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    PPARG peroxisome proliferator activated receptor gamma [ Homo sapiens (human) ]

    Gene ID: 5468, updated on 27-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.

    PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis.
    Geng Q, Xu J, Cao X, Wang Z, Jiao Y, Diao W, Wang X, Wang Z, Zhang M, Zhao L, Yang L, Deng T, Fan B, Xu Y, Jia L, Xiao C.

    06/14/2024
    PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.

    PPARgamma dependent PEX11beta counteracts the suppressive role of SIRT1 on neural differentiation of HESCs.
    Esmaeili M, Nasr-Esfahani MH, Shoaraye Nejati A, Safaeinejad Z, Atefi A, L Megraw T, Ghaedi K., Free PMC Article

    06/13/2024
    Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARgamma.

    Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARγ.
    Cheng WL, Chao SP, Zhao F, Cai HH, Zeng Z, Cao JL, Jin Z, Deng KQ, Hu X, Wang H, Lu Z.

    05/28/2024
    Abscisic acid signaling through LANCL2 and PPARgamma induces activation of p38MAPK resulting in dormancy of prostate cancer metastatic cells.

    Abscisic acid signaling through LANCL2 and PPARγ induces activation of p38MAPK resulting in dormancy of prostate cancer metastatic cells.
    Parajuli KR, Jung Y, Taichman RS., Free PMC Article

    04/22/2024
    Dual function of activated PPARgamma by ligands on tumor growth and immunotherapy.

    Dual function of activated PPARγ by ligands on tumor growth and immunotherapy.
    Chen M, Wang H, Cui Q, Shi J, Hou Y.

    04/18/2024
    Identification of PPARG as key gene to link coronary atherosclerosis disease and rheumatoid arthritis via microarray data analysis.

    Identification of PPARG as key gene to link coronary atherosclerosis disease and rheumatoid arthritis via microarray data analysis.
    Zhang Z, Chen Y, Fu X, Chen L, Wang J, Zheng Q, Zhang S, Zhu X., Free PMC Article

    04/12/2024
    Association of Polymorphic Variants of TCF7L2 and PPARG Genes with Metabolic Markers in Patients with Early Disorders of Carbohydrate Metabolism.

    Association of Polymorphic Variants of TCF7L2 and PPARG Genes with Metabolic Markers in Patients with Early Disorders of Carbohydrate Metabolism.
    Isakova DN, Kolomeichuk SN, Petrova YA, Lyapina MV, Troshina IA, Voronin KA, Petrov IM.

    03/31/2024
    Adipocyte-rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator-activated receptor gamma/ABCG2 in epithelial ovarian cancer.

    Adipocyte‑rich microenvironment promotes chemoresistance via upregulation of peroxisome proliferator‑activated receptor gamma/ABCG2 in epithelial ovarian cancer.
    Chen S, Liu Z, Wu H, Wang B, Ouyang Y, Liu J, Zheng X, Zhang H, Li X, Feng X, Li Y, Shen Y, Zhang H, Xiao B, Yu C, Deng W., Free PMC Article

    03/5/2024
    Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor gamma following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1beta Release.

    Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor γ following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1β Release.
    Arnett E, Wolff J, Leopold Wager CM, Simper J, Badrak JL, Ontiveros CO, Ni B, Schlesinger LS.,

    02/23/2024
    Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARgamma.

    Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ.
    Shibata T, Bhat SA, Cao D, Saito S, Bernstein EA, Nishi E, Medenilla JD, Wang ET, Chan JL, Pisarska MD, Tourtellotte WG, Giani JF, Bernstein KE, Khan Z., Free PMC Article

    02/7/2024
    PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.

    PPARG dysregulation as a potential molecular target in adrenal Cushing's syndrome.
    Vetrivel S, Tamburello M, Oßwald A, Zhang R, Khan A, Jung S, Baker JE, Rainey WE, Nowak E, Altieri B, Detomas M, Watts D, Williams TA, Wielockx B, Beuschlein F, Reincke M, Sbiera S, Riester A., Free PMC Article

    12/20/2023
    Expression analysis of PPAR-related lncRNAs in breast cancer.

    Expression analysis of PPAR-related lncRNAs in breast cancer.
    Ghafouri-Fard S, Nicknam A, Safarzadeh A, Eslami S, Samsami M, Jamali E.

    11/18/2023
    Role of PPAR-related genes in chronic heart failure: evidence from large populations.

    Role of PPAR-related genes in chronic heart failure: evidence from large populations.
    Ke ZP, Tao WQ, Zhao G, Cheng K., Free PMC Article

    11/14/2023
    Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-gamma) expression in colorectal carcinoma: Relation to the available clinicopathological parameters.

