| Nucleoporin Nup98 is an essential factor for ipo4 dependent protein import. | Nucleoporin Nup98 is an essential factor for ipo4 dependent protein import.
Guo Y, Tao T, Wu T, Hou J, Lin W. | 08/1/2024 |
| NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation. | NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.
Noura M, Tomita S, Yasuda T, Tsuzuki S, Kiyoi H, Hayakawa F., Free PMC Article | 07/3/2024 |
| Allogeneic hematopoietic stem cell transplantation for adult acute myeloid leukemia patients with nucleoporin 98 (NUP98) gene rearrangements: a real-world study in China. | Allogeneic hematopoietic stem cell transplantation for adult acute myeloid leukemia patients with nucleoporin 98 (NUP98) gene rearrangements: a real-world study in China.
Cao Y, Zhang C, Zhao X, Huang J, Zhang Z, Jiang C, Mo X, Hu X. | 12/5/2023 |
| NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia. | NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia.
Matsukawa T, Yin M, Nigam N, Negi V, Li L, Small D, Zhu YJ, Walker RL, Meltzer PS, Aplan PD., Free PMC Article | 07/7/2023 |
| Molecular interactions of FG nucleoporin repeats at high resolution. | Molecular interactions of FG nucleoporin repeats at high resolution.
Ibáñez de Opakua A, Geraets JA, Frieg B, Dienemann C, Savastano A, Rankovic M, Cima-Omori MS, Schröder GF, Zweckstetter M., Free PMC Article | 11/12/2022 |
| Adult acute myeloid leukemia patients with NUP98 rearrangement have frequent cryptic translocations and unfavorable outcome. | Adult acute myeloid leukemia patients with NUP98 rearrangement have frequent cryptic translocations and unfavorable outcome.
Xie W, Raess PW, Dunlap J, Hoyos CM, Li H, Li P, Swords R, Olson SB, Yang F, Anekpuritanang T, Hu S, Wiszniewska J, Fan G, Press RD, Moore SR. | 08/27/2022 |
| Knockdown of FLT4, Nup98, and Nup205 Cellular Genes Effectively Suppresses the Reproduction of Influenza Virus Strain A/WSN/1933 (H1N1) In vitro. | Knockdown of FLT4, Nup98, and Nup205 Cellular Genes Effectively Suppresses the Reproduction of Influenza Virus Strain A/WSN/1933 (H1N1) In vitro.
Pashkov E, Korchevaya E, Faizuloev E, Rtishchev A, Cherepovich B, Bystritskaya E, Sidorov A, Poddubikov A, Bykov A, Dronina Y, Svitich O, Zverev V. | 07/23/2022 |
| Distinct pathologic feature of myeloid neoplasm with t(v;11p15); NUP98 rearrangement. | Distinct pathologic feature of myeloid neoplasm with t(v;11p15); NUP98 rearrangement.
Lauw MIS, Qi Z, Eversmeyer L, Prakash S, Wen KW, Yu J, Monaghan SA, Aggarwal N, Wang L. | 04/30/2022 |
| Phase separation drives aberrant chromatin looping and cancer development. | Phase separation drives aberrant chromatin looping and cancer development.
Ahn JH, Davis ES, Daugird TA, Zhao S, Quiroga IY, Uryu H, Li J, Storey AJ, Tsai YH, Keeley DP, Mackintosh SG, Edmondson RD, Byrum SD, Cai L, Tackett AJ, Zheng D, Legant WR, Phanstiel DH, Wang GG., Free PMC Article | 01/15/2022 |
| The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype. | The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype.
Vaz M, Fahrenkrog B., Free PMC Article | 01/8/2022 |
| Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL. | Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL.
Goldberg L, Negi V, Chung YJ, Onozawa M, Zhu YJ, Walker RL, Pierce R, Patel DP, Krausz KW, Gonzalez FJ, Goodell MA, Rodriguez BAT, Meltzer PS, Aplan PD., Free PMC Article | 01/8/2022 |
| [Clinical Characteristics and Prognosis of Adult Acute Myeloid Leukemia with NUP98 Gene Rearrangement]. | [Clinical Characteristics and Prognosis of Adult Acute Myeloid Leukemia with NUP98 Gene Rearrangement].
Lu N, Ding Y, Wu YL, Wang LL, Jing Y, Li HH, Li M. | 10/16/2021 |
| The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia. | The clinical and biological characteristics of NUP98-KDM5A in pediatric acute myeloid leukemia.
Noort S, Wander P, Alonzo TA, Smith J, Ries RE, Gerbing RB, Dolman MEM, Locatelli F, Reinhardt D, Baruchel A, Stary J, Molenaar JJ, Stam RW, van den Heuvel-Eibrink MM, Zwaan MC, Meshinchi S., Free PMC Article | 07/10/2021 |
| Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children's Oncology Group. | Acute erythroid leukemia is enriched in NUP98 fusions: a report from the Children's Oncology Group.
