| Case report: Deep sequencing and long-read genome sequencing refine prior genetic analyses in families with apparent gonadal mosaicism in PIK3CD-related activated PI3K delta syndrome. | Case report: Deep sequencing and long-read genome sequencing refine prior genetic analyses in families with apparent gonadal mosaicism in PIK3CD-related activated PI3K delta syndrome.
Orellana H, Yan J, Paul A, Tokita M, Ding Y, Ghosh R, Lewis KL, Davis J, Jamal L, Jodarski C, Similuk M, Saucier N, Zhu Z, Wang Y, Wu S, Ruggieri J, Su HC, Uzel G, Nahas S, Cooper M, Walkiewicz MA., Free PMC Article | 10/31/2024 |
| circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD. | circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD.
Fu XL, He FT, Li MH, Fu CY, Chen JZ. | 07/17/2024 |
| PI3Kdelta Mediates Fibrosis by Patient-Derived Vitreous. | PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous.
Liu D, Yan B, Yin Y, Chen F, Guo C, Li Q, Liu J, Pu L, Wu W, Luo J. | 04/25/2024 |
| STMN1 promotes cell malignancy and bortezomib resistance of multiple myeloma cell lines via PI3K/AKT signaling. | STMN1 promotes cell malignancy and bortezomib resistance of multiple myeloma cell lines via PI3K/AKT signaling.
Wang L, Cao J, Tao J, Liang Y. | 03/8/2024 |
| FAM76B regulates PI3K/Akt/NF-kappaB-mediated M1 macrophage polarization by influencing the stability of PIK3CD mRNA. | FAM76B regulates PI3K/Akt/NF-κB-mediated M1 macrophage polarization by influencing the stability of PIK3CD mRNA.
Wang J, Zhao X, Wang Q, Zheng X, Simayi D, Zhao J, Yang P, Mao Q, Xia H., Free PMC Article | 03/1/2024 |
| FOXM1 transcriptional regulation of RacGAP1 activates the PI3K/AKT signaling pathway to promote the proliferation, migration, and invasion of cervical cancer cells. | FOXM1 transcriptional regulation of RacGAP1 activates the PI3K/AKT signaling pathway to promote the proliferation, migration, and invasion of cervical cancer cells.
Yao H, Li J, Zhou D, Pan X, Chu Y, Yin J. | 02/23/2024 |
| Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia. | Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Chang R, Su Y, Kong H, Wang F, Xing Y, Jiang L, Xin H. | 02/23/2024 |
| The novel miR-873-5p-YWHAE-PI3K/AKT axis is involved in non-small cell lung cancer progression and chemoresistance by mediating autophagy. | The novel miR-873-5p-YWHAE-PI3K/AKT axis is involved in non-small cell lung cancer progression and chemoresistance by mediating autophagy.
Li Z, Liu J, Wang P, Zhang B, He G, Yang L. | 02/20/2024 |
| Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway. | Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway.
Liang W, Liu M, Su Y, Wen Y, Wang L, Shan J, Zhao J, Xie K, Wang J. | 02/16/2024 |
| Activated phosphoinositide 3-kinase delta syndrome caused by PIK3CD mutations: expanding the phenotype. | Activated phosphoinositide 3-kinase δ syndrome caused by PIK3CD mutations: expanding the phenotype.
Zhao P, Huang J, Fu H, Xu J, Li T, Zhang X, Meng Q, Zhang L, Tan L, Zhang W, Chen H, Lu X, Ding Y, He X., Free PMC Article | 02/8/2024 |
| IRS1 promotes thyroid cancer metastasis through EMT and PI3K/AKT pathways. | IRS1 promotes thyroid cancer metastasis through EMT and PI3K/AKT pathways.
Yu F, Huang D, Kuang Y, Dong J, Han Q, Zhou J, Teng X. | 02/6/2024 |
| KIRREL promotes the proliferation of gastric cancer cells and angiogenesis through the PI3K/AKT/mTOR pathway. | KIRREL promotes the proliferation of gastric cancer cells and angiogenesis through the PI3K/AKT/mTOR pathway.
Wang T, Chen S, Wang Z, Li S, Fei X, Wang T, Zhang M., Free PMC Article | 01/30/2024 |
| A PI3K gene expression signature predicts for recurrence in early-stage non-small cell lung cancer treated with stereotactic body radiation therapy. | A PI3K gene expression signature predicts for recurrence in early-stage non-small cell lung cancer treated with stereotactic body radiation therapy.
