| Exhaled phospholipid transfer protein and hepatocyte growth factor receptor in lung adenocarcinoma. | Exhaled phospholipid transfer protein and hepatocyte growth factor receptor in lung adenocarcinoma.
Andreasson J, Bodén E, Fakhro M, von Wachter C, Olm F, Malmsjö M, Hallgren O, Lindstedt S., Free PMC Article | 01/28/2023 |
| PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis. | PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis.
Gnanapradeepan K, Indeglia A, Stieg DC, Clarke N, Shao C, Dougherty JF, Murali N, Murphy ME., Free PMC Article | 01/11/2023 |
| AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning. | AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning.
Jiang C, Jiang W. | 04/23/2022 |
| Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations. | Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations.
Zhang FH, Yin RX, Yao LM, Lin WX, Wu JZ, Yang DZ., Free PMC Article | 01/22/2022 |
| Identification of three predictors of gastric cancer progression and prognosis. | Identification of three predictors of gastric cancer progression and prognosis.
Huang K, Chen S, Xie R, Jiang P, Yu C, Fang J, Liu X, Yu F., Free PMC Article | 11/6/2021 |
| Lipocalin-1 is the acceptor protein for phospholipid transfer protein in tears. | Lipocalin-1 is the acceptor protein for phospholipid transfer protein in tears.
Glasgow BJ, Abduragimov AR., Free PMC Article | 09/11/2021 |
| The selected compounds were further confirmed to target PLTP both biochemically and biophysically and were shown to inhibit apoB secretion from hepatic cells with no apparent toxicity. | Identification of Novel Phospholipid Transfer Protein Inhibitors by High-Throughput Screening.
Hantani R, Takahashi Y, Sotani T, Hantani Y. | 04/18/2020 |
| AAT protects PLTP from proteolytic cleavage and both AAT and PLTP mediate degranulation, possibly via Hck tyrosine kinase inhibition. Deficiency of AAT could contribute to reduced lung PLTP activity and elevated neutrophil signaling associated with lung disease. | Phospholipid transfer protein and alpha-1 antitrypsin regulate Hck kinase activity during neutrophil degranulation.
Ochieng P, Nath S, Macarulay R, Eden E, Dabo A, Campos M, Jiang XC, Foronjy RF, Geraghty P., Free PMC Article | 12/14/2019 |
| Profurin can interact with intracellular PLTP and promote its ubiquitination and proteasomal degradation, resulting in less PLTP secretion from the hepatocytes. Furin does not cleave PLTP; instead, it forms a complex with PLTP, likely through its prodomain | Prodomain of Furin Promotes Phospholipid Transfer Protein Proteasomal Degradation in Hepatocytes.
Yu Y, Lei X, Jiang H, Li Z, Creemers JWM, Zhang M, Qin S, Jin W, Jiang XC., Free PMC Article | 11/2/2019 |
| REVIEW: the major progress made in the PLTP research field and emphasis on its impact on lipoprotein metabolism and atherosclerosis, as well as its regulation | Phospholipid transfer protein: its impact on lipoprotein homeostasis and atherosclerosis.
Jiang XC., Free PMC Article | 06/29/2019 |
| PLTP promotes platelet aggregation and is involved in hyper-coagulation | Plasma Phospholipid Transfer Protein Promotes Platelet Aggregation.
Zhao XM, Wang Y, Yu Y, Jiang H, Babinska A, Chen XY, He KG, Min XD, Han JJ, Yang CX, Deng K, Xue J, Zhang X, Song GH, Qin SC, Jiang XC., Free PMC Article | 02/2/2019 |
| Plasma PLTP activity was higher in patients with NAFLD. | Plasma lecithin:cholesterol acyltransferase and phospholipid transfer protein activity independently associate with nonalcoholic fatty liver disease.
Nass KJ, van den Berg EH, Gruppen EG, Dullaart RPF. | 02/2/2019 |
| Study demonstrated that PLTP is overexpressed in synovial tissue of patients with chronic inflammatory rheumatisms, such as rheumatoid arthritis (RA), when compared to osteoarthritis patients (OA); and that RA but not OA patients displayed elevated levels of PLTP activity in synovial fluid, which were correlated with pro-inflammatory cytokine levels. | PhosphoLipid transfer protein (PLTP) exerts a direct pro-inflammatory effect on rheumatoid arthritis (RA) fibroblasts-like-synoviocytes (FLS) independently of its lipid transfer activity.
Audo R, Deckert V, Daien CI, Che H, Elhmioui J, Lemaire S, Pais de Barros JP, Desrumaux C, Combe B, Hahne M, Lagrost L, Morel J., Free PMC Article | 06/30/2018 |
| These results indicate that PLTP and MASP-1 can serve as plasma biomarkers for the early diagnosis and treatment of Age-related macular degeneration , which is critical for preventing Age-related macular degeneration -related blindness. | Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration.
