| Porocarcinomas with PAK1/2/3 fusions: a series of 12 cases. | Porocarcinomas with PAK1/2/3 fusions: a series of 12 cases.
Kervarrec T, Westphal D, Pissaloux D, Legrand M, Tirode F, Neuhart A, Drouot F, Becker JC, Macagno N, Seris A, Jouary T, Beltzung F, Jullie ML, Harms PW, Cribier B, Mourah S, Jouenne F, Fromont G, Louveau B, Mancini M, Kazakov DV, de la Fouchardière A, Battistella M. | 09/6/2024 |
| ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription. | ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription.
Wu D, Zuo Z, Sun X, Li X, Yin F, Yin W. | 06/5/2024 |
| Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2. | Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2.
Yang H, Li Z, Zhu S, Wang W, Zhang J, Zhao D, Zhang M, Zhu W, Xu W, Xu C., Free PMC Article | 02/16/2024 |
| A novel pipeline for prioritizing cancer type-specific therapeutic vulnerabilities using DepMap identifies PAK2 as a target in head and neck squamous cell carcinomas. | A novel pipeline for prioritizing cancer type-specific therapeutic vulnerabilities using DepMap identifies PAK2 as a target in head and neck squamous cell carcinomas.
Sannigrahi MK, Cao AC, Rajagopalan P, Sun L, Brody RM, Raghav L, Gimotty PA, Basu D., Free PMC Article | 02/12/2024 |
| Recurrent PAK2 rearrangements in poroma with folliculo-sebaceous differentiation. | Recurrent PAK2 rearrangements in poroma with folliculo-sebaceous differentiation.
Kervarrec T, Pissaloux D, Paindavoine S, Tirode F, Osio A, Mourah S, Jouenne F, Sohier P, Calonje E, Pekar A, Luna EVE, Goto K, Delalande F, Frouin E, Macagno N, Drouot F, Faisan M, Cribier B, Battistella M, de la Fouchardière A. | 07/12/2023 |
| Loss-of-Function of p21-Activated Kinase 2 Links BMP Signaling to Neural Tube Patterning Defects. | Loss-of-Function of p21-Activated Kinase 2 Links BMP Signaling to Neural Tube Patterning Defects.
Wang Y, Zhang K, Guo J, Yang S, Shi X, Pan J, Sun Z, Zou J, Li Y, Li Y, Fan T, Song W, Cheng F, Zeng C, Li J, Zhang T, Sun ZS., Free PMC Article | 02/10/2023 |
| Circular RNA 0001789 sponges miR-140-3p and regulates PAK2 to promote the progression of gastric cancer. | Circular RNA 0001789 sponges miR-140-3p and regulates PAK2 to promote the progression of gastric cancer.
You J, Chen Y, Chen D, Li Y, Wang T, Zhu J, Hong Q, Li Q., Free PMC Article | 02/9/2023 |
| Quantitative Phosphoproteomics Analysis Uncovers PAK2- and CDK1-Mediated Malignant Signaling Pathways in Clear Cell Renal Cell Carcinoma. | Quantitative Phosphoproteomics Analysis Uncovers PAK2- and CDK1-Mediated Malignant Signaling Pathways in Clear Cell Renal Cell Carcinoma.
Senturk A, Sahin AT, Armutlu A, Kiremit MC, Acar O, Erdem S, Bagbudar S, Esen T, Ozlu N., Free PMC Article | 12/3/2022 |
| p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma. | p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.
Xie S, Wan X, Chen S, Hu Y, Liu X. | 10/8/2022 |
| LncRNA FAF attenuates hypoxia/ischaemia-induced pyroptosis via the miR-185-5p/PAK2 axis in cardiomyocytes. | LncRNA FAF attenuates hypoxia/ischaemia-induced pyroptosis via the miR-185-5p/PAK2 axis in cardiomyocytes.
Gu J, Shi JZ, Wang YX, Liu L, Wang SB, Sun JT, Shan TK, Wang H, Wang QM, Wang LS., Free PMC Article | 05/21/2022 |
| miR-511-5p Suppresses Cell Migration, Invasion and Epithelial-Mesenchymal Transition Through Targeting PAK2 in Gastric Cancer. | miR-511-5p Suppresses Cell Migration, Invasion and Epithelial-Mesenchymal Transition Through Targeting PAK2 in Gastric Cancer.
Yong W, Zhang K, Deng Y, Tang W, Tao R. | 05/14/2022 |
| Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling. | Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling.
Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR., Free PMC Article | 05/7/2022 |
| Cancer-released exosomal circular RNA circ_0008717 promotes cell tumorigenicity through microRNA-1287-5p/P21-activated kinase 2 (PAK2) axis in non-small cell lung cancer. | Cancer-released exosomal circular RNA circ_0008717 promotes cell tumorigenicity through microRNA-1287-5p/P21-activated kinase 2 (PAK2) axis in non-small cell lung cancer.
