| IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy. | IGF2BP3-stabilized CAMK1 regulates the mitochondrial dynamics of renal tubule to alleviate diabetic nephropathy.
Yuan D, Li H, Dai W, Zhou X, Zhou W, He L. | 02/22/2024 |
| A molecular complex of Cav1.2/CaMKK2/CaMK1a in caveolae is responsible for vascular remodeling via excitation-transcription coupling. | A molecular complex of Ca(v)1.2/CaMKK2/CaMK1a in caveolae is responsible for vascular remodeling via excitation-transcription coupling.
Suzuki Y, Ozawa T, Kurata T, Nakajima N, Zamponi GW, Giles WR, Imaizumi Y, Yamamura H., Free PMC Article | 05/7/2022 |
| report that Parvalbumin positive interneurons employ a novel CaMK-dependent pathway to trigger CREB phosphorylation and gene expression. | Excitation-Transcription Coupling in Parvalbumin-Positive Interneurons Employs a Novel CaM Kinase-Dependent Pathway Distinct from Excitatory Neurons.
Cohen SM, Ma H, Kuchibhotla KV, Watson BO, Buzsáki G, Froemke RC, Tsien RW., Free PMC Article | 06/24/2017 |
| the CaMKK-CaMKIalpha cascade is required for the axonal growth effect of Wnt5a during neuronal polarization. | Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization.
Horigane S, Ageta-Ishihara N, Kamijo S, Fujii H, Okamura M, Kinoshita M, Takemoto-Kimura S, Bito H., Free PMC Article | 10/22/2016 |
| CaMKIalpha regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation. | CaMKIα regulates AMP kinase-dependent, TORC-1-independent autophagy during lipopolysaccharide-induced acute lung neutrophilic inflammation.
Guo L, Stripay JL, Zhang X, Collage RD, Hulver M, Carchman EH, Howell GM, Zuckerbraun BS, Lee JS, Rosengart MR., Free PMC Article | 05/25/2013 |
| CaMKI vies with CRM1/exportin 1 for access to a nuclear export signal, and assembly of a CaMKI-14-3-3 zeta-CCTalpha complex is a key effector mechanism that drives nuclear CCTalpha translocation. | Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal.
Agassandian M, Chen BB, Pulijala R, Kaercher L, Glasser JR, Mallampalli RK., Free PMC Article | 12/22/2012 |
| CaMKIalpha signaling is integral to the Mvarphi responding to LPS and may also be operant in vivo in regulating the inflammation and organ dysfunction consequent to sepsis. | Calcium/calmodulin-dependent protein kinase (CaMK) Ialpha mediates the macrophage inflammatory response to sepsis.
Zhang X, Guo L, Collage RD, Stripay JL, Tsung A, Lee JS, Rosengart MR., Free PMC Article | 10/15/2011 |
| Inflammatory acidic environments activate Trpv1, leading to an up-regulation of CGRP expression via CaMK-CREB cascade, a series of events that may be associated with inflammatory pain. | Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain.
Nakanishi M, Hata K, Nagayama T, Sakurai T, Nishisho T, Wakabayashi H, Hiraga T, Ebisu S, Yoneda T., Free PMC Article | 11/27/2010 |
| Our results reveal a previously unrecognized CaM-signaling pathway that endows the VSNs with a mechanism for adjusting gain and sensitivity of chemosensory signaling in the VNO. | Ca2+ -calmodulin feedback mediates sensory adaptation and inhibits pheromone-sensitive ion channels in the vomeronasal organ.
Spehr J, Hagendorf S, Weiss J, Spehr M, Leinders-Zufall T, Zufall F., Free PMC Article | 01/21/2010 |
| Data identify CaMK1beta as a novel regulator of osteoblast proliferation, via mechanisms that may at least in part involve c-Fos, thus implicating CaMK1beta in the regulation of bone and cartilage development. | Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro.
Pedersen ME, Fortunati D, Nielsen M, Brorson SH, Lekva T, Nissen-Meyer LS, Gautvik VT, Shahdadfar A, Gautvik KM, Jemtland R. | 01/21/2010 |
| CaMKI transcriptionally cooperates with NUR77, but not steroidogenic factor 1, to enhance StAR promoter activity in Leydig cells | The orphan nuclear receptor NUR77 regulates hormone-induced StAR transcription in Leydig cells through cooperation with Ca2+/calmodulin-dependent protein kinase I.
Martin LJ, Boucher N, Brousseau C, Tremblay JJ., Free PMC Article | 01/21/2010 |
| CaMKI/IIgamma have roles in osteoclast differentiation and bone resportion via RANKL. | Calcium/calmodulin-dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL).
Ang ES, Zhang P, Steer JH, Tan JW, Yip K, Zheng MH, Joyce DA, Xu J. | 01/21/2010 |
| ERK activation and neurite outgrowth in response to depolarization are mediated by CaMKK activation of CaMKI | Calcium activation of ERK mediated by calmodulin kinase I.
Schmitt JM, Wayman GA, Nozaki N, Soderling TR. | 01/21/2010 |
| Full-length cDNA encoded am amino acid sequence similar to that of calmodulin kinase I. | Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV.
Ohmae S, Takemoto-Kimura S, Okamura M, Adachi-Morishima A, Nonaka M, Fuse T, Kida S, Tanji M, Furuyashiki T, Arakawa Y, Narumiya S, Okuno H, Bito H. | 01/21/2010 |
| calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences | Proteomic analysis of calcium/calmodulin-dependent protein kinase I and IV in vitro substrates reveals distinct catalytic preferences.
Corcoran EE, Joseph JD, MacDonald JA, Kane CD, Haystead TA, Means AR. | 01/21/2010 |
| Interaction of MARK2 with CaMKI results in a novel, calcium-dependent pathway that plays an important role in neuronal differentiation. | A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth.
Uboha NV, Flajolet M, Nairn AC, Picciotto MR., Free PMC Article | 01/21/2010 |