[Genetic analysis of a Chinese pedigree affected with Brachydactyly type B1 due to a novel variant of ROR2 gene]. | [Genetic analysis of a Chinese pedigree affected with Brachydactyly type B1 due to a novel variant of ROR2 gene]. Ren H, Zhao W, Jiang N, Li S. | 04/30/2024 |
ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons. | ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons. Kuroda T, Yasuda S, Matsuyama S, Miura T, Sawada R, Matsuyama A, Yamamoto Y, Morioka MS, Kawaji H, Kasukawa T, Itoh M, Akutsu H, Kawai J, Sato Y., Free PMC Article | 01/10/2024 |
ROR2 deficit may induce the tetralogy of Fallot via down-regulating of beta-catenin/SOX3/HSPA6 in vitro and in vivo. | ROR2 deficit may induce the tetralogy of Fallot via down-regulating of β-catenin/SOX3/HSPA6 in vitro and in vivo. Guo R, Guo YZ, Zhou Q, Li G, Du Z, Shi Y, Xing Q., Free PMC Article | 12/20/2023 |
Expression of Wnt5a and ROR2, Components of the Noncanonical Wnt-Signaling Pathway, is Associated with Tumor Differentiation in Hepatocellular Carcinoma. | Expression of Wnt5a and ROR2, Components of the Noncanonical Wnt-Signaling Pathway, is Associated with Tumor Differentiation in Hepatocellular Carcinoma. Wakizaka K, Kamiyama T, Kakisaka T, Orimo T, Nagatsu A, Aiyama T, Shichi S, Taketomi A., Free PMC Article | 12/16/2023 |
Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2. | Cancer-associated fibroblasts influence Wnt/PCP signaling in gastric cancer cells by cytoneme-based dissemination of ROR2. Rogers S, Zhang C, Anagnostidis V, Liddle C, Fishel ML, Gielen F, Scholpp S., Free PMC Article | 09/22/2023 |
Downregulation of ROR2 attenuates LPS-induced A549 cell injury through JNK and ERK signaling pathways. | Downregulation of ROR2 attenuates LPS-induced A549 cell injury through JNK and ERK signaling pathways. Wang Z, Yang L., Free PMC Article | 05/8/2023 |
WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma. | WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma. Coupe N, Guo L, Bridges E, Campo L, Espinosa O, Colling R, Marshall A, Nandakumar A, van Stiphout R, Buffa FM, Corrie PG, Middleton MR, Macaulay VM., Free PMC Article | 04/14/2023 |
Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer. | Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer. Sanada M, Yamazaki M, Yamada T, Fujino K, Kudoh S, Tenjin Y, Saito H, Kudo N, Sato Y, Matsuo A, Suzuki M, Ito T. | 01/14/2023 |
Noncanonical Wnt/Ror2 signaling regulates cell-matrix adhesion to prompt directional tumor cell invasion in breast cancer. | Noncanonical Wnt/Ror2 signaling regulates cell-matrix adhesion to prompt directional tumor cell invasion in breast cancer. Si H, Zhao N, Pedroza A, Zaske AM, Rosen JM, Creighton CJ, Roarty K., Free PMC Article | 09/24/2022 |
Phenotypic and mutational spectrum of ROR2-related Robinow syndrome. | Phenotypic and mutational spectrum of ROR2-related Robinow syndrome. Lima AR, Ferreira BM, Zhang C, Jolly A, Du H, White JJ, Dawood M, Lins TC, Chiabai MA, van Beusekom E, Cordoba MS, Caldas Rosa ECC, Kayserili H, Kimonis V, Wu E, Mellado C, Aggarwal V, Richieri-Costa A, Brunoni D, Canó TM, Jorge AAL, Kim CA, Honjo R, Bertola DR, Dandalo-Girardi RM, Bayram Y, Gezdirici A, Yilmaz-Gulec E, Gumus E, Yilmaz GC, Okamoto N, Ohashi H, Coban-Akdemir Z, Mitani T, Jhangiani SN, Muzny DM, Regattieri NAP, Pogue R, Pereira RW, Otto PA, Gibbs RA, Ali BR, van Bokhoven H, Brunner HG, Sutton VR, Lupski JR, Vianna-Morgante AM, Carvalho CMB, Mazzeu JF., Free PMC Article | 06/18/2022 |
Novel pathogenic genomic variants leading to autosomal dominant and recessive Robinow syndrome. | Novel pathogenic genomic variants leading to autosomal dominant and recessive Robinow syndrome. Zhang C, Mazzeu JF, Eisfeldt J, Grochowski CM, White J, Akdemir ZC, Jhangiani SN, Muzny DM, Gibbs RA, Lindstrand A, Lupski JR, Sutton VR, Carvalho CMB., Free PMC Article | 03/5/2022 |
ROR1 and ROR2 expression in pancreatic cancer. | ROR1 and ROR2 expression in pancreatic cancer. Liu D, Sharbeen G, Phillips P, Australian Pancreatic Cancer Genome Initiative, Ford CE., Free PMC Article | 02/26/2022 |
