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    OVOL1 ovo like transcriptional repressor 1 [ Homo sapiens (human) ]

    Gene ID: 5017, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-beta type I receptor.

    OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor.
    Fan C, Wang Q, van der Zon G, Ren J, Agaser C, Slieker RC, Iyengar PV, Mei H, Ten Dijke P., Free PMC Article

    05/7/2022
    Association of HLA-DPB1, NLRP10, OVOL1, and ABCC11 with the axillary microbiome in a Japanese population.

    Association of HLA-DPB1, NLRP10, OVOL1, and ABCC11 with the axillary microbiome in a Japanese population.
    Kutsuwada Y, Yokota K, Yoshida K, Tsuda H, Watanabe K, Matsumoto A, Iwamoto S.

    03/19/2022
    OVOL1 Regulates Psoriasis-Like Skin Inflammation and Epidermal Hyperplasia.

    OVOL1 Regulates Psoriasis-Like Skin Inflammation and Epidermal Hyperplasia.
    Sun P, Vu R, Dragan M, Haensel D, Gutierrez G, Nguyen Q, Greenberg E, Chen Z, Wu J, Atwood S, Pearlman E, Shi Y, Han W, Kessenbrock K, Dai X., Free PMC Article

    11/22/2021
    The transcription factor OVOL1 as a potential regulator of an alternative epithelial cell fate.

    OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates.
    Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K., Free PMC Article

    03/7/2020
    OVOL1 is an integral part of the aryl hydrocarbon receptor-mediated mechanism of Filaggrin expression in human keratinocytes.

    Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis.
    Tsuji G, Hashimoto-Hachiya A, Kiyomatsu-Oda M, Takemura M, Ohno F, Ito T, Morino-Koga S, Mitoma C, Nakahara T, Uchi H, Furue M., Free PMC Article

    05/19/2018
    Taken together, this study suggests that the OVOL1-OVOL2 axis is a key modulator of c-Myc expression in the shift from in situ epidermal malignancy (Bowen's disease) to invasive squamous cell carcinoma.

    Potential role of the OVOL1-OVOL2 axis and c-Myc in the progression of cutaneous squamous cell carcinoma.
    Ito T, Tsuji G, Ohno F, Nakahara T, Uchi H, Furue M.

    04/14/2018
    that the OVOL1-OVOL2 axis may actively contribute to cell differentiation and proliferation in the hair bulb

    Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma.
    Ito T, Tsuji G, Ohno F, Uchi H, Nakahara T, Hashimoto-Hachiya A, Yoshida Y, Yamamoto O, Oda Y, Furue M.

    09/10/2016
    OVOL1 is a regulator of trophoblast progenitor cell fate during human trophoblast development.

    OVO-like 1 regulates progenitor cell fate in human trophoblast development.
    Renaud SJ, Chakraborty D, Mason CW, Rumi MA, Vivian JL, Soares MJ., Free PMC Article

    02/27/2016
    KIF3A and OVOL1 are involved in the development of Atopic dermatitis in the Chinese pediatric population.

    Correlation of KIF3A and OVOL1, but not ACTL9, with atopic dermatitis in Chinese pediatric patients.
    Kang Z, Li Q, Fu P, Yan S, Guan M, Xu J, Xu F.

    12/12/2015
    OVOL1 may play an important role in human skin morphogenesis and tumorigenesis.

    Preferential expression of OVOL1 in inner root sheath of hair, sebaceous gland, eccrine duct and their neoplasms in human skin.
    Mitoma C, Nakahara T, Uchi H, Ito T, Inatomi Y, Ide T, Jinnai S, Jinnai N, Iwasaki N, Sakamoto K, Kimura N, Maeda A, Kuma Y, Maehara E, Tsutsumi M, Kido-Nakahara M, Hirota T, Tamari M, Furue M.

    01/24/2015
    Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients

    Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients.
    Lepre T, Cascella R, Ragazzo M, Galli E, Novelli G, Giardina E.

    11/16/2013
    Molecular phylogeny of OVOL1, OVOL2 and OVOL3 genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions in humans and other species

    Molecular phylogeny of OVOL genes illustrates a conserved C2H2 zinc finger domain coupled by hypervariable unstructured regions.
    Kumar A, Bhandari A, Sinha R, Sardar P, Sushma M, Goyal P, Goswami C, Grapputo A., Free PMC Article

    12/22/2012
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
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