Sebastian NT, Webb A, Shilo K, Robb R, Xu-Welliver M, Haglund K, Brownstein J, DeNicola GM, Shen C, Williams TM. | 12/22/2023 |
| Polymorphisms in PI3K/AKT genes and gene-smoking interaction are associated with susceptibility to tuberculosis. | Polymorphisms in PI3K/AKT genes and gene‑smoking interaction are associated with susceptibility to tuberculosis.
Wu C, Liu H, Lin Y, An R, Wang M, Zhong H, Yi H, Wang Q, Tan H, Chen L, Deng J, Chen M. | 12/22/2023 |
| USP14 Regulates ATF2/PIK3CD Axis to Promote Microvascular Endothelial Cell Proliferation, Migration, and Angiogenesis in Diabetic Retinopathy. | USP14 Regulates ATF2/PIK3CD Axis to Promote Microvascular Endothelial Cell Proliferation, Migration, and Angiogenesis in Diabetic Retinopathy.
He FT, Fu XL, Li MH, Fu CY, Chen JZ. | 11/1/2023 |
| CircCDK1 blocking IGF2BP2-mediated m6A modification of CPPED1 promotes laryngeal squamous cell carcinoma metastasis via the PI3K/AKT signal pathway. | CircCDK1 blocking IGF2BP2-mediated m6A modification of CPPED1 promotes laryngeal squamous cell carcinoma metastasis via the PI3K/AKT signal pathway.
Li J, Cao H, Yang J, Wang B. | 09/13/2023 |
| NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K/AKT signaling pathway through ac4C modification. | NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K/AKT signaling pathway through ac4C modification.
Cui Z, Xu Y, Wu P, Lu Y, Tao Y, Zhou C, Cui R, Li J, Han R. | 09/11/2023 |
| CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity. | CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
Chen J, Lin Y, Zheng S, Chen Q, Tang S, Zhong X., Free PMC Article | 09/8/2023 |
| Mechanisms controlling membrane recruitment and activation of the autoinhibited SHIP1 inositol 5-phosphatase. | Mechanisms controlling membrane recruitment and activation of the autoinhibited SHIP1 inositol 5-phosphatase.
Waddell GL, Drew EE, Rupp HP, Hansen SD., Free PMC Article | 09/6/2023 |
| Knockdown of CENPN Inhibits Glucose Metabolism and Induces G1 Arrest in Esophageal Cancer Cells by Regulating PI3K/AKT Signaling Pathway. | Knockdown of CENPN Inhibits Glucose Metabolism and Induces G1 Arrest in Esophageal Cancer Cells by Regulating PI3K/AKT Signaling Pathway.
Xu S, Wei X. | 08/2/2023 |
| RBFOX2 confers tumor growth by PI3K/AKT and MAPK signaling in gastric cancer. | RBFOX2 confers tumor growth by PI3K/AKT and MAPK signaling in gastric cancer.
Xie S, Li Z, Zhong Y, Fang Q, Ma A, Wang Y, Zeng L, Lin T, Xie D. | 08/2/2023 |
| TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway. | TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
He Y, Zhang B, Han D, Du Y, Zhang X, Wang H, Yue Z, Shang P. | 07/27/2023 |
| MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis. | MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.
Yang Y, Qiu R, Weng Q, Xu Z, Song J, Zhao S, Meng M, Zhang D, Kong C, Wang H, Xu M, Zhao Z, Ji J., Free PMC Article | 07/17/2023 |
| TLR4 inhibited autophagy by modulating PI3K/AKT/mTOR signaling pathway in Gastric cancer cell lines. | TLR4 inhibited autophagy by modulating PI3K/AKT/mTOR signaling pathway in Gastric cancer cell lines.
Zhang Q, Dan J, Meng S, Li Y, Li J. | 06/14/2023 |
| AQP3-Dependent PI3K/Akt Modulation in Breast Cancer Cells. | AQP3-Dependent PI3K/Akt Modulation in Breast Cancer Cells.
Mlinarić M, Lučić I, Milković L, da Silva IV, Tartaro Bujak I, Musani V, Soveral G, Čipak Gašparović A., Free PMC Article | 06/7/2023 |