| Prevalence of the protective OAS1 rs10774671-G allele against severe COVID-19 in Moroccans: implications for a North African Neanderthal connection. | Prevalence of the protective OAS1 rs10774671-G allele against severe COVID-19 in Moroccans: implications for a North African Neanderthal connection.
Yousfi FZE, Haroun AE, Nebhani C, Belayachi J, Askander O, Fahime EE, Fares H, Ennibi K, Abouqal R, Razine R, Bouhouche A., Free PMC Article | 04/26/2024 |
| Possible effect of OAS1 and TMPRSS6 but not DPP4 and ZNF335 polymorphisms on COVID-19 severity in the Czech population. | Possible effect of OAS1 and TMPRSS6 but not DPP4 and ZNF335 polymorphisms on COVID-19 severity in the Czech population.
Hubáček JA, Philipp T, Adámková V, Májek O, Dlouhá D, Dušek L. | 02/7/2024 |
| Features of Distribution of the Allelic Variant of the OAS1 Gene Associated with Severe Form of the Coronavirus Infection in the Russian and Global Populations. | Features of Distribution of the Allelic Variant of the OAS1 Gene Associated with Severe Form of the Coronavirus Infection in the Russian and Global Populations.
Olkova MV, Koshel SM, Petrushenko VS, Alimov AA. | 01/30/2024 |
| Elevation of H3K27me3 level contributes to the radioresistance of nasopharyngeal carcinoma by inhibiting OAS1 expression. | Elevation of H3K27me3 level contributes to the radioresistance of nasopharyngeal carcinoma by inhibiting OAS1 expression.
Zhou Y, Xiao Y, Liu H, Chen Q, Zhu L, Zeng L, Liu X, Pan Y, Zhang J, Fu J, Shao C. | 01/3/2024 |
| The EMT-Related Genes GALNT3 and OAS1 are Associated with Immune Cell Infiltration and Poor Prognosis in Lung Adenocarcinoma. | The EMT-Related Genes GALNT3 and OAS1 are Associated with Immune Cell Infiltration and Poor Prognosis in Lung Adenocarcinoma.
Luo D, Fang M, Shao L, Wang J, Liang Y, Chen M, Gui X, Yan J, Wang W, Yu L, Fan X, Wu Q. | 11/8/2023 |
| The RNA-Binding Proteins OAS1, ZFP36L2, and DHX58 Are Involved in the Regulation of CD44 mRNA Splicing in Colorectal Cancer Cells. | The RNA-Binding Proteins OAS1, ZFP36L2, and DHX58 Are Involved in the Regulation of CD44 mRNA Splicing in Colorectal Cancer Cells.
Novosad VO, Maltseva DV. | 06/29/2023 |
| Genetic Ethnic Differences in Human 2'-5'-Oligoadenylate Synthetase and Disease Associations: A Systematic Review. | Genetic Ethnic Differences in Human 2'-5'-Oligoadenylate Synthetase and Disease Associations: A Systematic Review.
Gokul A, Arumugam T, Ramsuran V., Free PMC Article | 03/3/2023 |
| Genomic and RNA-Seq profiling of patients with HFrEF unraveled OAS1 mutation and aggressive expression. | Genomic and RNA-Seq profiling of patients with HFrEF unraveled OAS1 mutation and aggressive expression.
Li X, Shen Y, Xu X, Guo G, Chen Y, Wei Q, Li H, He K, Liu C. | 02/14/2023 |
| OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1Induced Jak1Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis. | OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis.
Huang YZ, Zheng YX, Zhou Y, Xu F, Cui YZ, Chen XY, Wang ZY, Yan BX, Zheng M, Man XY. | 10/15/2022 |
| Japanese Encephalitis Virus infection increases USP42 to stabilize TRIM21 and OAS1 for neuroinflammatory and anti-viral response in human microglia. | Japanese Encephalitis Virus infection increases USP42 to stabilize TRIM21 and OAS1 for neuroinflammatory and anti-viral response in human microglia.
Mishra R, Kumawat KL, Basu A, Banerjea AC. | 07/23/2022 |
| Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor. | Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor.
Danziger O, Patel RS, DeGrace EJ, Rosen MR, Rosenberg BR., Free PMC Article | 05/14/2022 |
| OAS1 gene, Spike protein variants and persistent COVID-19-related anosmia: may the olfactory disfunction be a harbinger of future neurodegenerative disease? | OAS1 gene, Spike protein variants and persistent COVID-19-related anosmia: may the olfactory disfunction be a harbinger of future neurodegenerative disease?