Wang H, Tang Z, Duan J, Zhou C, Xu K, Mu H., Free PMC Article | 05/7/2022 |
| Dominant monoallelic variant in the PAK2 gene causes Knobloch syndrome type 2. | Dominant monoallelic variant in the PAK2 gene causes Knobloch syndrome type 2.
Antonarakis SE, Holoubek A, Rapti M, Rademaker J, Meylan J, Iwaszkiewicz J, Zoete V, Wilson C, Taylor J, Ansar M, Borel C, Menzel O, Kuželová K, Santoni FA. | 04/16/2022 |
| PAK1 and PAK2 in cell metabolism regulation. | PAK1 and PAK2 in cell metabolism regulation.
Kořánová T, Dvořáček L, Grebeňová D, Röselová P, Obr A, Kuželová K. | 04/2/2022 |
| hsa_circ_0013401 Accelerates the Growth and Metastasis and Prevents Apoptosis and Autophagy of Neuroblastoma Cells by Sponging miR-195 to Release PAK2. | hsa_circ_0013401 Accelerates the Growth and Metastasis and Prevents Apoptosis and Autophagy of Neuroblastoma Cells by Sponging miR-195 to Release PAK2.
Zhu S, Tang X, Gao X, Zhang J, Cui Y, Li D, Jia W., Free PMC Article | 02/26/2022 |
| miR-107 regulates the effect of MCM7 on the proliferation and apoptosis of colorectal cancer via the PAK2 pathway. | miR-107 regulates the effect of MCM7 on the proliferation and apoptosis of colorectal cancer via the PAK2 pathway.
Zhao M, Wang Y, Jiang C, Wang Q, Mi J, Zhang Y, Zuo L, Geng Z, Song X, Ge S, Li J, Wen H, Wang J, Wang Z, Su F. | 11/22/2021 |
| LINC00858 promotes colorectal cancer by sponging miR-4766-5p to regulate PAK2. | LINC00858 promotes colorectal cancer by sponging miR-4766-5p to regulate PAK2.
Zhan W, Liao X, Chen Z, Li L, Tian T, Yu L, Li R. | 06/12/2021 |
| Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Hepatic Stellate Cell Activation and Liver Fibrosis by Upregulating MicroRNA-455-3p through Suppression of p21-Activated Kinase-2. | Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Hepatic Stellate Cell Activation and Liver Fibrosis by Upregulating MicroRNA-455-3p through Suppression of p21-Activated Kinase-2.
Zhou Q, Gu T, Zhang Y, Li H, Zhuansun X, Xu S, Kuang Y., Free PMC Article | 05/29/2021 |
| CDK12 and PAK2 as novel therapeutic targets for human gastric cancer. | CDK12 and PAK2 as novel therapeutic targets for human gastric cancer.
Liu H, Shin SH, Chen H, Liu T, Li Z, Hu Y, Liu F, Zhang C, Kim DJ, Liu K, Dong Z., Free PMC Article | 05/22/2021 |
| Prognostic significance of PAK family kinases in acute myeloid leukemia. | Prognostic significance of PAK family kinases in acute myeloid leukemia.
Quan L, Cheng Z, Dai Y, Jiao Y, Shi J, Fu L. | 05/15/2021 |
| ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly. | ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly.
Tixeira R, Phan TK, Caruso S, Shi B, Atkin-Smith GK, Nedeva C, Chow JDY, Puthalakath H, Hulett MD, Herold MJ, Poon IKH., Free PMC Article | 04/3/2021 |
| Pak2 inhibition promotes resveratrol-mediated glioblastoma A172 cell apoptosis via modulating the AMPK-YAP signaling pathway. | Pak2 inhibition promotes resveratrol-mediated glioblastoma A172 cell apoptosis via modulating the AMPK-YAP signaling pathway.
Xing J, Wang Z, Xu H, Liu C, Wei Z, Zhao L, Ren L. | 03/6/2021 |
| CCHE1 accelerated the initiation of oral squamous cell carcinoma through enhancing PAK2 expression by sponging miR-922. | CCHE1 accelerated the initiation of oral squamous cell carcinoma through enhancing PAK2 expression by sponging miR-922.
Wang Y, Tong J, Lin H, Ma L, Xu Y. | 11/21/2020 |
| PAK1, PAK1Delta15, and PAK2: similarities, differences and mutual interactions. | PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions.
Grebeňová D, Holoubek A, Röselová P, Obr A, Brodská B, Kuželová K., Free PMC Article | 11/21/2020 |