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    RTRAF RNA transcription, translation and transport factor [ Homo sapiens (human) ]

    Gene ID: 51637, updated on 27-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    An in silico prediction of interaction models of influenza A virus PA and human C14orf166 protein from yeast-two-hybrid screening data.

    An in silico prediction of interaction models of influenza A virus PA and human C14orf166 protein from yeast-two-hybrid screening data.
    Çağlayan E, Turan K.

    10/30/2023
    Molecular architecture of the human tRNA ligase complex.

    Molecular architecture of the human tRNA ligase complex.
    Kroupova A, Ackle F, Asanović I, Weitzer S, Boneberg FM, Faini M, Leitner A, Chui A, Aebersold R, Martinez J, Jinek M., Free PMC Article

    01/29/2022
    the two structural homologs FAM98A and FAM98B included in a novel complex with DDX1 and C14orf166 are required for PRMT1 expression in colorectal cancer cell lines

    FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression.
    Akter KA, Mansour MA, Hyodo T, Senga T.

    11/4/2017
    C14ORF166 may represent a biomarker of pelvic lymph node metastasis in uterine cervical cancer

    C14ORF166 overexpression is associated with pelvic lymph node metastasis and poor prognosis in uterine cervical cancer.
    Zhang W, Ou J, Lei F, Hou T, Wu S, Niu C, Xu L, Zhang Y., Free PMC Article

    02/18/2017
    C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles.

    hCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles.
    Rodriguez-Frandsen A, de Lucas S, Pérez-González A, Pérez-Cidoncha M, Roldan-Gomendio A, Pazo A, Marcos-Villar L, Landeras-Bueno S, Ortín J, Nieto A., Free PMC Article

    12/24/2016
    C14orf166 promotes bladder cancer cell proliferation and can be a novel prognostic biomarker for patients with bladder cancer.

    C14orf166 is a high-risk biomarker for bladder cancer and promotes bladder cancer cell proliferation.
    Chen M, Ye Y, Zou B, Guo S, Zhou F, Lu K, Liu J, Xu Z, Han H, Liu Z, Li Y, Yao K, Liu C, Qin Z., Free PMC Article

    11/12/2016
    C14orf166 could be a novel prognostic biomarker of breast cancer, it also contributes to cell proliferation by regulating G1/S transition.

    C14orf166 overexpression correlates with tumor progression and poor prognosis of breast cancer.
    Cheang TY, Zhou HY, Chen W, Zhang B, Liu L, Yang J, Wang S, Li H., Free PMC Article

    11/12/2016
    Overexpression of chromosome 14 open reading frame 166 correlates with disease progression in nasopharyngeal carcinoma.

    Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC.
    Yang L, Li F, Lei F, Wang Y, Wu S, Song L, Chen Y.

    01/30/2016
    hCLE/C14orf166 associates with DDX1, HSPC117, and FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.

    hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
    Pérez-González A, Pazo A, Navajas R, Ciordia S, Rodriguez-Frandsen A, Nieto A., Free PMC Article

    02/14/2015
    Silencing of CLE causes reduction of influenza A virus polymerase activity, viral RNA transcription and replication, virus titer, and viral particle production.

    Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication.
    Rodriguez A, Pérez-González A, Nieto A., Free PMC Article

    12/17/2011
    spatial interactions of hnRNPH1, NF45, and C14orf166 with HCVc174 likely modulate HCV or cellular functions during acute and chronic HCV infection

    Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein.
    Lee JW, Liao PC, Young KC, Chang CL, Chen SS, Chang TT, Lai MD, Wang SW.

    12/17/2011
    c14orf166 was identified asa novel metastasis-associated protein, and the roles of radixin, moesin and c14orf166 in pancreatic cancer metastasis deserve further investigations.

    Proteomic profiling in pancreatic cancer with and without lymph node metastasis.
    Cui Y, Wu J, Zong M, Song G, Jia Q, Jiang J, Han J.

    01/21/2010
    A novel protein CGI-99 is isolated, which may be involved in the functional regulation of human ninein in the centrosome structure and may also be important in brain development and tumorigenesis.

    A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors.
    Howng SL, Hsu HC, Cheng TS, Lee YL, Chang LK, Lu PJ, Hong YR.

    01/21/2010
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