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    TRPV2 transient receptor potential cation channel subfamily V member 2 [ Homo sapiens (human) ]

    Gene ID: 51393, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.

    Tyrosine phosphorylation and palmitoylation of TRPV2 ion channel tune microglial beta-amyloid peptide phagocytosis.
    Yang S, Du Y, Li Y, Tang Q, Zhang Y, Zhao X., Free PMC Article

    10/23/2024
    TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity.

    TRPV2: a universal regulator in cellular physiology with a yet poorly defined thermosensitivity.
    Fricke TC, Leffler A., Free PMC Article

    09/24/2024
    TCAF1 promotes TRPV2-mediated Ca[2+] release in response to cytosolic DNA to protect stressed replication forks.

    TCAF1 promotes TRPV2-mediated Ca(2+) release in response to cytosolic DNA to protect stressed replication forks.
    Kong L, Cheng C, Cheruiyot A, Yuan J, Yang Y, Hwang S, Foust D, Tsao N, Wilkerson E, Mosammaparast N, Major MB, Piston DW, Li S, You Z., Free PMC Article

    09/20/2024
    TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells.

    TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells.
    Dunne OM, Martin SL, Sergeant GP, McAuley DF, O'Kane CM, Button B, McGarvey LP, Lundy FT., Free PMC Article

    05/22/2024
    Ion channel TRPV2 is critical in enhancing B cell activation and function.

    Ion channel TRPV2 is critical in enhancing B cell activation and function.
    Li C, Zhao M, Liu X, Li Y, Xu B, Zhou L, Sun X, Sun W, Kang N, Ji Z, Li T, An H, Wang F, Wu C, Ye JY, Zhang JR, Wang Q, Zhao X, Li Z, Liu W., Free PMC Article

    02/16/2024
    Effects of TRPV2 on the Expression of PD-L1 and Its Binding Ability to PD-1 in Gastric Cancer.

    Effects of TRPV2 on the Expression of PD-L1 and Its Binding Ability to PD-1 in Gastric Cancer.
    Shiozaki A, Fukami T, Shimizu H, Kosuga T, Kudou M, Takemoto K, Katsurahara K, Nishibeppu K, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Otsuji E.

    11/13/2023
    TRPV2, a novel player in the human ovary and human granulosa cells.

    TRPV2, a novel player in the human ovary and human granulosa cells.
    Eubler K, Caban KM, Dissen GA, Berg U, Berg D, Herrmann C, Kreitmair N, Tiefenbacher A, Fröhlich T, Mayerhofer A., Free PMC Article

    09/12/2023
    The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential.

    The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential.
    Shoji KF, Bayet E, Leverrier-Penna S, Le Devedec D, Mallavialle A, Marionneau-Lambot S, Rambow F, Perret R, Joussaume A, Viel R, Fautrel A, Khammari A, Constantin B, Tartare-Deckert S, Penna A., Free PMC Article

    04/6/2023
    Hypo-osmolarity induces apoptosis resistance via TRPV2-mediated AKT-Bcl-2 pathway.

    Hypo-osmolarity induces apoptosis resistance via TRPV2-mediated AKT-Bcl-2 pathway.
    Urushima H, Matsubara T, Miyakoshi M, Kimura S, Yuasa H, Yoshizato K, Ikeda K., Free PMC Article

    03/4/2023
    Impact of the TRPV2 Inhibitor on Advanced Heart Failure in Patients with Muscular Dystrophy: Exploratory Study of Biomarkers Related to the Efficacy of Tranilast.

    Impact of the TRPV2 Inhibitor on Advanced Heart Failure in Patients with Muscular Dystrophy: Exploratory Study of Biomarkers Related to the Efficacy of Tranilast.
    Takahashi C, Oishi M, Iwata Y, Maekawa K, Matsumura T., Free PMC Article

    02/16/2023
    Predictive value of TRPV2 expression from peripheral blood mononuclear cells on the early recurrence of atrial fibrillation after radiofrequency catheter ablation.

    Predictive value of TRPV2 expression from peripheral blood mononuclear cells on the early recurrence of atrial fibrillation after radiofrequency catheter ablation.
    Ling X, Wang J, Qin X, Lin C, Jie W, Chen Y, Fu D, Yang Y, Meng Q, Lin J, Liu H, Li T, Guo J., Free PMC Article

    12/24/2022
    Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.

    Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
    Zhang L, Simonsen C, Zimova L, Wang K, Moparthi L, Gaudet R, Ekoff M, Nilsson G, Hellmich UA, Vlachova V, Gourdon P, Zygmunt PM., Free PMC Article

    12/17/2022
    Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma.

    Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma.
    Huang R, Li S, Tian C, Zhou P, Zhao H, Xie W, Xiao J, Wang L, Habimana JD, Lin Z, Yang Y, Cheng N, Li Z., Free PMC Article

    10/22/2022
    Extent of intrinsic disorder and NMR chemical shift assignments of the distal N-termini from human TRPV1, TRPV2 and TRPV3 ion channels.

    Extent of intrinsic disorder and NMR chemical shift assignments of the distal N-termini from human TRPV1, TRPV2 and TRPV3 ion channels.
    Wiedemann C, Goretzki B, Merz ZN, Tebbe F, Schmitt P, Hellmich UA., Free PMC Article

    10/15/2022
    ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2.

    ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2.
    Sun MC, Fang K, Li ZX, Chu Y, Xu AP, Zhao ZY, Leng ZY, Zhang YW, Zhang ZH, Zhang L, Chen T, Xu MD., Free PMC Article

    07/23/2022
    Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment.

    Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment.
    Chen L, Chen Y, Ding W, Zhan T, Zhu J, Zhang L, Wang H, Shen B, Wang Y., Free PMC Article

    04/30/2022
    TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-beta Signaling Pathway.

    TRPV2 Promotes Cell Migration and Invasion in Gastric Cancer via the Transforming Growth Factor-β Signaling Pathway.
    Kato S, Shiozaki A, Kudou M, Shimizu H, Kosuga T, Ohashi T, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Otsuji E.

    04/16/2022
    TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.

    TRPV2-spike protein interaction mediates the entry of SARS-CoV-2 into macrophages in febrile conditions.
    Xu J, Yang Y, Hou Z, Jia H, Wang Y., Free PMC Article

    07/3/2021
    TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton.

    TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton.
    Yadav M, Goswami C., Free PMC Article

    04/3/2021
    The Effects of Cannabidiol and Prognostic Role of TRPV2 in Human Endometrial Cancer.

    The Effects of Cannabidiol and Prognostic Role of TRPV2 in Human Endometrial Cancer.
    Marinelli O, Morelli MB, Annibali D, Aguzzi C, Zeppa L, Tuyaerts S, Amantini C, Amant F, Ferretti B, Maggi F, Santoni G, Nabissi M., Free PMC Article

    02/20/2021
    The expression and role of TRPV2 in esophageal squamous cell carcinoma.

    The expression and role of TRPV2 in esophageal squamous cell carcinoma.
    Kudou M, Shiozaki A, Yamazato Y, Katsurahara K, Kosuga T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, Marunaka Y, Otsuji E., Free PMC Article

    10/31/2020
    TRPV2 channel as a possible drug target for the treatment of heart failure.

    TRPV2 channel as a possible drug target for the treatment of heart failure.
    Iwata Y, Ito S, Wakabayashi S, Kitakaze M.

    09/26/2020
    The TRPV2 cation channels: from urothelial cancer invasiveness to glioblastoma multiforme interactome signature.

    The TRPV2 cation channels: from urothelial cancer invasiveness to glioblastoma multiforme interactome signature.
    Santoni G, Amantini C, Maggi F, Marinelli O, Santoni M, Nabissi M, Morelli MB.

    09/26/2020
    Trafficking of Stretch-Regulated TRPV2 and TRPV4 Channels Inferred Through Interactomics.

    Trafficking of Stretch-Regulated TRPV2 and TRPV4 Channels Inferred Through Interactomics.
    Doñate-Macián P, Enrich-Bengoa J, Dégano IR, Quintana DG, Perálvarez-Marín A., Free PMC Article

    08/29/2020
    A methionine-dependent redox sensitivity of TRPV2 which may be an important endogenous mechanism for regulation of TRPV2 activity and account for its pivotal role for phagocytosis in macrophages.

    Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2.
    Fricke TC, Echtermeyer F, Zielke J, de la Roche J, Filipovic MR, Claverol S, Herzog C, Tominaga M, Pumroy RA, Moiseenkova-Bell VY, Zygmunt PM, Leffler A, Eberhardt MJ., Free PMC Article

    05/2/2020
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