Cellular and molecular mechanisms implicated in the dual role of ROR2 in cancer. | Cellular and molecular mechanisms implicated in the dual role of ROR2 in cancer. Castro MV, Lopez-Bergami P. | 02/12/2022 |
Downregulation of ROR2 promotes dental pulp stem cell senescence by inhibiting STK4-FOXO1/SMS1 axis in sphingomyelin biosynthesis. | Downregulation of ROR2 promotes dental pulp stem cell senescence by inhibiting STK4-FOXO1/SMS1 axis in sphingomyelin biosynthesis. Dong XY, Huang YX, Yang Z, Chu XY, Wu J, Wang S, He X, Gao CY, Chen X, Yang K, Zhang DL., Free PMC Article | 02/5/2022 |
Oncogenic E6 and/or E7 proteins drive proliferation and invasion of human papilloma viruspositive head and neck squamous cell cancer through upregulation of Ror2 expression. | Oncogenic E6 and/or E7 proteins drive proliferation and invasion of human papilloma virus‑positive head and neck squamous cell cancer through upregulation of Ror2 expression. Avincsal MO, Kamizaki K, Jimbo N, Shinomiya H, Nibu KI, Nishita M, Minami Y. | 12/4/2021 |
The role of WNT5A and Ror2 in peritoneal membrane injury. | The role of WNT5A and Ror2 in peritoneal membrane injury. Padwal M, Liu L, Margetts PJ., Free PMC Article | 09/11/2021 |
Tomographic Study of the Malformation Complex in Correlation With the Genotype in Patients With Robinow Syndrome: Review Article. | Tomographic Study of the Malformation Complex in Correlation With the Genotype in Patients With Robinow Syndrome: Review Article. Kaissi AA, Kenis V, Shboul M, Grill F, Ganger R, Kircher SG., Free PMC Article | 08/21/2021 |
Clinical and molecular characterization of four patients with Robinow syndrome from different families. | Clinical and molecular characterization of four patients with Robinow syndrome from different families. Rai A, Patil SJ, Srivastava P, Gaurishankar K, Phadke SR. | 08/7/2021 |
Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis. | Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis. Son JH, Lee JU, Chin S, Go ES, Park JS, Shin HK, Chang HS, Park JS, Park CS., Free PMC Article | 07/24/2021 |
ROR2 promotes the epithelial-mesenchymal transition by regulating MAPK/p38 signaling pathway in breast cancer. | ROR2 promotes the epithelial-mesenchymal transition by regulating MAPK/p38 signaling pathway in breast cancer. Xu J, Shi J, Tang W, Jiang P, Guo M, Zhang B, Ma G. | 07/17/2021 |
Knockdown of Ror2 suppresses TNFalphainduced inflammation and apoptosis in vascular endothelial cells. | Knockdown of Ror2 suppresses TNF‑α‑induced inflammation and apoptosis in vascular endothelial cells. Yang X, Zhao S, Yuan H, Shi R, Gu W, Gu Z, Lu X, Zhao H. | 05/8/2021 |
Whole-exome sequencing identified compound heterozygous variants in ROR2 gene in a fetus with Robinow syndrome. | Whole-exome sequencing identified compound heterozygous variants in ROR2 gene in a fetus with Robinow syndrome. Yang K, Zhu J, Tan Y, Sun X, Zhao H, Tang G, Zhang D, Qi H., Free PMC Article | 12/19/2020 |
ROR2 induces cell apoptosis via activating IRE1alpha/JNK/CHOP pathway in high-grade serous ovarian carcinoma in vitro and in vivo. | ROR2 induces cell apoptosis via activating IRE1α/JNK/CHOP pathway in high-grade serous ovarian carcinoma in vitro and in vivo. Li R, Liu T, Shi J, Luan W, Wei X, Yu J, Mao H, Liu P., Free PMC Article | 09/12/2020 |
we found that ROR2 exerts a pivotal role in the adhesion of multiple myeloma cells to the bone marrow microenvironment | The WNT receptor ROR2 drives the interaction of multiple myeloma cells with the microenvironment through AKT activation. Frenquelli M, Caridi N, Antonini E, Storti F, Viganò V, Gaviraghi M, Occhionorelli M, Bianchessi S, Bongiovanni L, Spinelli A, Marcatti M, Belloni D, Ferrero E, Karki S, Brambilla P, Martinelli-Boneschi F, Colla S, Ponzoni M, DePinho RA, Tonon G. | 07/4/2020 |
Cytomegalovirus infection increased ROR2 protein expression in trophoblasts, with no effect on ROR1 and RYK expression, hence regulating trophoblast migration. | Selective modulation of Wnt-binding receptor tyrosine kinase ROR2 expression by human cytomegalovirus regulates trophoblast migration. Huynh KT, van Zuylen WJ, Ford CE, Rawlinson WD. | 10/26/2019 |