| Histone demethylase KDM3B protects against ferroptosis by upregulating SLC7A11. | Histone demethylase KDM3B protects against ferroptosis by upregulating SLC7A11.
Wang Y, Zhao Y, Wang H, Zhang C, Wang M, Yang Y, Xu X, Hu Z., Free PMC Article | 07/24/2021 |
| JMJD1B, a novel player in histone H3 and H4 processing to ensure genome stability. | JMJD1B, a novel player in histone H3 and H4 processing to ensure genome stability.
Saavedra F, Gurard-Levin ZA, Rojas-Villalobos C, Vassias I, Quatrini R, Almouzni G, Loyola A., Free PMC Article | 04/24/2021 |
| Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer. | Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer.
Saraç H, Morova T, Pires E, McCullagh J, Kaplan A, Cingöz A, Bagci-Onder T, Önder T, Kawamura A, Lack NA., Free PMC Article | 11/28/2020 |
| Histone lysine demethylase 3B (KDM3B) regulates the propagation of autophagy via transcriptional activation of autophagy-related genes. | Histone lysine demethylase 3B (KDM3B) regulates the propagation of autophagy via transcriptional activation of autophagy-related genes.
Jung H, Seo SB., Free PMC Article | 09/26/2020 |
| pathogenic variants in KDM3B cause a syndrome characterized by intellectual disability, short stature, and facial dysmorphism | De Novo and Inherited Pathogenic Variants in KDM3B Cause Intellectual Disability, Short Stature, and Facial Dysmorphism.
Diets IJ, van der Donk R, Baltrunaite K, Waanders E, Reijnders MRF, Dingemans AJM, Pfundt R, Vulto-van Silfhout AT, Wiel L, Gilissen C, Thevenon J, Perrin L, Afenjar A, Nava C, Keren B, Bartz S, Peri B, Beunders G, Verbeek N, van Gassen K, Thiffault I, Cadieux-Dion M, Huerta-Saenz L, Wagner M, Konstantopoulou V, Vodopiutz J, Griese M, Boel A, Callewaert B, Brunner HG, Kleefstra T, Hoogerbrugge N, de Vries BBA, Hwa V, Dauber A, Hehir-Kwa JY, Kuiper RP, Jongmans MCJ., Free PMC Article | 02/8/2020 |
| The results implicate KDM3B as a crucial epigenetic factor in cell cycle regulation that manipulates chromatin dynamics and transcription in hepatocarcinoma. | Histone demethylase KDM3B regulates the transcriptional network of cell-cycle genes in hepatocarcinoma HepG2 cells.
An MJ, Kim DH, Kim CH, Kim M, Rhee S, Seo SB, Kim JW. | 06/8/2019 |
| we found that KDM3B exhibits potential tumor-suppressive activity and transcriptionally modulates HOXA1 expression via RARE in AML. | KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.
Xu X, Nagel S, Quentmeier H, Wang Z, Pommerenke C, Dirks WG, Macleod RAF, Drexler HG, Hu Z. | 08/4/2018 |
| H3K9 demethylase KDM3B represses transcription of the angiogenesis regulatory gene, ANGPT1. | Transcriptional repression of ANGPT1 by histone H3K9 demethylase KDM3B.
Han A, Chae YC, Park JW, Kim KB, Kim JY, Seo SB., Free PMC Article | 04/30/2016 |
| High expression of KDM3B and KDM5A is associated with a better prognosis (no recurrence after mastectomy p=0.005 and response to docetaxel p=0.005)in breast cancer patients. | Histone lysine demethylases in breast cancer.
Paolicchi E, Crea F, Farrar WL, Green JE, Danesi R., Free PMC Article | 09/28/2013 |
| evidence that the H3K9-me1/2 demethylase KDM3B might play a role in leukemogenesis via activation of lmo2 through interdependent actions with the histone acetyltransferase complex containing CBP | KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.
Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB., Free PMC Article | 09/22/2012 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| A novel nuclear protein, 5qNCA is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31. | A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.
Hu Z, Gomes I, Horrigan SK, Kravarusic J, Mar B, Arbieva Z, Chyna B, Fulton N, Edassery S, Raza A, Westbrook CA. | 02/13/2002 |