| 14-3-3beta isoform is specifically acetylated at Lys51 during differentiation to the osteogenic lineage. | 14-3-3β isoform is specifically acetylated at Lys51 during differentiation to the osteogenic lineage.
Frontini-López YR, Gojanovich AD, Del Veliz S, Uhart M, Bustos DM. | 03/19/2022 |
| The 14-3-3 protein YWHAB inhibits glucagon-induced hepatic gluconeogenesis through interacting with the glucagon receptor and FOXO1. | The 14-3-3 protein YWHAB inhibits glucagon-induced hepatic gluconeogenesis through interacting with the glucagon receptor and FOXO1.
Ji L, Wang Q, Liu M, Zhu C, Xiao Y, Han J, Fang Y, Ye J, Yin J, Wei L. | 07/24/2021 |
| 14-3-3 proteins beta and gamma can potentially be used as a cerebrospinal fluid marker of neuronal damage in parasitic eosinophilic meningitis caused by A | Increased 14-3-3β and γ protein isoform expressions in parasitic eosinophilic meningitis caused by Angiostrongylus cantonensis infection in mice.
Tsai HC, Chen YH, Yen CM, Lee SS, Chen YS., Free PMC Article | 12/7/2019 |
| Data indicate 14-3-3 beta protein as an interacting partner of type 1 cannabinoid receptor (CB1R). | Cannabinoid receptor activation inhibits cell cycle progression by modulating 14-3-3β.
Jung HW, Park I, Ghil S., Free PMC Article | 06/27/2015 |
| SelW enhances myoblast differentiation by inhibiting TAZ binding to 14-3-3. | Selenoprotein W enhances skeletal muscle differentiation by inhibiting TAZ binding to 14-3-3 protein.
Jeon YH, Park YH, Lee JH, Hong JH, Kim IY. | 07/5/2014 |
| the novel protein interaction mode in the 14-3-3beta.ChREBP alpha2 complex. | Structural characterization of a unique interface between carbohydrate response element-binding protein (ChREBP) and 14-3-3β protein.
Ge Q, Huang N, Wynn RM, Li Y, Du X, Miller B, Zhang H, Uyeda K., Free PMC Article | 02/16/2013 |
| Studies suggest that insulin may modulate the cellular function of lipin-1 by regulating its subcellular localization through interactions with 14-3-3 proteins. | Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
Péterfy M, Harris TE, Fujita N, Reue K., Free PMC Article | 04/12/2010 |
| Akt1 is necessary for the growth factor stimulated activation of 14-3-3beta-Rac1-p21 activated kinase (Pak) pathway in endothelial cells and fibroblasts. | 14-3-3beta-Rac1-p21 activated kinase signaling regulates Akt1-mediated cytoskeletal organization, lamellipodia formation and fibronectin matrix assembly.
Somanath PR, Byzova TV., Free PMC Article | 01/21/2010 |
| aldosterone-induced 14-3-3 isoforms, beta and epsilon, interact with phospho-Nedd4-2 as an obligatory heterodimer, blocking its interaction with ENaC and thereby increasing apical ENaC density and sodium transport. | An obligatory heterodimer of 14-3-3beta and 14-3-3epsilon is required for aldosterone regulation of the epithelial sodium channel.
Liang X, Butterworth MB, Peters KW, Walker WH, Frizzell RA., Free PMC Article | 01/21/2010 |
| FBI1 and 14-3-3beta were presented on the MKP-1 promoter. These results indicate that FBI1 promotes sustained ERK1/2 activation through repression of MKP-1 transcription, resulting in promotion of tumorigenicity and metastasis. | A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasis.
Komiya Y, Kurabe N, Katagiri K, Ogawa M, Sugiyama A, Kawasaki Y, Tashiro F. | 01/21/2010 |
| Cbl-b deficiency. Cbl-b deficiency resulted in increased phosphorylation of T758 in the beta2-chain of LFA-1 and thereby in enhanced association of 14-3-3beta protein with the beta2-chain | Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins.
Choi EY, Orlova VV, Fagerholm SC, Nurmi SM, Zhang L, Ballantyne CM, Gahmberg CG, Chavakis T., Free PMC Article | 01/21/2010 |
| 14-3-3 participates in the intracellular trafficking of IRS-1 | 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
Xiang X, Yuan M, Song Y, Ruderman N, Wen R, Luo Z. | 01/21/2010 |
| 14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity | 14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity.
Cavet ME, Lehoux S, Berk BC. | 01/21/2010 |
| The transcription start site was identified and the polyadenylation signals (AATAAA) were found in exon 2 of the mouse gene. In the 5'-upstream sequence, we found three cis elements including a CRE sequence, a TATA box-like sequence, and a C/EBP element. | Isolation and structure of the mouse 14-3-3 eta chain gene and the distribution of 14-3-3 eta mRNA in the mouse brain.
Toyooka K, Muratake T, Watanabe H, Hayashi S, Ichikawa T, Usui H, Washiyama K, Kumanishi T, Takahashi Y. | 01/21/2010 |
| PRAS40 is a novel substrate of Akt, the phosphorylation of which leads to the binding of this protein to 14-3-3. | Identification of a proline-rich Akt substrate as a 14-3-3 binding partner.
Kovacina KS, Park GY, Bae SS, Guzzetta AW, Schaefer E, Birnbaum MJ, Roth RA. | 01/21/2010 |
| These results indicate for the first time that 14-3-3 protein plays a critical anti-apoptotic role in diabetic myocardium by inhibiting the JNK pathway. | Dominant negative 14-3-3 promotes cardiomyocyte apoptosis in early stage of type I diabetes mellitus through activation of JNK.
Gurusamy N, Watanabe K, Ma M, Zhang S, Muslin AJ, Kodama M, Aizawa Y. | 01/21/2010 |
| 14-3-3beta gene plays a pivotal role in abnormal growth of tumor cells in vitro and in vivo. | Forced expression of antisense 14-3-3beta RNA suppresses tumor cell growth in vitro and in vivo.
Sugiyama A, Miyagi Y, Komiya Y, Kurabe N, Kitanaka C, Kato N, Nagashima Y, Kuchino Y, Tashiro F. | 01/21/2010 |
| aldosterone increases the expression of 14-3-3beta, which interacts with phospho-Nedd4-2 to block its interaction with ENaC, thus enhancing sodium absorption by increasing apical membrane ENaC density | 14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels.
Liang X, Peters KW, Butterworth MB, Frizzell RA. | 01/21/2010 |