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    YTHDF2 YTH N6-methyladenosine RNA binding protein F2 [ Homo sapiens (human) ]

    Gene ID: 51441, updated on 3-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    lncRNA JPX Promotes Tumor Progression by Interacting with and Destabilizing YTHDF2 in Cutaneous Melanoma.

    lncRNA JPX Promotes Tumor Progression by Interacting with and Destabilizing YTHDF2 in Cutaneous Melanoma.
    Luo D, Tang H, Tan L, Zhang L, Wang L, Cheng Q, Lei X, Wu J.

    09/3/2024
    Smooth Muscle Ythdf2 Abrogation Ameliorates Pulmonary Vascular Remodeling by Regulating Myadm Transcript Stability.

    Smooth Muscle Ythdf2 Abrogation Ameliorates Pulmonary Vascular Remodeling by Regulating Myadm Transcript Stability.
    Wang J, Shen Y, Zhang Y, Lin D, Wang Q, Sun X, Wei D, Shen B, Chen J, Ji Y, Fulton D, Yu Y, Chen F, Hu L.

    08/16/2024
    Hereditary spastic paraparesis type 18 (SPG18): new ERLIN2 variants in a series of Italian patients, shedding light upon genetic and phenotypic variability.

    Hereditary spastic paraparesis type 18 (SPG18): new ERLIN2 variants in a series of Italian patients, shedding light upon genetic and phenotypic variability.
    Cioffi E, Gioiosa V, Tessa A, Petrucci A, Trovato R, Santorelli FM, Casali C., Free PMC Article

    08/15/2024
    N[6]-methyladenosine (m[6]A) reader YTHDF2 accelerates endothelial cells ferroptosis in cerebrovascular atherosclerosis.

    N(6)-methyladenosine (m(6)A) reader YTHDF2 accelerates endothelial cells ferroptosis in cerebrovascular atherosclerosis.
    Li J, Zou C, Zhang Z, Xue F.

    08/15/2024
    BCLAF1 drives esophageal squamous cell carcinoma progression through regulation of YTHDF2-dependent SIX1 mRNA degradation.

    BCLAF1 drives esophageal squamous cell carcinoma progression through regulation of YTHDF2-dependent SIX1 mRNA degradation.
    Zhang P, Zhang W, Wang X, Li L, Lin Y, Wu N, Mao R, Lin J, Kang M, Ding C.

    08/6/2024
    [Porphyromonas gingivalis infection facilitates immune escape of esophageal cancer by enhancing YTHDF2-mediated Fas degradation].

    [Porphyromonas gingivalis infection facilitates immune escape of esophageal cancer by enhancing YTHDF2-mediated Fas degradation].
    Yang Z, Zhang X, Zhang X, Liu Y, Zhang J, Yuan X., Free PMC Article

    08/2/2024
    Negative Regulation of LINC01013 by METTL3 and YTHDF2 Enhances the Osteogenic Differentiation of Senescent Pre-Osteoblast Cells Induced by Hydrogen Peroxide.

    Negative Regulation of LINC01013 by METTL3 and YTHDF2 Enhances the Osteogenic Differentiation of Senescent Pre-Osteoblast Cells Induced by Hydrogen Peroxide.
    Song J, Wang Y, Zhu Z, Wang W, Yang H, Shan Z.

    05/31/2024
    YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation.

    YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation.
    Zhao X, Lv S, Li N, Zou Q, Sun L, Song T., Free PMC Article

    05/8/2024
    YTHDF2 promotes gastric cancer progression and enhances chemoradiotherapy resistance.

    YTHDF2 promotes gastric cancer progression and enhances chemoradiotherapy resistance.
    Yang J, Chen Y, He Y, Da M.

    05/3/2024
    WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.

    WTAP enhances the instability of SYTL1 mRNA caused by YTHDF2 in bladder cancer.
    Wang J, Luo J, Wu X, Li Z.

    04/26/2024
    FTO promotes the progression of retinoblastoma through YTHDF2-dependent N6-methyladenosine modification in E2F3.

    FTO promotes the progression of retinoblastoma through YTHDF2-dependent N6-methyladenosine modification in E2F3.
    Xie W, Shao Y, Bo Q, Li Z, Yu Q, Wang L, Wu G.

    04/25/2024
    YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis.

    YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis.
    Wen J, Xue L, Wei Y, Liang J, Jia W, Yong T, Chu L, Li H, Han S, Liao J, Chen Z, Liu Y, Liu Q, Ding Z, Liang H, Gan L, Chen X, Huang Z, Zhang B., Free PMC Article

    04/15/2024
    METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy.

    METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy.
    Wang F, Bai J, Zhang X, Wang D, Zhang X, Xue J, Chen H, Wang S, Chi B, Li J, Ma X., Free PMC Article

    03/13/2024
    FOXM1 Participates in Scleral Remodeling in Myopia by Upregulating APOA1 Expression Through METTL3/YTHDF2.

    FOXM1 Participates in Scleral Remodeling in Myopia by Upregulating APOA1 Expression Through METTL3/YTHDF2.
    Xue M, Li B, Lu Y, Zhang L, Yang B, Shi L., Free PMC Article

    01/11/2024
    Epitranscriptional regulation of TGF-beta pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.

    Epitranscriptional regulation of TGF-β pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.
    Wang L, Si W, Yu X, Piffko A, Dou X, Ding X, Bugno J, Yang K, Wen C, Zhang L, Chen D, Huang X, Wang J, Arina A, Pitroda S, Chmura SJ, He C, Liang HL, Weichselbaum R., Free PMC Article

    12/20/2023
    YTHDF2 promotes gallbladder cancer progression and gemcitabine resistance via m6A-dependent DAPK3 degradation.

    YTHDF2 promotes gallbladder cancer progression and gemcitabine resistance via m6A-dependent DAPK3 degradation.
    Bai X, Chen J, Zhang W, Zhou S, Dong L, Huang J, He X., Free PMC Article

    11/16/2023
    METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.

    METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in endometriosis-related infertility.
    Li X, Jin J, Long X, Weng R, Xiong W, Liang J, Liu J, Sun J, Cai X, Zhang L, Liu Y., Free PMC Article

    11/1/2023
    YTHDF2 facilitates aggresome formation via UPF1 in an m[6]A-independent manner.

    YTHDF2 facilitates aggresome formation via UPF1 in an m(6)A-independent manner.
    Hwang HJ, Park TL, Kim HI, Park Y, Kim G, Song C, Cho WK, Kim YK., Free PMC Article

    10/13/2023
    HSP90beta Impedes STUB1-Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma.

    HSP90β Impedes STUB1-Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma.
    Liao Y, Liu Y, Yu C, Lei Q, Cheng J, Kong W, Yu Y, Zhuang X, Sun W, Yin S, Cai G, Huang H., Free PMC Article

    10/11/2023
    YTHDF2 negatively correlates with tumor immune infiltration in small cell lung cancer.

    YTHDF2 negatively correlates with tumor immune infiltration in small cell lung cancer.
    Chen G, Ren D, Wang Y, Wang H, Zhang J, Yang S.

    08/11/2023
    Diagnostic value and immune infiltration characterization of YTHDF2 as a critical m6A regulator in osteoarthritic synovitis.

    Diagnostic value and immune infiltration characterization of YTHDF2 as a critical m6A regulator in osteoarthritic synovitis.
    Bian A, Wang C, Zhang H, Yan Y, Zhang L, Cheng W., Free PMC Article

    08/3/2023
    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.

    YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
    Wang L, Dou X, Chen S, Yu X, Huang X, Zhang L, Chen Y, Wang J, Yang K, Bugno J, Pitroda S, Ding X, Piffko A, Si W, Chen C, Jiang H, Zhou B, Chmura SJ, Luo C, Liang HL, He C, Weichselbaum RR., Free PMC Article

    07/19/2023
    ALKBH5/YTHDF2-mediated m6A modification of circAFF2 enhances radiosensitivity of colorectal cancer by inhibiting Cullin neddylation.

    ALKBH5/YTHDF2-mediated m6A modification of circAFF2 enhances radiosensitivity of colorectal cancer by inhibiting Cullin neddylation.
    Shao Y, Liu Z, Song X, Sun R, Zhou Y, Zhang D, Sun H, Huang J, Wu C, Gu W, Zheng X, Jiang J., Free PMC Article

    07/7/2023
    The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I-Mediated Immune Response.

    The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I-Mediated Immune Response.
    Zhang L, Li Y, Zhou L, Zhou H, Ye L, Ou T, Hong H, Zheng S, Zhou Z, Wu K, Yan Z, Thiery JP, Cui J, Wu S., Free PMC Article

    06/13/2023
    N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21[cip1/waf1]/CDK2-Cyclin E1 axis-mediated cell cycle transition.

    N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
    Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A., Free PMC Article

    05/19/2023
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