| Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography. | Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography.
Rudran T, Antoniak S, Flick MJ, Ginsberg MH, Wolberg AS, Bergmeier W, Lee RH., Free PMC Article | 09/12/2023 |
| Glycoprotein VI interplay with fibrin(ogen) in thrombosis. | Glycoprotein VI interplay with fibrin(ogen) in thrombosis.
Mangin PH, Gardiner EE, Ariëns RAS, Jandrot-Perrus M. | 06/23/2023 |
| Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. | Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets.
Zhang P, Solari FA, Heemskerk JWM, Kuijpers MJE, Sickmann A, Walter U, Jurk K., Free PMC Article | 05/19/2023 |
| Platelet Activation via Glycoprotein VI Initiates Thrombin Generation: A Potential Role for Platelet-Derived Factor IX? | Platelet Activation via Glycoprotein VI Initiates Thrombin Generation: A Potential Role for Platelet-Derived Factor IX?
Li L, Roest M, Meijers JCM, de Laat B, Urbanus RT, de Groot PG, Huskens D. | 09/3/2022 |
| GPVI expression is linked to platelet size, age, and reactivity. | GPVI expression is linked to platelet size, age, and reactivity.
Veninga A, Handtke S, Aurich K, Tullemans BME, Brouns SLN, Schwarz SL, Heubel-Moenen FCJI, Greinacher A, Heemskerk JWM, van der Meijden PEJ, Thiele T., Free PMC Article | 07/30/2022 |
| Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation. | Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. | 03/12/2022 |
| Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results. | Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results.
Induruwa I, McKinney H, Kempster C, Thomas P, Batista J, Malcor JD, Bonna A, McGee J, Bumanlag-Amis E, Rehnstrom K, Ashford S, Soejima K, Ouwehand W, Farndale R, Downes K, Warburton E, Moroi M, Jung S., Free PMC Article | 02/26/2022 |
| Differential Role of Glycoprotein VI in Mouse and Human Thrombus Progression and Stability. | Differential Role of Glycoprotein VI in Mouse and Human Thrombus Progression and Stability.
Janus-Bell E, Ahmed MU, Receveur N, Mouriaux C, Nieswandt B, Gardiner EE, Gachet C, Jandrot-Perrus M, Mangin PH. | 01/8/2022 |
| Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer. | Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer.
Slater A, Di Y, Clark JC, Jooss NJ, Martin EM, Alenazy F, Thomas MR, Ariëns RAS, Herr AB, Poulter NS, Emsley J, Watson SP. | 12/4/2021 |
| Acquired platelet GPVI receptor dysfunction in critically ill patients with sepsis. | Acquired platelet GPVI receptor dysfunction in critically ill patients with sepsis.
Weiss LJ, Manukjan G, Pflug A, Winter N, Weigel M, Nagler N, Kredel M, Lâm TT, Nieswandt B, Weismann D, Schulze H. | 12/4/2021 |
| Long-term platelet priming after glycoprotein VI stimulation in comparison to Protease-Activating Receptor (PAR) stimulation. | Long-term platelet priming after glycoprotein VI stimulation in comparison to Protease-Activating Receptor (PAR) stimulation.
Zou J, Wu J, Roest M, Heemskerk JWM., Free PMC Article | 09/4/2021 |
| Dimers of the platelet collagen receptor glycoprotein VI bind specifically to fibrin fibers during clot formation, but not to intact fibrinogen. | Dimers of the platelet collagen receptor glycoprotein VI bind specifically to fibrin fibers during clot formation, but not to intact fibrinogen.
Moroi M, Induruwa I, Farndale RW, Jung SM. | 08/14/2021 |
| A fibrinolytic snake venom metalloproteinase, mutalysin-II, with antiplatelet activity and targeting capability toward glycoprotein GPIbalpha and glycoprotein GPVI. | A fibrinolytic snake venom metalloproteinase, mutalysin-II, with antiplatelet activity and targeting capability toward glycoprotein GPIbα and glycoprotein GPVI.
Sanchez EF, Alvarenga VG, Oliveira LS, Oliveira DL, Estevao-Costa MI, Flores-Ortiz R, Eble JA. | 07/17/2021 |
| Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood. | Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood.
