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    PANK1 pantothenate kinase 1 [ Homo sapiens (human) ]

    Gene ID: 53354, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression and Prognostic Role of PANK1 in Glioma.

    Expression and Prognostic Role of PANK1 in Glioma.
    Zhao Z, Xu X, Ma S, Li L., Free PMC Article

    05/22/2024
    Pantothenate Kinase 1 Inhibits the Progression of Hepatocellular Carcinoma by Negatively Regulating Wnt/beta-catenin Signaling.

    Pantothenate Kinase 1 Inhibits the Progression of Hepatocellular Carcinoma by Negatively Regulating Wnt/β-catenin Signaling.
    Zi Y, Gao J, Wang C, Guan Y, Li L, Ren X, Zhu L, Mu Y, Chen SH, Zeng Z, Cao Z, Rong Z, Chen P, Zhang X, Chen T, Xin H, Li X, Li Z, Sun L, Deng Y, Li N, Nie Y., Free PMC Article

    04/23/2022
    p53 plays an important role in regulating energy homeostasis through transcriptional control of PANK1.

    p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene.
    Wang SJ, Yu G, Jiang L, Li T, Lin Q, Tang Y, Gu W., Free PMC Article

    08/31/2013
    PANK deficiency leads to abnormalities in F-actin organization.

    Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism.
    Siudeja K, Grzeschik NA, Rana A, de Jong J, Sibon OC., Free PMC Article

    05/4/2013
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

    Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
    Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, Zaitlen NA, Varilo T, Kaakinen M, Sovio U, Ruokonen A, Laitinen J, Jakkula E, Coin L, Hoggart C, Collins A, Turunen H, Gabriel S, Elliot P, McCarthy MI, Daly MJ, Järvelin MR, Freimer NB, Peltonen L., Free PMC Article

    12/2/2009
    Observational study of gene-disease association. (HuGE Navigator)

    A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
    Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article

    12/2/2009
    analysis of the homodimeric structures of the catalytic cores of PanK1alpha and PanK3 in complex with acetyl-CoA and the the structural effects of the PanK2 mutations that have been implicated in neurodegeneration

    Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
    Hong BS, Senisterra G, Rabeh WM, Vedadi M, Leonardi R, Zhang YM, Rock CO, Jackowski S, Park HW.

    01/21/2010
    alternative splicing product

    In reference to the Short Communication published by Ni et al.
    Westaway SK, Hayflick SJ, Zhou B, Gitschier JD.

    01/21/2010
    PPARalpha transcription factor as a major factor governing hepatic CoA levels by specific modulation of PANK1alpha gene expression

    PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression.
    Ramaswamy G, Karim MA, Murti KG, Jackowski S.

    01/21/2010
    molecular cloning and characterization of a new human PanK gene

    Cloning and characterization of a novel human pantothenate kinase gene.
    Ni X, Ma Y, Cheng H, Jiang M, Ying K, Xie Y, Mao Y.

    01/21/2010
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