Kim HJ, Ahn SJ, Woo SJ, Hong HK, Suh EJ, Ahn J, Park JH, Ryoo NK, Lee JE, Kim KW, Park KH, Lee C., Free PMC Article | 05/19/2018 |
| PLTP activity did not affect this metric. Thus, deviations in PLTP activity from the wild-type level reduce HDL mass and ex vivo cholesterol efflux capacity, but not the rate of macrophage cholesterol efflux to plasma or in vivo mRCT. | Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport.
Kuwano T, Bi X, Cipollari E, Yasuda T, Lagor WR, Szapary HJ, Tohyama J, Millar JS, Billheimer JT, Lyssenko NN, Rader DJ., Free PMC Article | 09/9/2017 |
| serum CETP and PLTP activity in patients diagnosed with hypothyroidism, was examined. | Serum Lipid Transfer Proteins in Hypothyreotic Patients Are Inversely Correlated with Thyroid-Stimulating Hormone (TSH) Levels.
Skoczyńska A, Wojakowska A, Turczyn B, Zatońska K, Wołyniec M, Rogala N, Szuba A, Bednarek-Tupikowska G., Free PMC Article | 04/29/2017 |
| PLTP may regulate cigarette smoke extract-induced IL-8 expression via the ERK1/2 signaling pathway in human pulmonary epithelial cells | Effect of Phospholipid Transfer Protein on Cigarette Smoke Extract-Induced IL-8 Production in Human Pulmonary Epithelial Cells.
Li Y, Yu X, Fu X, Wu F, Zou L, Chen Y, Chen Y. | 04/8/2017 |
| LPL and PLTP appear to be novel glioma-associated proteins and play a role in the progression of human glioma | Lipoprotein lipase and phospholipid transfer protein overexpression in human glioma cells and their effect on cell growth, apoptosis, and migration.
Dong W, Gong H, Zhang G, Vuletic S, Albers J, Zhang J, Liang H, Sui Y, Zheng J. | 02/4/2017 |
| association of PON-1 activity with PLTP activity was lost in analysis which included large HDL particles | Paraoxonase-1 activity is positively related to phospholipid transfer protein activity in type 2 diabetes mellitus: Role of large HDL particles.
Dullaart RPF, Gruppen EG, Dallinga-Thie GM. | 12/17/2016 |
| a novel association between PLTPa and PON1 activity | PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity.
Kim DS, Burt AA, Ranchalis JE, Vuletic S, Vaisar T, Li WF, Rosenthal EA, Dong W, Eintracht JF, Motulsky AG, Brunzell JD, Albers JJ, Furlong CE, Jarvik GP., Free PMC Article | 03/26/2016 |
| The domain of apolipoprotein E4 required for PLTP activation resides within its amino-terminal 1-185 region. | Influence of Isoforms and Carboxyl-Terminal Truncations on the Capacity of Apolipoprotein E To Associate with and Activate Phospholipid Transfer Protein.
Dafnis I, Metso J, Zannis VI, Jauhiainen M, Chroni A. | 01/16/2016 |
| Elevated baseline plasma levels of PLTP are associated with an increased risk of long-term all-cause mortality in patients with diabetes and known or suspected coronary disease. | Elevated baseline plasma phospholipid protein (PLTP) levels are an independent predictor of long-term all-cause mortality in patients with diabetes mellitus and known or suspected coronary artery disease.
Cavusoglu E, Marmur JD, Chhabra S, Hojjati MR, Yanamadala S, Chopra V, Eng C, Jiang XC., Free PMC Article | 12/19/2015 |
| This review summarizes the recent progresses made in the PLTP research field and focuses on the complexity of the implication of PLTP in obesity, insulin resistance and type 2 diabetes mellitus. [review] | Phospholipid transfer protein in diabetes, metabolic syndrome and obesity.
Qin S, Song G, Yu Y. | 10/24/2015 |
| Elevated plasma PLTP activity may predict an increased risk of T2DM in men | Phospholipid transfer protein activity and incident type 2 diabetes mellitus.
Abbasi A, Dallinga-Thie GM, Dullaart RP. | 08/29/2015 |
| High systemic PLTP expression does not contribute significantly to a renal phenotype despite being implicated in systemic atherosclerosis in ApoE deficient mice. | No renal phenotype in human phospholipid transfer protein transgenic apolipoprotein E deficient mice despite severe aortic atherosclerosis.
Dullaart RP, Van Haperen R, Van Den Born J, Van Goor H, De Crom R, Van Tol A. | 03/21/2015 |