning J, Ferrarotto R, Esmaeli B., Free PMC Article

Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis.
Mora P, Laisné M, Bourguignon C, Rouault P, Jaspard-Vinassa B, Maître M, Gadeau AP, Renault MA, Horng S, Couffinhal T, Chapouly C., Free PMC Article

ALYREF promotes the metastasis of nasopharyngeal carcinoma by increasing the stability of NOTCH1 mRNA.
Jin Y, Yao J, Fu J, Huang Q, Luo Y, You Y, Zhang W, Zhong Q, Xia T, Xia L., Free PMC Article

TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Wang G, Wu Y, Su Y, Qu N, Chen B, Zhou D, Yuan L, Yin M, Liu M, Zhou W., Free PMC Article

Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma.
Chen Y, Weng X, Zhang C, Wang S, Wu X, Cheng B., Free PMC Article

Genetic variation in NOTCH1 is associated with overweight and obesity in Brazilian elderly.
Silva Barcelos EC, Naslavsky MS, Fernandes IS, Scliar MO, Yamamoto GL, Wang JYT, Bride L, de Sousa VP, Pimassoni LHS, Sportoletti P, de Paula F, von Zeidler SV, Duarte YAO, Passos-Bueno MR, Zatz M, Errera FIV., Free PMC Article

Expanding the phenotypic spectrum of NOTCH1 variants: clinical manifestations in families with congenital heart disease.
Stanley KJ, Kalbfleisch KJ, Moran OM, Chaturvedi RR, Roifman M, Chen X, Manshaei R, Martin N, McDermott S, McNiven V, Myles-Reid D, Nield LE, Reuter MS, Schwartz MLB, Shannon P, Silver R, Somerville C, Teitelbaum R, Zahavich L, Bassett AS, Kim RH, Mital S, Chitayat D, Jobling RK., Free PMC Article

Analysis of endogenous NOTCH1 from POFUT1 S162L patient fibroblasts reveals the importance of the O-fucose modification on EGF12 in human development.
Matsumoto K, Luther KB, Haltiwanger RS.,

Role of Mutation of NOTCH1 gene in development of oral squamous cell carcinoma: a narrative review.
Javaid Q, Usmani A.

ZEB2 alleviates Hirschsprung's-associated enterocolitis by promoting the proliferation and differentiation of enteric neural precursor cells via the Notch-1/Jagged-2 pathway.
Feng Y, Zhou C, Zhao F, Ma T, Xiao Y, Peng K, Xia R.

Analysis of Notch1 protein expression in methotrexate-associated lymphoproliferative disorders.
Okatani T, Nishimura MF, Egusa Y, Yoshida S, Nishimura Y, Nishikori A, Yoshino T, Yamamoto H, Sato Y., Free PMC Article

NOTCH1-Related Leukoencephalopathy: A Novel Variant and Literature Review.
Della Vecchia S, Tessa A, Pasquariello R, Seabra L, Crow YJ, Battini R., Free PMC Article

N6-Methyladenosine Reader YTHDF1 Promotes Stemness and Therapeutic Resistance in Hepatocellular Carcinoma by Enhancing NOTCH1 Expression.
Zhang X, Su T, Wu Y, Cai Y, Wang L, Liang C, Zhou L, Wang S, Li XX, Peng S, Kuang M, Yu J, Xu L.

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.
Chan TS, Cheng LH, Hsu CC, Yang PM, Liao TY, Hsieh HY, Lin PC, HuangFu WC, Chuu CP, Tsai KK., Free PMC Article

Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1.
Zhang HL, Li N, Dong L, Ma HX, Yang MC.

FBP1 inhibits NSCLC stemness by promoting ubiquitination of Notch1 intracellular domain and accelerating degradation.
He T, Wang Y, Lv W, Wang Y, Li X, Zhang Q, Shen HM, Hu J., Free PMC Article

NOTCH1 and CREBBP co-mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR-mutated NSCLC: translational research of phase III IMPACT study.
Ikeda S, Tsuboi M, Sakai K, Misumi T, Akamatsu H, Shoda H, Sakakura N, Nakamura A, Ohde Y, Hayashi H, Okishio K, Okada M, Yoshino I, Okami J, Takahashi K, Ikeda N, Tanahashi M, Tambo Y, Saito H, Toyooka S, Inokawa H, Chen-Yoshikawa T, Yokoyama T, Okamoto T, Yanagitani N, Oki M, Takahama M, Sawa K, Tada H, Nakagawa K, Mitsudomi T, Nishio K., Free PMC Article

Macrophage-specific deletion of Notch-1 induced M2 anti-inflammatory effect in atherosclerosis via activation of the PI3K-oxidative stress axis.
Zhang M, Yue X, Zhao X, Lu Y, Liu H, Zhang Z, Ma H, Wang X, Xing H., Free PMC Article

IMMUNOPHENOTYPE OF LEUKEMIC CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS WITH NOTCH1 AND SF3B1 GENE MUTATIONS.
Golyarnik N, Абраменко І, Movchan G, Martina Z, Dyagil I, Chumak A, Bazyka D.

The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis.
Padovano C, Bianco SD, Sansico F, De Santis E, Tamiro F, Colucci M, Totti B, Di Iasio S, Bruno G, Panelli P, Miscio G, Mazza T, Giambra V., Free PMC Article

Single-cell sequencing reveals SATB2/NOTCH1 signaling promotes the progression of malignancy of epithelial cells from papillary thyroid cancer.
Zhang W, Wang J, Huang D, Liu Z, Lu T, Cui C, Li Z.

Targeting Inhibition of Notch 1 Can Promote mTOR Signaling Pathway in Tumor-Related Macrophage to Regulate the Development of Ovarian Cancer.
Guo C, Mo J, Liu X, Chen Y, Liang L, Li H, Yang L.