Chisholm KM, Heerema-McKenney AE, Choi JK, Smith J, Ries RE, Hirsch BA, Raimondi SC, Alonzo TA, Wang YC, Aplenc R, Sung L, Gamis AS, Meshinchi S, Kahwash SB., Free PMC Article | 06/26/2021 |
| NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia. | NUP-98 Rearrangements Led to the Identification of Candidate Biomarkers for Primary Induction Failure in Pediatric Acute Myeloid Leukemia.
Barresi V, Di Bella V, Andriano N, Privitera AP, Bonaccorso P, La Rosa M, Iachelli V, Spampinato G, Pulvirenti G, Scuderi C, Condorelli DF, Lo Nigro L., Free PMC Article | 06/5/2021 |
| Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex. | Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex.
Kato K, Ikliptikawati DK, Kobayashi A, Kondo H, Lim K, Hazawa M, Wong RW., Free PMC Article | 01/16/2021 |
| SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling. | SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.
Miorin L, Kehrer T, Sanchez-Aparicio MT, Zhang K, Cohen P, Patel RS, Cupic A, Makio T, Mei M, Moreno E, Danziger O, White KM, Rathnasinghe R, Uccellini M, Gao S, Aydillo T, Mena I, Yin X, Martin-Sancho L, Krogan NJ, Chanda SK, Schotsaert M, Wozniak RW, Ren Y, Rosenberg BR, Fontoura BMA, García-Sastre A., Free PMC Article | 12/12/2020 |
| Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. | Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.
Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG., Free PMC Article | 09/5/2020 |
| Collectively, coxsackievirus B3 protease 2A-induced cleavage of NUP98 and subsequent impairment of the cardioprotective NRG1-ERBB4/PSEN1 signaling cascade may contribute to increased myocardial damage in the context of coxsackievirus B3-induced myocarditis. | Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection.
Hanson PJ, Hossain AR, Qiu Y, Zhang HM, Zhao G, Li C, Lin V, Sulaimon S, Vlok M, Fung G, Chen VH, Jan E, McManus BM, Granville DJ, Yang D., Free PMC Article | 07/11/2020 |
| RAE1 and NUP98 participate inBMAL1 shuttling and promote the degradation and activity of BMAL1 and CLOCK. | RAE1 promotes BMAL1 shuttling and regulates degradation and activity of CLOCK: BMAL1 heterodimer.
Zheng X, Zhao X, Zhang Y, Tan H, Qiu B, Ma T, Zeng J, Tao D, Liu Y, Lu Y, Ma Y., Free PMC Article | 04/11/2020 |
| It is the interaction between NUP98/NSD1 and FLT3/ITD that determines the poor outcome of patients with NUP98/NSD1 disease. | NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report.
Ostronoff F, Othus M, Gerbing RB, Loken MR, Raimondi SC, Hirsch BA, Lange BJ, Petersdorf S, Radich J, Appelbaum FR, Gamis AS, Alonzo TA, Meshinchi S., Free PMC Article | 04/10/2020 |
| NUP98-NSD1 is a recurrent genetic abnormality with significant clinical prognostic significance | [Genetic characteristics and clinical outcomes of pediatric acute myeloid leukemia with NUP98-NSD1 fusion gene].
Wang T, Ni JB, Wang XY, Dai Y, Ma XL, Su YC, Gao YY, Chen X, Yuan LL, Liu HX. | 10/5/2019 |
| REVIEW: Nup98 controls gene expression by regulating a DExH/D-box protein | Nucleoplasmic Nup98 controls gene expression by regulating a DExH/D-box protein.
Capitanio JS, Montpetit B, Wozniak RW., Free PMC Article | 09/21/2019 |
| A novel biomarker, NUP98, can predict response to anthracycline based chemotherapy in Triple Negative breast cancer. | NUP98 - a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer.
Mullan PB, Bingham V, Haddock P, Irwin GW, Kay E, McQuaid S, Buckley NE., Free PMC Article | 09/7/2019 |
| study screened 12 NUP98 rearrangements in a cohort of Italian children with acute myeloid leukemia (AML) and found 6 identified a new subgroup of recurrent somatic translocations with a total frequency of 5%. NUP98-rearranged patients had an incidence of relapse higher than that of the general high-risk AML | NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group.
Bisio V, Zampini M, Tregnago C, Manara E, Salsi V, Di Meglio A, Masetti R, Togni M, Di Giacomo D, Minuzzo S, Leszl A, Zappavigna V, Rondelli R, Mecucci C, Pession A, Locatelli F, Basso G, Pigazzi M. | 05/25/2019 |