| NECL2 regulates blood-testis barrier dynamics in mouse testes. | NECL2 regulates blood-testis barrier dynamics in mouse testes.
Fu J, Liu X, Yin B, Shu P, Peng X. | 06/7/2023 |
| Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions. | Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.
de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, Biederer T., Free PMC Article | 02/4/2023 |
| Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1. | Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.
Engelmann C, Schuhmachers P, Zdimerova H, Virdi S, Hauri-Hohl M, Pachlopnik Schmid J, Grundhoff A, Marsh RA, Wong WW, Münz C., Free PMC Article | 10/29/2022 |
| Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium. | Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.
Kasai Y, Gan SP, Funaki T, Ohashi-Kumagai Y, Tominaga M, Shiu SJ, Suzuki D, Matsubara D, Sakamoto T, Sakurai-Yageta M, Ito T, Murakami Y., Free PMC Article | 05/28/2022 |
| Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes. | Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes.
Sona C, Yeh YT, Patsalos A, Halasz L, Yan X, Kononenko NL, Nagy L, Poy MN., Free PMC Article | 04/30/2022 |
| The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11. | The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.
Lafage-Pochitaloff M, Gerby B, Baccini V, Largeaud L, Fregona V, Prade N, Juvin PY, Jamrog L, Bories P, Hébrard S, Lagarde S, Mansat-De Mas V, Dovey OM, Yusa K, Vassiliou GS, Jansen JH, Tekath T, Rombaut D, Ameye G, Barin C, Bidet A, Boudjarane J, Collonge-Rame MA, Gervais C, Ittel A, Lefebvre C, Luquet I, Michaux L, Nadal N, Poirel HA, Radford-Weiss I, Ribourtout B, Richebourg S, Struski S, Terré C, Tigaud I, Penther D, Eclache V, Fontenay M, Broccardo C, Delabesse E., Free PMC Article | 04/9/2022 |
| Expression of cell adhesion molecule 1 in human and murine endometrial glandular cells and its increase during the proliferative phase by estrogen and cell density. | Expression of cell adhesion molecule 1 in human and murine endometrial glandular cells and its increase during the proliferative phase by estrogen and cell density.
Kimura R, Otani T, Shiraishi N, Hagiyama M, Yoneshige A, Wada A, Kajiyama H, Takeuchi F, Mizuguchi N, Morishita K, Ito A. | 09/18/2021 |
| Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity. | Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity.
Kim HR, Park JS, Fatima Y, Kausar M, Park JH, Jun CD., Free PMC Article | 07/31/2021 |
| Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons. | Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons.
Sukhanov N, Vainshtein A, Eshed-Eisenbach Y, Peles E., Free PMC Article | 05/1/2021 |
| CADM1 suppresses c-Src activation by binding with Cbp on membrane lipid rafts and intervenes colon carcinogenesis. | CADM1 suppresses c-Src activation by binding with Cbp on membrane lipid rafts and intervenes colon carcinogenesis.
Tsuboi Y, Oyama M, Kozuka-Hata H, Ito A, Matsubara D, Murakami Y. | 02/13/2021 |
| Comparative expression of cell adhesion molecule1 (CADM1) in the testes of experimental mice and some farm animals. | Comparative expression of cell adhesion molecule1 (CADM1) in the testes of experimental mice and some farm animals.
Gewaily MS, Kassab M, Farrag FA, Almadaly EA, Atta MS, Abd-Elmaksoud A, Wakayama T. | 09/26/2020 |
| Nectin-like molecule 2, a necessary sexual maturation regulator, participates in congenital hypogonadotropic hypogonadism. | Nectin-like molecule 2, a necessary sexual maturation regulator, participates in congenital hypogonadotropic hypogonadism.
Tang R, Liu X, Peng Y, Ju W, Hao W, Peng X, Chen R. | 08/13/2020 |
| alternative splicing can give rise to both shedding-susceptible and shedding-resistant CADM1 (cell adhesion molecule 1) variant proteins. | Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.
Shirakabe K, Omura T, Shibagaki Y, Mihara E, Homma K, Kato Y, Yoshimura A, Murakami Y, Takagi J, Hattori S, Ogawa Y., Free PMC Article | 12/1/2018 |
| SynCAM1, Neuroligin-1B and Neuroligin-2A were overexpressed in newborn neurons in the dentate gyrus of 7- to 9-week-old mice. SynCAM1 increased the morphological maturation of dendritic spines and mossy fiber terminals while Neuroligin-1B increased spine density. In contrast, Neuroligin-2A increased both spine density and size as well as GABAergic innervation and resulted in a drastic increase of neuronal survival. | Synaptic Adhesion Molecules Regulate the Integration of New Granule Neurons in the Postnatal Mouse Hippocampus and their Impact on Spatial Memory.
