Spondyloenchondrodysplasia with immune dysregulation related to ACP5. A report of 4 cases. | Spondyloenchondrodysplasia with immune dysregulation related to ACP5. A report of 4 cases. Dri J, Dos Santos E, Pereyra M, Guillamondegui MJ, Ballester C, Tolin A, Gatica C. | 01/6/2024 |
Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12-month, randomized, double-blind, placebo-controlled trial. | Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12-month, randomized, double-blind, placebo-controlled trial. Matsuzaki K, Hossain S, Wakatsuki H, Tanabe Y, Ohno M, Kato S, Shido O, Hashimoto M. | 06/13/2023 |
Spondyloenchondrodysplasia in five new patients: identification of three novel ACP5 variants with variable neurological presentations. | Spondyloenchondrodysplasia in five new patients: identification of three novel ACP5 variants with variable neurological presentations. Elhossini RM, Elbendary HM, Rafat K, Ghorab RM, Abdel-Hamid MS., Free PMC Article | 05/1/2023 |
The clinical utility of TRACP-5b to monitor anti-resorptive treatments of osteoporosis. | The clinical utility of TRACP-5b to monitor anti-resorptive treatments of osteoporosis. Gossiel F, Ugur A, Peel NFA, Walsh JS, Eastell R. | 05/21/2022 |
Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating beta-catenin signaling. | Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating β-catenin signaling. Hu Y, Wang Q, Yu J, Zhou Q, Deng Y, Liu J, Zhang L, Xu Y, Xiong W, Wang Y., Free PMC Article | 01/29/2022 |
microRNA-877 contributes to decreased non-small cell lung cancer cell growth via the PI3K/AKT pathway by targeting tartrate resistant acid phosphatase 5 activity. | microRNA-877 contributes to decreased non-small cell lung cancer cell growth via the PI3K/AKT pathway by targeting tartrate resistant acid phosphatase 5 activity. Bai X, He C, Fu B, Kong X, Bu J, Zhu K, Zheng W, Zhou F, Ni B., Free PMC Article | 11/27/2021 |
Expression of tartrate-resistant acid phosphatase and cathepsin K during osteoclast differentiation in developing mouse mandibles. | Expression of tartrate-resistant acid phosphatase and cathepsin K during osteoclast differentiation in developing mouse mandibles. Nakamura M, Aoyama N, Yamaguchi S, Sasano Y. | 11/6/2021 |
Intensive weight gain therapy in patients with anorexia nervosa results in improved serum tartrate-resistant acid phosphatase (TRAP) 5a and 5b isoform protein levels. | Intensive weight gain therapy in patients with anorexia nervosa results in improved serum tartrate-resistant acid phosphatase (TRAP) 5a and 5b isoform protein levels. Patlaka C, Tubic B, Lång P, Paulie S, Swolin-Eide D, Magnusson P, Andersson G., Free PMC Article | 07/17/2021 |
MMP-8, TRAP-5, and OPG Levels in GCF Diagnostic Potential to Discriminate between Healthy Patients', Mild and Severe Periodontitis Sites. | MMP-8, TRAP-5, and OPG Levels in GCF Diagnostic Potential to Discriminate between Healthy Patients', Mild and Severe Periodontitis Sites. Hernández M, Baeza M, Contreras J, Sorsa T, Tervahartiala T, Valdés M, Chaparro A, Hernández-Ríos P., Free PMC Article | 06/26/2021 |
A Novel Sandwich ELISA for Tartrate-Resistant Acid Phosphatase 5a and 5b Protein Reveals that Both Isoforms are Secreted by Differentiating Osteoclasts and Correlate to the Type I Collagen Degradation Marker CTX-I In Vivo and In Vitro. | A Novel Sandwich ELISA for Tartrate-Resistant Acid Phosphatase 5a and 5b Protein Reveals that Both Isoforms are Secreted by Differentiating Osteoclasts and Correlate to the Type I Collagen Degradation Marker CTX-I In Vivo and In Vitro. Mira-Pascual L, Patlaka C, Desai S, Paulie S, Näreoja T, Lång P, Andersson G. | 06/12/2021 |
Postoperative expressions of TRACP5b and CA125 in patients with breast cancer and their values for monitoring bone metastasis. | Postoperative expressions of TRACP5b and CA125 in patients with breast cancer and their values for monitoring bone metastasis. Feng C, Zhan Y, Shao H, Wang Z, Zhu S. | 01/23/2021 |
Altered levels of BMD, PRL, BAP and TRACP-5b in male chronic patients with schizophrenia. | Altered levels of BMD, PRL, BAP and TRACP-5b in male chronic patients with schizophrenia. Du X, Ye F, Li J, Zhao Y, Xiao W, Tang X, Zhang X., Free PMC Article | 01/16/2021 |
Runt-related transcription factor 1 contributes to lung cancer development by binding to tartrate-resistant acid phosphatase 5. | Runt-related transcription factor 1 contributes to lung cancer development by binding to tartrate-resistant acid phosphatase 5. He C, Bai X, Li Y, Sun H, Kong X, Fu B, Chen L, Zhu K, Li P, Xu S., Free PMC Article | 09/19/2020 |
