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    NPPA natriuretic peptide A [ Homo sapiens (human) ]

    Gene ID: 4878, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Corin and Left Atrial Cardiomyopathy, Hypertension, Arrhythmia, and Fibrosis.

    Corin and Left Atrial Cardiomyopathy, Hypertension, Arrhythmia, and Fibrosis.
    Baris Feldman H, Chai Gadot C, Zahler D, Mory A, Aviram G, Elhanan E, Shefer G, Goldiner I, Amir Y, Kurolap A, Ablin JN.

    11/3/2023
    Atrial natriuretic peptide stimulates autophagy/mitophagy and improves mitochondrial function in chronic heart failure.

    Atrial natriuretic peptide stimulates autophagy/mitophagy and improves mitochondrial function in chronic heart failure.
    Raffa S, Forte M, Gallo G, Ranieri D, Marchitti S, Magrì D, Testa M, Stanzione R, Bianchi F, Cotugno M, Fiori E, Visco V, Sciarretta S, Volpe M, Rubattu S., Free PMC Article

    10/28/2023
    Sex-based differences in metabolic protection by the ANP genetic variant rs5068 in the general population.

    Sex-based differences in metabolic protection by the ANP genetic variant rs5068 in the general population.
    Ichiki T, Cannone V, Scott CG, Iyer SR, Sangaralingham SJ, Bailey KR, Goetze JP, Tsuji Y, Rodeheffer RJ, Burnett JC Jr., Free PMC Article

    08/10/2023
    Regulatory role of atrial natriuretic peptide in brown adipose tissue: A narrative review.

    Regulatory role of atrial natriuretic peptide in brown adipose tissue: A narrative review.
    Lu G, Hu R, Tao T, Hu M, Dong Z, Wang C.

    12/24/2022
    Serum Atrial Natriuretic Peptide, NPPA Promoter Methylation, and Cardiovascular Disease: A 10-year Follow-Up Study in Chinese Adults.

    Serum Atrial Natriuretic Peptide, NPPA Promoter Methylation, and Cardiovascular Disease: A 10-year Follow-Up Study in Chinese Adults.
    Chen L, Li J, Zhang M, Zhang Q, Wu L, Lu Y, He Y, Jiang J, Zhang X, Hu J, Ding Y, Zhang M, Peng H., Free PMC Article

    06/11/2022
    NPPA Promoter Hypomethylation Predicts Central Obesity Development: A Prospective Longitudinal Study in Chinese Adults.

    NPPA Promoter Hypomethylation Predicts Central Obesity Development: A Prospective Longitudinal Study in Chinese Adults.
    Li J, Zhu J, Zhang Q, Chen L, Ma S, Lu Y, Shen B, Zhang R, Zhang M, He Y, Wu L, Peng H., Free PMC Article

    05/7/2022
    Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC-derived atrial fibrillation model.

    Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC-derived atrial fibrillation model.
    Ly OT, Chen H, Brown GE, Hong L, Wang X, Han YD, Pavel MA, Sridhar A, Maienschein-Cline M, Chalazan B, Ong SG, Abdelhady K, Massad M, Rizkallah LE, Rehman J, Khetani SR, Darbar D., Free PMC Article

    04/23/2022
    Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer.

    Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer.
    Sun A, Sheng X, Tang J, Yu Z, Zhang J., Free PMC Article

    02/12/2022
    Atrial Natriuretic Peptide: Structure, Function, and Physiological Effects: A Narrative Review.

    Atrial Natriuretic Peptide: Structure, Function, and Physiological Effects: A Narrative Review.
    Rao S, Pena C, Shurmur S, Nugent K., Free PMC Article

    01/8/2022
    Copeptin, pro-atrial natriuretic peptide and pro-adrenomedullin as markers of hypoxic stress in patients with obstructive sleep apnea-a prospective intervention study.

    Copeptin, pro-atrial natriuretic peptide and pro-adrenomedullin as markers of hypoxic stress in patients with obstructive sleep apnea-a prospective intervention study.
    Karakioulaki M, Grendelmeier P, Strobel W, Schmid T, Jahn K, Grize L, Tamm M, Stolz D., Free PMC Article

    11/27/2021
    Plasma Atrial Natriuretic Peptide Responses to Salt-Loading in Salt-Sensitive and Salt-Resistant Normotensive and Hypertensive Nigerians.

    Plasma Atrial Natriuretic Peptide Responses to Salt-Loading in Salt-Sensitive and Salt-Resistant Normotensive and Hypertensive Nigerians.
    Abidoye O.

    11/6/2021
    Impact of Midregional N-Terminal Pro-Atrial Natriuretic Peptide and Soluble Suppression of Tumorigenicity 2 Levels on Heart Rhythm in Patients Treated With Catheter Ablation for Atrial Fibrillation: The Biorhythm Study.

    Impact of Midregional N-Terminal Pro-Atrial Natriuretic Peptide and Soluble Suppression of Tumorigenicity 2 Levels on Heart Rhythm in Patients Treated With Catheter Ablation for Atrial Fibrillation: The Biorhythm Study.
    Badoz M, Serzian G, Favoulet B, Sellal JM, De Chillou C, Hammache N, Laurent G, Mebazaa A, Ecarnot F, Bardonnet K, Seronde MF, Schiele F, Meneveau N., Free PMC Article

    10/30/2021
    Association between NPPA promoter methylation and hypertension: results from Gusu cohort and replication in an independent sample.

