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    TNFRSF11B TNF receptor superfamily member 11b [ Homo sapiens (human) ]

    Gene ID: 4982, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Osteoprotegerin mediates adipogenesis in obesity.

    Osteoprotegerin mediates adipogenesis in obesity.
    Lyu Z, Chan YT, Lu Y, Fung Lam T, Wu X, Wu J, Xu L, Yang W, Zhang C, Lidan Zhong L, Wang N., Free PMC Article

    07/22/2024
    Osteoprotegerin and receptor activator of the nuclear factor kappa B ligand (RANKL) in healthy pubertal girls - relationships with physical growth and classical bone turnover markers.

    Osteoprotegerin and receptor activator of the nuclear factor kappa B ligand (RANKL) in healthy pubertal girls - relationships with physical growth and classical bone turnover markers.
    Kulik-Rechberger B, Kozłowska M.

    04/12/2024
    Osteopontin, osteoprotegerin and musculoskeletal ultrasound findings in first-degree relatives of rheumatoid arthritis: potential markers of preclinical disease.

    Osteopontin, osteoprotegerin and musculoskeletal ultrasound findings in first-degree relatives of rheumatoid arthritis: potential markers of preclinical disease.
    Soliman E, Ohrndorf S, Zehairy M, Matrawy K, Alhadidy A, Abdelati A., Free PMC Article

    03/7/2024
    Osteoprotegerin is associated with subclinical left ventricular systolic dysfunction in non-dipper hypertensive patients: a 2D speckle tracking echocardiographic study.

    Osteoprotegerin is associated with subclinical left ventricular systolic dysfunction in non-dipper hypertensive patients: a 2D speckle tracking echocardiographic study.
    Alizade E, Kahyaoglu M, Balaban I, Izci S, Guler A.

    03/4/2024
    Circulating osteoprotegerin levels and cardiovascular outcomes in patients with pre-dialysis chronic kidney disease: results from the KNOW-CKD study.

    Circulating osteoprotegerin levels and cardiovascular outcomes in patients with pre-dialysis chronic kidney disease: results from the KNOW-CKD study.
    Suh SH, Oh TR, Choi HS, Kim CS, Bae EH, Ma SK, Oh KH, Lee KB, Jeong JC, Jung JY, Kim SW, Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) Investigators., Free PMC Article

    03/4/2024
    Correlates of Circulating Osteoprotegerin in Women with a Pathogenic or Likely Pathogenic Variant in the BRCA1 Gene.

    Correlates of Circulating Osteoprotegerin in Women with a Pathogenic or Likely Pathogenic Variant in the BRCA1 Gene.
    Park SS, Zaman T, Kim SJ, Brooks JD, Wong AKO, Lubiński J, Narod SA, Salmena L, Kotsopoulos J.

    02/13/2024
    Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage.

    Downregulation of osteoprotegerin in colorectal cancer cells promotes liver metastasis via activating tumor-associated macrophage.
    Hirata W, Itatani Y, Masui H, Kawada K, Mizuno R, Yamamoto T, Okamoto T, Ogawa R, Inamoto S, Maekawa H, Okamura R, Kiyasu Y, Hanada K, Okamoto M, Nishikawa Y, Sugimoto N, Tamura T, Hatano E, Sakai Y, Obama K., Free PMC Article

    12/20/2023
    Association of rs2073618 polymorphism and osteoprotegerin levels with hypertension and cardiovascular risks in patients with type 2 diabetes mellitus.

    Association of rs2073618 polymorphism and osteoprotegerin levels with hypertension and cardiovascular risks in patients with type 2 diabetes mellitus.
    Sailaja AN, Nanda N, Suryanarayana BS, Pal GK., Free PMC Article

    10/25/2023
    Identification and Association of Polymorphism rs2073618 of the <em>Osteoprotegerin </em>Gene in Type 2 Diabetics with and without Retinopathy.

    Identification and Association of Polymorphism rs2073618 of the <em>Osteoprotegerin </em>Gene in Type 2 Diabetics with and without Retinopathy.
    Tariq E, Waheed P, Majeed A, Rashid A.

    09/28/2023
    Genetically predicted osteoprotegerin levels and the risk of cardiovascular diseases: A Mendelian randomization study.

    Genetically predicted osteoprotegerin levels and the risk of cardiovascular diseases: A Mendelian randomization study.
    Zhu Y, Wang Y, Liu X, Wang Y, Cui Z, Liu F, Hu J.

    09/13/2023
    Bone mineral density in egyptian children with juvenile idiopathic arthritis: possible correlation to serum RANKL / osteoprotegerin (OPG) ratio and OPG gene polymorphisms.