Multiple regression analysis showed that a higher log (TRACP-5b) was correlated with a lower stiffness index (p = 0.014) and log (BAP[alkaline phosphatase, biomineralization associated]) was not correlated with stiffness index after adjusting for covariates (p = 0.136). | Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in post-menopausal Japanese women. Nishimura T, Arima K, Abe Y, Kanagae M, Mizukami S, Okabe T, Tomita Y, Goto H, Hasegawa M, Sou Y, Horiguchi I, Aoyagi K. | 02/8/2020 |
serum level of TRACP5b may be used as a sensitive indicator of bone tumors | Diagnostic value of TRACP5b expression in patients with bone tumors. Zhang Q, Cao L, Miao XD, Wu YP. | 06/22/2019 |
high expression of ACP5 correlates with tumor progression and may serve as a potential prognostic biomarker in lung AD. | Prognostic significance of ACP5 expression in patients with lung adenocarcinoma. Gao YL, Liu MR, Yang SX, Dong YJ, Tan XF. | 10/6/2018 |
TRACP-5b level is significantly associated with the OPG level and with the severity and extent of coronary atherosclerosis in coronary artery disease patients | Serum Tartrate-resistant Acid Phosphatase-5b Levels are Associated with the Severity and Extent of Coronary Atherosclerosis in Patients with Coronary Artery Disease. Morisawa T, Nakagomi A, Kohashi K, Kusama Y, Shimizu W., Free PMC Article | 07/14/2018 |
Adipokine tartrate-resistant acid phosphatase 5a (TRAP 5a) serum levels correlated positively to anthropometric obesity parameters but not to metabolic syndrome risk factors, indicating that serum TRAP 5a is associated with pathological adipose tissue expansion. | The adipokine tartrate-resistant acid phosphatase 5a in serum correlates to adipose tissue expansion in obesity. Patlaka C, Mira Pascual L, Paulie S, Henriksson AF, Arner P, Lång P, Andersson G. | 06/30/2018 |
TRAP promotes metastasis-related cell properties in MDA-MB-231 breast cancer cells via TGFbeta2/TbetaR and CD44, thereby identifying a potential signaling mechanism associated to TRAP action in breast cancer cells. | Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells. Reithmeier A, Panizza E, Krumpel M, Orre LM, Branca RMM, Lehtiö J, Ek-Rylander B, Andersson G., Free PMC Article | 05/26/2018 |
Serum TRAcP5b activity was associated with density of TRAcP-positive osteoclasts in the subchondral bone of medial tibia plateaux. TRAcP-positive osteoclasts were more abundant in people with symptomatic knee osteoarthritis compared to controls. Serum TRAcP5b activity was associated with baseline pain and pain change. | Pain prediction by serum biomarkers of bone turnover in people with knee osteoarthritis: an observational study of TRAcP5b and cathepsin K in OA. Nwosu LN, Allen M, Wyatt L, Huebner JL, Chapman V, Walsh DA, Kraus VB. | 03/24/2018 |
Although serum procollagen type-1 N-terminal propeptide (PINP) levels were not found to be different, tartrate-resistant acid phosphatase type 5b isoform (TRACP 5b) levels were significantly higher in the control group. | Congenital Hypothyroidism and Bone Remodeling Cycle. Karakaş NM, Tulgar Kınık S, Özdemir B, Muratoğlu Şahin N, Tekindal MA, Haberal A., Free PMC Article | 03/24/2018 |
Nidogen-2, a protein shown to be expressed intracellularly and for secretion by pre-adipocytes, was shown to interact, through its globular G3 domain, with TRAP 5a in vitro. | The growth factor-like adipokine tartrate-resistant acid phosphatase 5a interacts with the rod G3 domain of adipocyte-produced nidogen-2. Patlaka C, Mai HA, Lång P, Andersson G. | 09/23/2017 |
Tartrate-resistant acid phosphatase deficiency in plasmacytoid dendritic cells leads to increased IFNalpha production, providing at least a partial explanation for how ACP5 mutations cause lupus in the context of spondyloenchondrodysplasia. Detection of ACP5 missense variants in a lupus cohort suggests that impaired tartrate-resistant acid phosphatase functioning may increase susceptibility to sporadic lupus | Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus. An J, Briggs TA, Dumax-Vorzet A, Alarcón-Riquelme ME, Belot A, Beresford M, Bruce IN, Carvalho C, Chaperot L, Frostegård J, Plumas J, Rice GI, Vyse TJ, Wiedeman A, Crow YJ, Elkon KB. | 07/8/2017 |
Biallelic ACP5 mutations are associated with autoimmune cytopenias. | Childhood-onset autoimmune cytopenia as the presenting feature of biallelic ACP5 mutations. Sacri AS, Bruwier A, Baujat G, Breton S, Blanche S, Briggs TA, Bader-Meunier B. | 06/24/2017 |
Severe short stature can be the only presenting sign of ACP5 deficiency and the latter could therefore be considered as a rare cause in the differential diagnosis of severe, proportionate growth failure. | Severe Short Stature in Two Siblings as the Presenting Sign of ACP5 Deficiency. de Bruin C, Orbak Z, Andrew M, Hwa V, Dauber A., Free PMC Article | 04/8/2017 |