Di Stadio A, Bernitsas E, Ralli M, Severini C, Brenner MJ, Angelini C. | 04/30/2022 |
| Genetic predisposition in the 2'-5'A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity. | Genetic predisposition in the 2'-5'A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity.
Pedersen K, Haupt-Jorgensen M, Krogvold L, Kaur S, Gerling IC, Pociot F, Dahl-Jørgensen K, Buschard K., Free PMC Article | 03/19/2022 |
| OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis. | OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis.
Boehmer DFR, Formisano S, de Oliveira Mann CC, Mueller SA, Kluge M, Metzger P, Rohlfs M, Hörth C, Kocheise L, Lichtenthaler SF, Hopfner KP, Endres S, Rothenfusser S, Friedel CC, Duewell P, Schnurr M, Koenig LM. | 03/12/2022 |
| Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19. | Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19.
Huffman JE, Butler-Laporte G, Khan A, Pairo-Castineira E, Drivas TG, Peloso GM, Nakanishi T, COVID-19 Host Genetics Initiative, Ganna A, Verma A, Baillie JK, Kiryluk K, Richards JB, Zeberg H., Free PMC Article | 02/26/2022 |
| Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs. | Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs.
Schwartz SL, Dey D, Tanquary J, Bair CR, Lowen AC, Conn GL., Free PMC Article | 02/26/2022 |
| Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency. | Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency.
Magg T, Okano T, Koenig LM, Boehmer DFR, Schwartz SL, Inoue K, Heimall J, Licciardi F, Ley-Zaporozhan J, Ferdman RM, Caballero-Oteyza A, Park EN, Calderon BM, Dey D, Kanegane H, Cho K, Montin D, Reiter K, Griese M, Albert MH, Rohlfs M, Gray P, Walz C, Conn GL, Sullivan KE, Klein C, Morio T, Hauck F., Free PMC Article | 02/26/2022 |
| A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene. | A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.
Magusali N, Graham AC, Piers TM, Panichnantakul P, Yaman U, Shoai M, Reynolds RH, Botia JA, Brookes KJ, Guetta-Baranes T, Bellou E, Bayram S, Sokolova D, Ryten M, Sala Frigerio C, Escott-Price V, Morgan K, Pocock JM, Hardy J, Salih DA., Free PMC Article | 01/22/2022 |
| A prenylated dsRNA sensor protects against severe COVID-19. | A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G, ISARIC4C Investigators, Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ., Free PMC Article | 11/13/2021 |
| Length dependent activation of OAS proteins by dsRNA. | Length dependent activation of OAS proteins by dsRNA.
Wang Y, Holleufer A, Gad HH, Hartmann R. | 07/31/2021 |
| A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity. | A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity.
Zhou S, Butler-Laporte G, Nakanishi T, Morrison DR, Afilalo J, Afilalo M, Laurent L, Pietzner M, Kerrison N, Zhao K, Brunet-Ratnasingham E, Henry D, Kimchi N, Afrasiabi Z, Rezk N, Bouab M, Petitjean L, Guzman C, Xue X, Tselios C, Vulesevic B, Adeleye O, Abdullah T, Almamlouk N, Chen Y, Chassé M, Durand M, Paterson C, Normark J, Frithiof R, Lipcsey M, Hultström M, Greenwood CMT, Zeberg H, Langenberg C, Thysell E, Pollak M, Mooser V, Forgetta V, Kaufmann DE, Richards JB. | 05/1/2021 |
| Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death. | Suppressing PARylation by 2',5'-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death.
Kondratova AA, Cheon H, Dong B, Holvey-Bates EG, Hasipek M, Taran I, Gaughan C, Jha BK, Silverman RH, Stark GR., Free PMC Article | 04/13/2021 |
| Characteristics of Human OAS1 Isoform Proteins. | Characteristics of Human OAS1 Isoform Proteins.
Di H, Elbahesh H, Brinton MA., Free PMC Article | 02/20/2021 |
| Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs. | Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs.
Schwartz SL, Park EN, Vachon VK, Danzy S, Lowen AC, Conn GL., Free PMC Article | 09/19/2020 |
| Study of datasets analyzing the gene expression profiles and DNA methylation data of gestational Diabetes Mellitus (GDM) and confirmed through real time PCR in placenta tissue of three GDM samples and three normal samples identified Oas1, Ppie, Polr2g as possible pathogenic target genes of GDM by combining protein-protein interaction analysis. | Comprehensive Analysis of Gene Expression Profiles and DNA Methylome reveals Oas1, Ppie, Polr2g as Pathogenic Target Genes of Gestational Diabetes Mellitus.
Zhang Y, Zhang T, Chen Y., Free PMC Article | 11/23/2019 |