    Bone mineral density in egyptian children with juvenile idiopathic arthritis: possible correlation to serum RANKL / osteoprotegerin (OPG) ratio and OPG gene polymorphisms.
    Eid R, Abdelsalam M, Fathy AA, Abolenein HM, Elmarghany EB, El-Hanafy AA, Hamdy N, Abd-Elmagid DS, Niazy NA, Abd-El Ghaffar DM., Free PMC Article

    06/23/2023
    MiR-217 regulates autophagy through OPG/RANKL/RANK in giant cell tumors.

    MiR-217 regulates autophagy through OPG/RANKL/RANK in giant cell tumors.
    Meng C, Jiang B, Liu W, Wang L, Zhao Z, Bai R, Zhao Y., Free PMC Article

    05/17/2023
    Association of osteoporosis risk and polymorphisms of osteoprotegerin gene T950C in postmenopausal Chinese women: A PRISMA-compliant meta-analysis.

    Association of osteoporosis risk and polymorphisms of osteoprotegerin gene T950C in postmenopausal Chinese women: A PRISMA-compliant meta-analysis.
    Xia Y, Chen H., Free PMC Article

    04/12/2023
    Cellular voids in the pathogenesis of otosclerosis.

    Cellular voids in the pathogenesis of otosclerosis.
    Hansen LJ, Bloch SL, Sørensen MS.

    04/4/2023
    Osteoprotegerin, Chitinase 3-like Protein 1, and Cardiotrophin-1 as Potential Biomarkers of Obstructive Sleep Apnea in Adults-A Case-Control Study.

    Osteoprotegerin, Chitinase 3-like Protein 1, and Cardiotrophin-1 as Potential Biomarkers of Obstructive Sleep Apnea in Adults-A Case-Control Study.
    Fiedorczuk P, Olszewska E, Rogalska J, Brzóska MM., Free PMC Article

    02/16/2023
    The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro.

    The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro.
    Zhu J, Ma Y, Wang J, Wang Y, Ali W, Zou H, Zhao H, Tong X, Song R, Liu Z., Free PMC Article

    01/28/2023
    The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies.

    The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies.
    Zhang Y, Liang J, Liu P, Wang Q, Liu L, Zhao H., Free PMC Article

    01/14/2023
    Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization.

    Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization.
    Rodríguez Ruiz A, van Hoolwerff M, Sprangers S, Suchiman E, Schoenmaker T, Dibbets-Schneider P, Bloem JL, Nelissen RGHH, Freund C, Mummery C, Everts V, de Vries TJ, Ramos YFM, Meulenbelt I., Free PMC Article

    01/11/2023
    Association between Osteoprotegerin rs2073618 polymorphism and peri-implantitis susceptibility: a meta-analysis.

    Association between Osteoprotegerin rs2073618 polymorphism and peri-implantitis susceptibility: a meta-analysis.
    Xu M, Zhang C, Han Y, Yue Z, Shu C, Hou J., Free PMC Article

    01/11/2023
    Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling.

    Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling.
    Al-Nasrallah HK, Al-Ansari MM, Aboussekhra A., Free PMC Article

    11/26/2022
    Risk association of RANKL and OPG gene polymorphism with breast cancer to bone metastasis in Pashtun population of Khyber Pakhtunkhwa, Pakistan.

    Risk association of RANKL and OPG gene polymorphism with breast cancer to bone metastasis in Pashtun population of Khyber Pakhtunkhwa, Pakistan.
    Hayat F, Khan NU, Khan AU, Ahmad I, Alamri AM, Iftikhar B., Free PMC Article

    11/19/2022
    The role of IL-6 and osteoprotegerin in bone metabolism in patients with Graves' disease.

    The role of IL-6 and osteoprotegerin in bone metabolism in patients with Graves' disease.
    Omma T, Yücel Ç, Sertoğlu E, Fırat SN, Çulha C, Özgürtaş T., Free PMC Article

    10/1/2022
    Biochemical characterization of a disease-causing human osteoprotegerin variant.

    Biochemical characterization of a disease-causing human osteoprotegerin variant.
    Luo Y, Li M, Xu D., Free PMC Article

    10/1/2022
    Decreased level of soluble receptor activator of nuclear factor-kappabeta ligand (sRANKL) in overweight and obese children.

    Decreased level of soluble receptor activator of nuclear factor-κβ ligand (sRANKL) in overweight and obese children.
    Erazmus M, Rumińska M, Witkowska-Sędek E, Kucharska AM, Stelmaszczyk-Emmel A, Majcher A, Pyrżak B., Free PMC Article

    09/17/2022
    The Effect of Osteoprotectin (OPG)/Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL)/Receptor Activator of Nuclear Factor-kappaB (RANK) Gene Methylation on Aortic Valve Calcified.

    The Effect of Osteoprotectin (OPG)/Receptor Activator of Nuclear Factor-κB Ligand (RANKL)/Receptor Activator of Nuclear Factor-κB (RANK) Gene Methylation on Aortic Valve Calcified.
    Luo W, Song Y, Wang J, Yang X, Li Z, Cong H., Free PMC Article

    09/17/2022
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