Zhang D, Ebrahim M, Adler K, Blanchet X, Jamasbi J, Megens RTA, Uhland K, Ungerer M, Münch G, Deckmyn H, Weber C, Elia N, Lorenz R, Siess W. | 07/17/2021 |
| Nonredundant Roles of Platelet Glycoprotein VI and Integrin alphaIIbbeta3 in Fibrin-Mediated Microthrombus Formation. | Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation.
Perrella G, Huang J, Provenzale I, Swieringa F, Heubel-Moenen FCJI, Farndale RW, Roest M, van der Meijden PEJ, Thomas M, Ariëns RAS, Jandrot-Perrus M, Watson SP, Heemskerk JWM. | 06/5/2021 |
| Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions. | Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions.
Nagy M, Perrella G, Dalby A, Becerra MF, Garcia Quintanilla L, Pike JA, Morgan NV, Gardiner EE, Heemskerk JWM, Azócar L, Miquel JF, Mezzano D, Watson SP., Free PMC Article | 05/22/2021 |
| Genetic variation of platelet glycoprotein VI and the risk of venous thromboembolism. | Genetic variation of platelet glycoprotein VI and the risk of venous thromboembolism.
Skille H, Paulsen B, Hveem K, Gabrielsen ME, Brumpton B, Hindberg K, Gran OV, Rosendaal FR, Brækkan SK, Hansen JB., Free PMC Article | 05/8/2021 |
| Association between Platelet-Specific Collagen Receptor Glycoprotein 6 Gene Variants, Selected Biomarkers, and Recurrent Pregnancy Loss in Korean Women. | Association between Platelet-Specific Collagen Receptor Glycoprotein 6 Gene Variants, Selected Biomarkers, and Recurrent Pregnancy Loss in Korean Women.
An HJ, Ahn EH, Kim JO, Ryu CS, Park HS, Cho SH, Kim JH, Lee WS, Lee JR, Kim YR, Kim NK., Free PMC Article | 04/3/2021 |
| GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen alphaC-Region. | GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region.
Xu RG, Gauer JS, Baker SR, Slater A, Martin EM, McPherson HR, Duval C, Manfield IW, Bonna AM, Watson SP, Ariëns RAS., Free PMC Article | 03/20/2021 |
| Physical proximity and functional cooperation of glycoprotein 130 and glycoprotein VI in platelet membrane lipid rafts. | Physical proximity and functional cooperation of glycoprotein 130 and glycoprotein VI in platelet membrane lipid rafts.
Houck KL, Yuan H, Tian Y, Solomon M, Cramer D, Liu K, Zhou Z, Wu X, Zhang J, Oehler V, Dong JF. | 08/22/2020 |
| especially higher occurrence of 4 nonsynonymous variants within the coding region, support the idea that GP6 polymorphisms are associated with the platelet hyperaggregability accompanied by fetal loss. | Glycoprotein VI Gene Variants Affect Pregnancy Loss in Patients With Platelet Hyperaggregability.
Sokol J, Skerenova M, Biringer K, Simurda T, Kubisz P, Stasko J., Free PMC Article | 06/13/2020 |
| Platelet membrane lipid rafts protein composition varies following GPVI and CLEC-2 receptors activation. | Platelet membrane lipid rafts protein composition varies following GPVI and CLEC-2 receptors activation.
Izquierdo I, Barrachina MN, Hermida-Nogueira L, Casas V, Eble JA, Carrascal M, Abián J, García Á. | 05/30/2020 |
| Up-regulation of GPVI signalling and GPVI platelet surface expression occurs in obese patients, resulting in increased platelet activation. | GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity.
Barrachina MN, Sueiro AM, Izquierdo I, Hermida-Nogueira L, Guitián E, Casanueva FF, Farndale RW, Moroi M, Jung SM, Pardo M, García Á., Free PMC Article | 04/18/2020 |
| The study showed a significant association of genetic polymorphisms (CYP2C19*2 G>A and GPVI T>C) with aspirin and clopidogrel dual antiplatelet therapy non-responsiveness in myocardial infarction patients.. | Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction.
Pandey CP, Misra A, Negi MPS, Kanuri BN, Chhonker YS, Bhatta RS, Narain VS, Dikshit M., Free PMC Article | 04/11/2020 |
| The role for GPVI in platelet function in inflammation and in the evolution and treatment of major illnesses such as rheumatoid arthritis, cancer and sepsis is discussed. [review] | Clinical significance of altered collagen-receptor functioning in platelets with emphasis on glycoprotein VI.
Nurden AT. | 03/28/2020 |