Krzisch M, Fülling C, Jabinet L, Armida J, Gebara E, Cassé F, Habbas S, Volterra A, Hornung JP, Toni N. | 05/5/2018 |
| NF-kB mediated upregulation of CADM1 was identified as a mechanism of TNFalpha induced migration. | Tumor Necrosis Factor α Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB.
Prisco AR, Hoffmann BR, Kaczorowski CC, McDermott-Roe C, Stodola TJ, Exner EC, Greene AS., Free PMC Article | 12/9/2017 |
| The results of this study demonstrate that the synapse-organizing adhesion molecule SynCAM 1 has pronounced effects on neuronal connectivity in the hippocampal CA3 area. | Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1.
Park KA, Ribic A, Laage Gaupp FM, Coman D, Huang Y, Dulla CG, Hyder F, Biederer T., Free PMC Article | 07/22/2017 |
| Cadm1 is a direct target of NFATc1, which is induced by RANKL through epigenetic modification, and regulates osteoclastic bone resorption in a negative feedback manner. | Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1.
Nakamura S, Koyama T, Izawa N, Nomura S, Fujita T, Omata Y, Minami T, Matsumoto M, Nakamura M, Fujita-Jimbo E, Momoi T, Miyamoto T, Aburatani H, Tanaka S., Free PMC Article | 05/13/2017 |
| Data show that cell adhesion molecule 1 (SynCAM 1) generally prolongs the lifetime of spines. | In vivo imaging demonstrates dendritic spine stabilization by SynCAM 1.
Körber N, Stein V., Free PMC Article | 03/11/2017 |
| This experiments show that the survival rate of adult-generated neurons is increased by overexpressing SynCAM 1 | SynCAM 1 improves survival of adult-born neurons by accelerating synapse maturation.
Doengi M, Krupp AJ, Körber N, Stein V. | 11/19/2016 |
| Our study reveals a novel mechanism of chronic NF-kappaB activation by CADM1 in HTLV-1 infected cells | Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.
Pujari R, Hunte R, Thomas R, van der Weyden L, Rauch D, Ratner L, Nyborg JK, Ramos JC, Takai Y, Shembade N., Free PMC Article | 01/16/2016 |
| Study demonstrates that polysialic acid-SynCAM 1 defines a subpopulation of NG2 cells and identifies the presence of polysialic acid-NRP2 in microglia | Polysialic acid on SynCAM 1 in NG2 cells and on neuropilin-2 in microglia is confined to intracellular pools that are rapidly depleted upon stimulation.
Werneburg S, Mühlenhoff M, Stangel M, Hildebrandt H. | 01/16/2016 |
| CADM1 appeared to sustain gap junctional intercellular communication among alpha-cells via homophilic binding and, based on this action, CADM1 appears to prevent excessive secretion of glucagon from alpha-cells. | Adhesion molecule CADM1 contributes to gap junctional communication among pancreatic islet α-cells and prevents their excessive secretion of glucagon.
Ito A, Ichiyanagi N, Ikeda Y, Hagiyama M, Inoue T, Kimura KB, Sakurai MA, Hamaguchi K, Murakami Y. | 01/31/2015 |
| This study demonistrated that SynCAM 1 in the synaptic organization of the rod visual pathway and provide evidence for novel roles of synaptic adhesion in the structural and functional integrity of ribbon synapses. | Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1.
Ribic A, Liu X, Crair MC, Biederer T., Free PMC Article | 09/13/2014 |
| Necl-2 co-localizes with ErbB4 in hippocampus and and regulates ErbB4 signaling in cultured neurons. | Necl-2/CADM1 interacts with ErbB4 and regulates its activity in GABAergic neurons.
Yamada A, Inoue E, Deguchi-Tawarada M, Matsui C, Togawa A, Nakatani T, Ono Y, Takai Y. | 06/21/2014 |
| TGF-beta1 is a potent cytokine that provides an effective mechanism in controlling Necl-2 expression in the testis via Smad-dependent gene repression and clathrin-mediated endocytosis. | Transforming growth factor-β1 (TGF-β1) regulates cell junction restructuring via Smad-mediated repression and clathrin-mediated endocytosis of nectin-like molecule 2 (Necl-2).
Gao Y, Lui WY., Free PMC Article | 02/22/2014 |