| Identification and immunological characterization of PLA2G2A and cell death-associated molecular clusters in idiopathic pulmonary fibrosis. | Identification and immunological characterization of PLA2G2A and cell death-associated molecular clusters in idiopathic pulmonary fibrosis.
Lv W, Mao H, Ruan Y, Li S, Shimizu K, Zhang L, Zhang C. | 09/26/2023 |
| [Diagnostic value of lipoprotein-associated phospholipase A2 in OPBR combined with gallbladder cholesterol deposition]. | [Diagnostic value of lipoprotein-associated phospholipase A2 in OPBR combined with gallbladder cholesterol deposition].
Zhang HL, Xiang YK, Hu H, Zhang C, Kong XY, Tian FZ, Da XB, Qiu C, Lyu BN, Wang YB, Yang YL. | 05/3/2023 |
| Secretory Phospholipase A2 and Interleukin-6 Levels as Predictive Markers of the Severity and Outcome of Patients with COVID-19 Infections. | Secretory Phospholipase A2 and Interleukin-6 Levels as Predictive Markers of the Severity and Outcome of Patients with COVID-19 Infections.
Urazov S, Chernov A, Popov O, Klenkova N, Sushentseva N, Polkovnikova I, Apalko S, Kislyuk K, Pavlovich D, Ivanov A, Shcherbak S., Free PMC Article | 03/31/2023 |
| Interplay between C1-inhibitor and group IIA secreted phospholipase A2 impairs their respective function. | Interplay between C1-inhibitor and group IIA secreted phospholipase A(2) impairs their respective function.
Ferrara AL, Bova M, Petraroli A, Marasco D, Payré C, Fortuna S, Palestra F, Ciardi R, Marone G, Spadaro G, Lambeau G, Loffredo S., Free PMC Article | 01/28/2023 |
| PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation. | PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation.
Zhang M, Xiang R, Glorieux C, Huang P., Free PMC Article | 10/22/2022 |
| Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A2s. | Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A(2)s.
Hayashi D, Mouchlis VD, Dennis EA., Free PMC Article | 03/26/2022 |
| Elevated lipoprotein(a) and lipoprotein-associated phospholipase A2 are associated with unfavorable functional outcomes in patients with ischemic stroke. | Elevated lipoprotein(a) and lipoprotein-associated phospholipase A(2) are associated with unfavorable functional outcomes in patients with ischemic stroke.
Jiang X, Xu J, Hao X, Xue J, Li K, Jin A, Lin J, Meng X, Zheng L, Wang Y., Free PMC Article | 03/26/2022 |
| Secretory Phospholipase A2 Digital Expression Analysis in Colon Adenocarcinoma. | Secretory Phospholipase A2 Digital Expression Analysis in Colon Adenocarcinoma.
Falidas E, Kitsiouli E, Spyropoulou D, Tsiambas E, Kalogirou A, Tsouvelas G, Papadopoulos S, Mitsis M, Lekka M, Mastronikoli S, Peschos D, Dimas O, Vlachos K., Free PMC Article | 03/12/2022 |
| A novel prognosis prediction model, including cytotoxic T lymphocyte-associated antigen-4, ischemia-modified albumin, lipoprotein-associated phospholipase A2, glial fibrillary acidic protein, and homocysteine, for ischemic stroke in the Chinese hypertensive population. | A novel prognosis prediction model, including cytotoxic T lymphocyte-associated antigen-4, ischemia-modified albumin, lipoprotein-associated phospholipase A2, glial fibrillary acidic protein, and homocysteine, for ischemic stroke in the Chinese hypertensive population.
Ma J, Shen L, Bao L, Yuan H, Wang Y, Liu H, Wang Q., Free PMC Article | 11/27/2021 |
| Association between serum secretory phospholipase A2 and risk of ischaemic stroke. | Association between serum secretory phospholipase A2 and risk of ischaemic stroke.
Smith JW, Barlas RS, Mamas MA, Boekholdt SM, Mallat Z, Luben RN, Wareham NJ, Khaw KT, Myint PK. | 10/30/2021 |
| Expression of Secretory Phospholipase A2 Group IIa in Breast Cancer and Correlation to Prognosis in a Cohort of Advanced Breast Cancer Patients. | Expression of Secretory Phospholipase A2 Group IIa in Breast Cancer and Correlation to Prognosis in a Cohort of Advanced Breast Cancer Patients.
Jespersen SS, Stovgaard ES, Nielsen D, Christensen TD, Buhl ASK, Christensen IJ, Balslev E. | 10/16/2021 |
| Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality. | Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality.
Snider JM, You JK, Wang X, Snider AJ, Hallmark B, Zec MM, Seeds MC, Sergeant S, Johnstone L, Wang Q, Sprissler R, Carr TF, Lutrick K, Parthasarathy S, Bime C, Zhang HH, Luberto C, Kew RR, Hannun YA, Guerra S, McCall CE, Yao G, Del Poeta M, Chilton FH., Free PMC Article | 10/16/2021 |
| Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model. | Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model.
Dacheux M, Chaouch S, Joy A, Labat A, Payré C, Petit-Paitel A, Bihl F, Lagrange I, Grellier P, Touqui L, Lambeau G, Deregnaucourt C. | 10/2/2021 |
| Clinical Significance of PLA2G2A Expression in Gastric Cancer Patients who Receive Gastrectomy and Adjuvant S-1. | Clinical Significance of PLA2G2A Expression in Gastric Cancer Patients who Receive Gastrectomy and Adjuvant S-1.