    Evaluation of C-X-C chemokine receptor type 4 (CXCR4) and Peroxisome proliferator-activated receptor gamma (PPAR-γ) expression in colorectal carcinoma: Relation to the available clinicopathological parameters.
    Bedeer AE, El-Ghaffar Heabah NA.

    11/6/2023
    Perilipin 2-positive mononuclear phagocytes accumulate in the diabetic retina and promote PPARgamma-dependent vasodegeneration.

    Perilipin 2-positive mononuclear phagocytes accumulate in the diabetic retina and promote PPARγ-dependent vasodegeneration.
    Blot G, Karadayi R, Przegralek L, Sartoris TM, Charles-Messance H, Augustin S, Negrier P, Blond F, Muñiz-Ruvalcaba FP, Rivera-de la Parra D, Vignaud L, Couturier A, Sahel JA, Acar N, Jimenez-Corona A, Delarasse C, Garfias Y, Sennlaub F, Guillonneau X., Free PMC Article

    11/2/2023
    Loss of PPARgamma activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.

    Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity.
    Caruso JA, Wang X, Murrow LM, Rodriguez CI, Chen-Tanyolac C, Vu L, Chen YY, Gascard P, Gartner ZJ, Kerlikowske K, Tlsty TD., Free PMC Article

    11/2/2023
    PPARgamma inhibits small airway remodeling through mediating the polarization homeostasis of alveolar macrophages in COPD.

    PPARγ inhibits small airway remodeling through mediating the polarization homeostasis of alveolar macrophages in COPD.
    He S, Tian R, Zhang X, Yao Q, Chen Q, Liu B, Liao L, Gong Y, Yang H, Wang D.

    11/2/2023
    Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma.

    Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma.
    Slominski AT, Kim TK, Slominski RM, Song Y, Qayyum S, Placha W, Janjetovic Z, Kleszczyński K, Atigadda V, Song Y, Raman C, Elferink CJ, Hobrath JV, Jetten AM, Reiter RJ., Free PMC Article

    11/1/2023
    Association of PCSK1 and PPARG1 Allelic Variants with Obesity and Metabolic Syndrome in Mexican Adults.

    Association of PCSK1 and PPARG1 Allelic Variants with Obesity and Metabolic Syndrome in Mexican Adults.
    Velazquez-Roman J, Angulo-Zamudio UA, Leon-Sicairos N, Flores-Villaseñor H, Benitez-Baez M, Espinoza-Salomón A, Karam-León A, Villamil-Ramírez H, Canizales-Quinteros S, Macías-Kauffer L, Monroy-Higuera J, Acosta-Smith E, Canizalez-Roman A., Free PMC Article

    10/6/2023
    IGF1 and PPARG polymorphisms are associated with reduced estimated glomerular filtration rate in a cohort of children and adolescents with type 1 diabetes.

    IGF1 and PPARG polymorphisms are associated with reduced estimated glomerular filtration rate in a cohort of children and adolescents with type 1 diabetes.
    Zusi C, Rioda M, Maguolo A, Emiliani F, Unali I, Costantini S, Corradi M, Contreas G, Morandi A, Maffeis C., Free PMC Article

    08/25/2023
    The role of peroxisome proliferator-activated receptor gamma in lipid metabolism and inflammation in atherosclerosis.

    The role of peroxisome proliferator-activated receptor γ in lipid metabolism and inflammation in atherosclerosis.
    Yang XF, Shang DJ.

    08/9/2023
    Contribution of gene polymorphisms on 3p25 to salivary gland carcinoma, ameloblastoma, and odontogenic keratocyst in the Chinese Han population.

    Contribution of gene polymorphisms on 3p25 to salivary gland carcinoma, ameloblastoma, and odontogenic keratocyst in the Chinese Han population.
    Zheng X, Jing J, Yuan M, Liu N, Song Y.

    08/9/2023
    Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.

    Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.
    Qin C, Diaz-Gallo LM, Tang B, Wang Y, Nguyen TD, Harder A, Lu Y, Padyukov L, Askling J, Hägg S., Free PMC Article

    08/1/2023
    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARgamma.

    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ.
    Zhong Y, Wang Y, Li X, Qin H, Yan S, Rao C, Fan D, Liu D, Deng F, Miao Y, Yang L, Huang K., Free PMC Article

    08/1/2023
    PPARgamma inhibited tumor immune escape by inducing PD-L1 autophagic degradation.

    PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
    Gou Q, Che S, Chen M, Chen H, Shi J, Hou Y., Free PMC Article

    07/17/2023
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