| CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-kappaB pathway. | CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway.
Gao W, Liu R, Huang K, Fu W, Wang A, Du G, Tang H, Yin L, Yin ZS., Free PMC Article | 04/29/2024 |
| Circ_CHMP5 aggravates oxidized low-density lipoprotein-induced damage to human umbilical vein endothelial cells through miR-516b-5p/TGFbetaR2 axis. | Circ_CHMP5 aggravates oxidized low-density lipoprotein-induced damage to human umbilical vein endothelial cells through miR-516b-5p/TGFβR2 axis.
Wang Y, Liu P, Chen X, Yang W. | 01/12/2024 |
| Vps60 initiates alternative ESCRT-III filaments. | Vps60 initiates alternative ESCRT-III filaments.
Pfitzner AK, Zivkovic H, Bernat-Silvestre C, West M, Peltier T, Humbert F, Odorizzi G, Roux A., Free PMC Article | 11/13/2023 |
| Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase. | Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase.
Pashkova N, Yu L, Schnicker NJ, Tseng CC, Gakhar L, Katzmann DJ, Piper RC., Free PMC Article | 03/26/2022 |
| Our findings show that CHMP5 is a direct target of MIR429 in human colon cancer cell lines and suggest that CHMP5 up-regulation as a result of reduced MIR429 expression in DSS-induced mice colitis tissues and human UC tissues may restrict apoptosis and promote cell proliferation. | MicroRNA 429 regulates the expression of CHMP5 in the inflammatory colitis and colorectal cancer cells.
Mo JS, Han SH, Yun KJ, Chae SC. | 02/23/2019 |
| CHMP5 might be involved in the homeostatic regulation of TCR on the cell surface, presumably through TCR recycling or degradation. Thus CHMP5 is implicated in TCR-mediated signaling. | Charged MVB protein 5 is involved in T-cell receptor signaling.
Wi SM, Min Y, Lee KY., Free PMC Article | 10/22/2016 |
| ESCRT-III protein CHMP5 inhibits LIP5-mediated VPS4 activation by inducing a moderate conformational change within LIP5. | A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.
Vild CJ, Li Y, Guo EZ, Liu Y, Xu Z., Free PMC Article | 05/30/2015 |
| after CHMP5 inhibition, both Granzyme B/Perforin apoptotic pathway and apoptosis-inducing factor-mediated necrotic pathway were activated, while autophagic pathway was not activated | The role of charged multivesicular body protein 5 in programmed cell death in leukemic cells.
Wang H, Liu J, Wang F, Chen M, Xiao Z, Ouyang R, Fei A, Shen Y, Pan S. | 11/2/2013 |
| PNAS-2 was shown to be anti-apoptotic and may participate in leukemogenesis | PNAS-2: a novel gene probably participating in leukemogenesis.
Wang HR, Gu CH, Zhu JY, Han JY, Zhong H, Chen FY, Ouyang RR. | 09/15/2010 |
| pnas-2 is specifically up-regulated in acute leukemia patients. | [Expression spectra of apoptosis-related gene pnas-2].
Wang HR, Zhu JY, Gu CH, Zhong H, Zhong JH, Han JY, Chen FY, Ouyan RR. | 01/25/2010 |
| The pnas-2 gene may be closely related with apotosis of arsenic sulfide treated APL cells. | [Correlation between expression of apoptosis-related gene pnas-2 and leukemia].
Huang HH, Zhu JY, Zhong JH, Wang HR, Zhong H, Han JY, Chen FY. | 01/21/2010 |