Hatori S, Sakamaki K, Yokohori T, Kimura Y, Hiroshima Y, Hashimoto I, Komori K, Watanabe H, Kano K, Fujikawa H, Aoyama T, Numata M, Yamada T, Tamagawa H, Yamamoto N, Ogata T, Shizawa M, Yukawa N, Morinaga S, Rino Y, Masuda M, Saeki H, Miyagi Y, Oshima T. | 07/10/2021 |
| Structural aspects and activation mechanism of human secretory group IIA phospholipase. | Structural aspects and activation mechanism of human secretory group IIA phospholipase.
Manukyan AK. | 06/19/2021 |
| Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A2. | Structural and Functional Aspects of Targeting the Secreted Human Group IIA Phospholipase A(2).
Kim RR, Chen Z, Mann TJ, Bastard K, F Scott K, Church WB., Free PMC Article | 03/20/2021 |
| Surfactant-secreted phospholipase A2 interplay and respiratory outcome in preterm neonates. | Surfactant-secreted phospholipase A(2) interplay and respiratory outcome in preterm neonates.
De Luca D, Shankar-Aguilera S, Autilio C, Raschetti R, Vedovelli L, Fitting C, Payré C, Jeammet L, Perez-Gil J, Cogo PE, Carnielli VP, Lambeau G, Touqui L. | 10/10/2020 |
| Individuals with heterozygous PLA2G2A rs11573156 CG genotype was found to have significantly reduced risk of prostate cancer (PCa) metastasis compared to the carriers of homozygous CC genotype suggesting an anti-metastatic effect for the G allele. No association was found between PCa susceptibility and Gleason score with PLA2G2A rs11573156 in Turkish population. | Association of 5'UTR polymorphism of secretory phospholipase A2 group IIA (PLA2G2A) gene with prostate cancer metastasis.
Ozturk K, Onal MS, Efiloglu O, Nikerel E, Yildirim A, Telci D. | 06/6/2020 |
| A significant correlation exists between -763C > G sPLA2G2A gene polymorphisms and the disease incidence in patients with T2DM. sPLA2 serum level is significantly higher in patients with T2DM disease. | Polymorphism of Secretary PLA2G2A Gene Associated with Its Serum Level in Type2 Diabetes Mellitus Patients in Northern Iran.
Khajeniazi S, Marjani A, Shakeri R, Hakimi S. | 04/25/2020 |
| Our results suggest IDO1 expression levels are epigenetically regulated by DNA methylation. This study provides rationale to test IDO1 methylation as potential biomarker for prediction of response to IDO1 immune checkpoint inhibitors in HNSCC. | Context-dependent effect of sPLA(2)-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer.
Chovatiya GL, Sunkara RR, Roy S, Godbole SR, Waghmare SK., Free PMC Article | 03/21/2020 |
| The combination of carotid artery color Doppler ultrasonography with the Lp-PLA2 and Cys C plasma levels is of great clinical value in the diagnosis and treatment of arteriosclerotic cerebral infarction. | Carotid artery color Doppler ultrasonography and plasma levels of lipoprotein-associated phospholipase A2 and cystatin C in arteriosclerotic cerebral infarction.
Huang L, Yao S., Free PMC Article | 03/21/2020 |
| SAA and sPLA2 can act synergistically to remove cellular membrane debris from injured sites, which is a prerequisite for tissue healing. | Synergy between serum amyloid A and secretory phospholipase A(2).
Jayaraman S, Fändrich M, Gursky O., Free PMC Article | 02/29/2020 |
| Elevated Lp-PLA2 activity in non-severe asthmatics suggests increased atherosclerotic risk in this group. Lower Lp-PLA2 activity accompanied by its inverse relationship to inflammatory or prothrombotic blood biomarkers observed in turn in severe asthmatics might be related to the pathogenesis of more severe asthma phenotype. | Increased activity of lipoprotein-associated phospholipase A(2) in non-severe asthma.
Kuczia P, Mastalerz L, Potaczek DP, Cybulska A, Zareba L, Bazan-Socha S, Undas A. | 02/15/2020 |
| lncRNA SLNCR1 and secretory sPLA2 were both upregulated in NSCLC. lncRNA SLNCR1 may regulate cancer cell migration, invasion and stemness in NSCLC through interactions with secretory sPLA2. | Long non‑coding RNA SLNCR1 regulates non‑small cell lung cancer migration, invasion and stemness through interactions with secretory phospholipase A2.
Xu W, Xu Q, Kuang D, Wang Z, Lu Q, Lin Q, Wu H, Chen L., Free PMC Article | 02/8/2020 |
| sPLA2 IIa inhibition attenuates the potent effects of PGE2-induced invasiveness. This is mediated by decreasing pro-inflammatory and invasion-promoting ICAM-1via the STAT-3 pathway. These data further describe how sPLA2 IIa inhibition mechanistically exerts its anticancer effects and support its use as an antineoplastic agent. | Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma.
Halpern AL, Kohtz PD, Rove JY, Ao L, Meng X, Fullerton DA, Weyant MJ. | 05/18/2019 |