| miR-148a-3p regulates proliferation and apoptosis of idiopathic gingival fibroma by targeting NPTX1. | miR-148a-3p regulates proliferation and apoptosis of idiopathic gingival fibroma by targeting NPTX1.
Sun Y, Xie L, Ren X, Ran L, He H, Kong F, Yang S, Zhang M. | 09/23/2024 |
| Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease. | Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease.
Warth Perez Arias CC, Silbern I, Caldi Gomes L, Wartmann H, Dambeck V, Fanz J, Neuenroth L, Bähr M, Outeiro TF, Bonn S, Stadelmann-Nessler C, Rizzoli SO, Lenz C, Urlaub H, Lingor P. | 08/30/2023 |
| NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia. | NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia.
Coutelier M, Jacoupy M, Janer A, Renaud F, Auger N, Saripella GV, Ancien F, Pucci F, Rooman M, Gilis D, Larivière R, Sgarioto N, Valter R, Guillot-Noel L, Le Ber I, Sayah S, Charles P, Nümann A, Pauly MG, Helmchen C, Deininger N, Haack TB, Brais B, Brice A, Trégouët DA, El Hachimi KH, Shoubridge EA, Durr A, Stevanin G. | 06/11/2022 |
| Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells. | Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells.
Vial R, Poitevin S, McKay N, Burtey S, Cerini C., Free PMC Article | 03/26/2022 |
| Downregulation of NPTX1 induces cell cycle progression through Wnt/beta-catenin signaling in breast cancer. | Downregulation of NPTX1 induces cell cycle progression through Wnt/β-catenin signaling in breast cancer.
Ye RY, Kuang XY, Shao N, Wang SM, Lin Y. | 09/4/2021 |
| MiR-4295 facilitates cell proliferation and metastasis in head and neck squamous cell carcinoma by targeting NPTX1. | MiR-4295 facilitates cell proliferation and metastasis in head and neck squamous cell carcinoma by targeting NPTX1.
Lu S, Zhou C, Zou B, Zhang H, Feng M. | 01/9/2021 |
| Findings indicate that neuronal pentraxin 1 (NPTX1) is a potential clinical therapeutic target. | As a downstream target of the AKT pathway, NPTX1 inhibits proliferation and promotes apoptosis in hepatocellular carcinoma.
Zhao Y, Yu Y, Zhao W, You S, Feng M, Xie C, Chi X, Zhang Y, Wang X., Free PMC Article | 08/13/2020 |
| Relative to normal elderly, plasma NP1 was elevated in patients with mild cognitive impairment and elevated further in the subset that progressed to early-stage Alzheimer's disease. | Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease.
Ma QL, Teng E, Zuo X, Jones M, Teter B, Zhao EY, Zhu C, Bilousova T, Gylys KH, Apostolova LG, LaDu MJ, Hossain MA, Frautschy SA, Cole GM., Free PMC Article | 09/7/2019 |
| NPTX1 is down-regulated in colon cancer. In addition, NPTX1 inhibits the proliferation of colon cancer cells via decreasing cyclin A2 and CDK2. | NPTX1 inhibits colon cancer cell proliferation through down-regulating cyclin A2 and CDK2 expression.
Peng X, Pan K, Zhao W, Zhang J, Yuan S, Wen X, Zhou W, Yu Z. | 09/15/2018 |
| NPTX1 was significantly associated with bipolar disorder. | Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder.
Rajkumar AP, Christensen JH, Mattheisen M, Jacobsen I, Bache I, Pallesen J, Grove J, Qvist P, McQuillin A, Gurling HM, Tümer Z, Mors O, Børglum AD. | 04/23/2016 |
| findings suggest that lower NARP mRNA expression contributes to lower excitatory drive onto parvalbumin interneurons in schizophrenia. | Altered Markers of Cortical γ-Aminobutyric Acid Neuronal Activity in Schizophrenia: Role of the NARP Gene.
Kimoto S, Zaki MM, Bazmi HH, Lewis DA., Free PMC Article | 10/31/2015 |
| These results suggest that NPTX1 hypermethylation and consequent mRNA changes might be an important molecular mechanism in lung cancer. | NPTX1 is a novel epigenetic regulation gene and associated with prognosis in lung cancer.
Zhou C, Qin Y, Xie Z, Zhang J, Yang M, Li S, Chen R. | 05/2/2015 |
| Taken together, these results demonstrate that NP1 gene is a target of as hypoxia inducible factor-1 alpha and it regulates NP1 expression by binding to hypoxia responsive elements in its promoter region. | Neuronal pentraxin 1 expression is regulated by hypoxia inducible factor-1α.
Botlagunta M. | 03/21/2015 |
| Long acting progestin contraceptive-enhanced NPTX1 secretion and reactive oxygen species generation in endometrial stromal cells impair endometrial endothelial cells survival resulting in a loss in vascular integrity. | Long-acting progestin-only contraceptives enhance human endometrial stromal cell expressed neuronal pentraxin-1 and reactive oxygen species to promote endothelial cell apoptosis.
Guzeloglu-Kayisli O, Basar M, Shapiro JP, Semerci N, Huang JS, Schatz F, Lockwood CJ, Kayisli UA., Free PMC Article | 01/24/2015 |
| Neuronal pentraxin 1 transgene is a key factor for the synapse loss, the neurite damage, and the apoptotic neuronal death evoked by amyloid-beta protein, which regulates NP1 expression. | Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain.
Abad MA, Enguita M, DeGregorio-Rocasolano N, Ferrer I, Trullas R., Free PMC Article | 01/21/2010 |
| The purpose of the present study was to assess the toxic effect of taipoxin in SCLC-cell lines and to determine if toxicity correlates to NPR and NP1 and NP2 expression levels. | Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin.
Poulsen TT, Pedersen N, Perin MS, Hansen CK, Poulsen HS. | 08/16/2006 |