| Intraflagellar transport protein 88 interacts with polycystin 2 to regulate mechanosensitive hedgehog signaling in mandibular condylar chondrocytes. | Intraflagellar transport protein 88 interacts with polycystin 2 to regulate mechanosensitive hedgehog signaling in mandibular condylar chondrocytes.
Wang Z, Sa G, Zheng L, Wei Z, Zhang Z, Hu Y, Yang X. | 10/15/2022 |
| [Effect of polycystin2 on differentiation and maturation of osteoblasts promoted by low-frequency pulsed electromagnetic fields]. | [Effect of polycystin2 on differentiation and maturation of osteoblasts promoted by low-frequency pulsed electromagnetic fields].
He Y, Yang M, Chen Z, Wei P, Qin K, Xie G, Chen K. | 04/9/2022 |
| High-salt intake increased TRPP2 expression in vascular smooth muscle cells, which in turn potentiated blood vessel response to contractors; this may participate in the development of hypertension. | Increased TRPP2 expression in vascular smooth muscle cells from high-salt intake hypertensive rats: The crucial role in vascular dysfunction.
Zhao R, Zhou M, Li J, Wang X, Su K, Hu J, Ye Y, Zhu J, Zhang G, Wang K, Du J, Wang L, Shen B. | 10/10/2015 |
| TRPV4, TRPC1, and TRPP2 contribute to the ion permeation pore of the channels | TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel.
Du J, Ma X, Shen B, Huang Y, Birnbaumer L, Yao X., Free PMC Article | 09/9/2015 |
| Both polycystins were detected on the spindle and mid-body of mitotic cells, while fibrocystin was on centrosome throughout cell cycle. | Expression of polycystins and fibrocystin on primary cilia of lung cells.
Hu Q, Wu Y, Tang J, Zheng W, Wang Q, Nahirney D, Duszyk M, Wang S, Tu JC, Chen XZ. | 07/25/2015 |
| The reactivity of Muller glial cells in retinas of rats that express defective polycystin-2, is reported. | Müller cell reactivity in response to photoreceptor degeneration in rats with defective polycystin-2.
Vogler S, Pannicke T, Hollborn M, Grosche A, Busch S, Hoffmann S, Wiedemann P, Reichenbach A, Hammes HP, Bringmann A., Free PMC Article | 01/31/2015 |
| These novel findings demonstrate intracellular Ca(2+)-dependent PC2 trafficking in human and rat kidney cells, which may provide new insight into cyst formations in ADPKD. | Intracellular calcium release modulates polycystin-2 trafficking.
Miyakawa A, Ibarra C, Malmersjö S, Aperia A, Wiklund P, Uhlén P., Free PMC Article | 07/13/2013 |
| Polycystin-2 is increased after renal ischaemia. Increase not restricted to actively proliferating cells. Increase may relate to process of cellular repair or differentiation following injury. | Polycystin-2 expression is increased following experimental ischaemic renal injury.
Zhao Y, Haylor JL, Ong AC, Zhao Y, Haylor JL, Ong AC. | 08/14/2012 |
| Polycystin-2 is increased after renal ischaemia. Increase not restricted to actively proliferating cells. Increase may relate to process of cellular repair or differentiation following injury | Polycystin-2 expression is increased following experimental ischaemic renal injury.
Zhao Y, Haylor JL, Ong AC, Zhao Y, Haylor JL, Ong AC. | 08/14/2012 |
| Cholangiocyte proliferation was associated with decreased PC-1(polycystin 1) and PC-2 (polycystin 2) expression | Polycystins play a key role in the modulation of cholangiocyte proliferation.
Torrice A, Cardinale V, Gatto M, Semeraro R, Napoli C, Onori P, Alpini G, Gaudio E, Alvaro D. | 08/16/2010 |
| analysis of vasoregression linked to neuronal damage in the rat with defect of polycystin-2 | Vasoregression linked to neuronal damage in the rat with defect of polycystin-2.
Feng Y, Wang Y, Stock O, Pfister F, Tanimoto N, Seeliger MW, Hillebrands JL, Hoffmann S, Wolburg H, Gretz N, Hammes HP., Free PMC Article | 03/15/2010 |
| polycystin-1, polycystin-2, and fibrocystin are shed in membrane particles in the urine, and these particles interact with primary cilia | Characterization of PKD protein-positive exosome-like vesicles.
Hogan MC, Manganelli L, Woollard JR, Masyuk AI, Masyuk TV, Tammachote R, Huang BQ, Leontovich AA, Beito TG, Madden BJ, Charlesworth MC, Torres VE, LaRusso NF, Harris PC, Ward CJ., Free PMC Article | 01/21/2010 |
| Over-expression of wild-type PKD2 in renal cell lines failed to inactivate Cdk2 and consequently had no effect on cell proliferation. | Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.
Felekkis KN, Koupepidou P, Kastanos E, Witzgall R, Bai CX, Li L, Tsiokas L, Gretz N, Deltas C., Free PMC Article | 01/21/2010 |