    Association between NPPA promoter methylation and hypertension: results from Gusu cohort and replication in an independent sample.
    Li J, Zhu J, Ren L, Ma S, Shen B, Yu J, Zhang R, Zhang M, He Y, Peng H., Free PMC Article

    10/30/2021
    MR-proANP, a cardiovascular biomarker to predict late-onset preeclampsia and intrauterine growth restricted fetuses.

    MR-proANP, a cardiovascular biomarker to predict late-onset preeclampsia and intrauterine growth restricted fetuses.
    Birdir C, Fox L, Droste L, Frank M, Fryze J, Enekwe A, Köninger A, Kimmig R, Schmidt B, Gellhaus A.

    08/14/2021
    T2238C atrial natriuretic peptide gene variant and cardiovascular events in patients with atrial fibrillation: A substudy from the ATHERO-AF cohort.

    T2238C atrial natriuretic peptide gene variant and cardiovascular events in patients with atrial fibrillation: A substudy from the ATHERO-AF cohort.
    Pastori D, Carnevale R, Stanzione R, Nocella C, Cotugno M, Marchitti S, Bianchi F, Forte M, Valenti V, Biondi-Zoccai G, Schiavon S, Vecchio D, Versaci F, Frati G, Violi F, Volpe M, Pignatelli P, Rubattu S, Sciarretta S.

    07/24/2021
    Mortality in cardiogenic shock is stronger associated to clinical factors than contemporary biomarkers reflecting neurohormonal stress and inflammatory activation.

    Mortality in cardiogenic shock is stronger associated to clinical factors than contemporary biomarkers reflecting neurohormonal stress and inflammatory activation.
    Josiassen J, Frydland M, Holmvang L, Lerche Helgestad OK, Okkels Jensen L, Goetze JP, Eifer Møller J, Hassager C.

    06/5/2021
    Plasma volume contraction reduces atrial natriuretic peptide after four days of hypobaric hypoxia exposure.

    Plasma volume contraction reduces atrial natriuretic peptide after four days of hypobaric hypoxia exposure.
    Gatterer H, Rauch S, Regli IB, Woyke S, Schlittler M, Turner R, Strapazzon G, Brugger H, Goetze JP, Feraille E, Siebenmann C.

    05/15/2021
    ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells.

    ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells.
    Mezzasoma L, Talesa VN, Romani R, Bellezza I., Free PMC Article

    04/3/2021
    Diagnostic utility of MR-proANP and NT-proBNP in elderly outpatients with a high risk of heart failure: the Copenhagen heart failure risk study.

    Diagnostic utility of MR-proANP and NT-proBNP in elderly outpatients with a high risk of heart failure: the Copenhagen heart failure risk study.
    Gaborit FS, Kistorp C, Kümler T, Hassager C, Tønder N, Iversen K, Hansen PM, Kamstrup PR, Faber J, Køber L, Schou M.

    01/16/2021
    Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP.

    Differential Regulation of ANP and BNP in Acute Decompensated Heart Failure: Deficiency of ANP.
    Reginauld SH, Cannone V, Iyer S, Scott C, Bailey K, Schaefer J, Chen Y, Sangaralingham SJ, Burnett JC Jr., Free PMC Article

    11/21/2020
    Antisense regulation of atrial natriuretic peptide expression.

    Antisense regulation of atrial natriuretic peptide expression.
    Celik S, Sadegh MK, Morley M, Roselli C, Ellinor PT, Cappola T, Smith JG, Gidlöf O., Free PMC Article

    10/24/2020
    Pro-atrial natriuretic peptide and pro-adrenomedullin before cardiac surgery in children. Can we predict the future?

    Pro-atrial natriuretic peptide and pro-adrenomedullin before cardiac surgery in children. Can we predict the future?
    Bobillo-Perez S, Girona-Alarcon M, Corniero P, Sole-Ribalta A, Balaguer M, Esteban E, Valls A, Jordan I, Cambra FJ., Free PMC Article

    09/26/2020
    Associations among NPPA gene polymorphisms, serum ANP levels, and hypertension in the Chinese Han population.

    Associations among NPPA gene polymorphisms, serum ANP levels, and hypertension in the Chinese Han population.
    Zhang H, Mo X, Zhou Z, Zhu Z, HuangFu X, Xu T, Wang A, Guo Z, Zhang Y.

    09/19/2020
    Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients.

    Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients.
    Yagmur E, Sckaer JH, Koek GH, Weiskirchen R, Trautwein C, Koch A, Tacke F., Free PMC Article

    09/12/2020
    A dual luciferase reporter assay showed that both SRF mutants (G274D and G294C) impaired SRF transcriptional activity at the SRF promoter and atrial natriuretic factor (ANF) promoter (p < 0.05), additionally, the mutants displayed reduced synergism with GATA4. These results suggest that SRF-p.G274D and SRF-p.G294C may have potential pathogenic effects.

    Novel mutations of the SRF gene in Chinese sporadic conotruncal heart defect patients.
    Mengmeng X, Yuejuan X, Sun C, Yanan L, Fen L, Kun S., Free PMC Article

    07/18/2020
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