| Exploring the role of TRPM4 in calcium-dependent triggered activity and cardiac arrhythmias. | Exploring the role of TRPM4 in calcium-dependent triggered activity and cardiac arrhythmias.
Pironet A, Vandewiele F, Vennekens R. | 05/9/2024 |
| Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis. | Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Ye F, Liu D, Zhang J. | 01/26/2024 |
| The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis. | The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis.
Hu Y, Cang J, Hiraishi K, Fujita T, Inoue R., Free PMC Article | 08/3/2023 |
| Influence of TRPM4 rs8104571 genotype on intracranial pressure and outcomes in African Americans with traumatic brain injury. | Influence of TRPM4 rs8104571 genotype on intracranial pressure and outcomes in African Americans with traumatic brain injury.
Krocker JD, Cotton ME, Schriner JB, Osborn BK, Talanker MM, Wang YW, Cox CS Jr, Wade CE., Free PMC Article | 04/12/2023 |
| Roles of TRPM4 in immune responses in keratinocytes and identification of a novel TRPM4-activating agent. | Roles of TRPM4 in immune responses in keratinocytes and identification of a novel TRPM4-activating agent.
Otsuka Saito K, Fujita F, Toriyama M, Utami RA, Guo Z, Murakami M, Kato H, Suzuki Y, Okada F, Tominaga M, Ishii KJ. | 03/28/2023 |
| The novel TRPM4 c.448G>T variant is associated with familial conduction disorders, cardiomyopathy, and sudden cardiac death. | The novel TRPM4 c.448G>T variant is associated with familial conduction disorders, cardiomyopathy, and sudden cardiac death.
Kovacs B, Winnik S, Medeiros-Domingo A, Costa S, Fu G, Biskup S, Ruschitzka F, Flammer AJ, Tanner FC, Duru F, Saguner AM., Free PMC Article | 09/3/2022 |
| A Novel Role of the TRPM4 Ion Channel in Exocytosis. | A Novel Role of the TRPM4 Ion Channel in Exocytosis.
Stokłosa P, Kappel S, Peinelt C., Free PMC Article | 06/18/2022 |
| Variants in genes encoding the SUR1-TRPM4 non-selective cation channel and sudden infant death syndrome (SIDS): potentially increased risk for cerebral edema. | Variants in genes encoding the SUR1-TRPM4 non-selective cation channel and sudden infant death syndrome (SIDS): potentially increased risk for cerebral edema.
Qu D, Schürmann P, Rothämel T, Dörk T, Klintschar M., Free PMC Article | 06/11/2022 |
| Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury. | Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.
Jha RM, Zusman BE, Puccio AM, Okonkwo DO, Pease M, Desai SM, Leach M, Conley YP, Kochanek PM., Free PMC Article | 01/8/2022 |
| Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. | Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions.
Borgström A, Hauert B, Kappel S, Zoni E, Kiener M, Stokłosa P, Baur R, Spahn M, Kruithof-de Julio M, Peinelt C. | 10/23/2021 |
| TRPM4 non-selective cation channel in human atrial fibroblast growth. | TRPM4 non-selective cation channel in human atrial fibroblast growth.
Simard C, Magaud C, Adjlane R, Dupas Q, Sallé L, Manrique A, Bois P, Faivre JF, Guinamard R. | 09/25/2021 |
| TRPM4 Modulates Right Ventricular Remodeling Under Pressure Load Accompanied With Decreased Expression Level. | TRPM4 Modulates Right Ventricular Remodeling Under Pressure Load Accompanied With Decreased Expression Level.
Frede W, Medert R, Poth T, Gorenflo M, Vennekens R, Freichel M, Uhl S. | 09/18/2021 |
| Theoretical Investigation of the Mechanism by which A Gain-of-Function Mutation of the TRPM4 Channel Causes Conduction Block. | Theoretical Investigation of the Mechanism by which A Gain-of-Function Mutation of the TRPM4 Channel Causes Conduction Block.
Hu Y, Li Q, Shen Y, Fujita T, Zhu X, Inoue R., Free PMC Article | 09/18/2021 |
| Whole-Exome Sequencing Identifies a Novel TRPM4 Mutation in a Chinese Family with Atrioventricular Block. | Whole-Exome Sequencing Identifies a Novel TRPM4 Mutation in a Chinese Family with Atrioventricular Block.
Dong Y, Du R, Fan LL, Jin JY, Huang H, Chen YQ, Bi DD, Xiang R., Free PMC Article | 08/14/2021 |
| Aberrant TRPM4 expression in MLL-rearranged acute myeloid leukemia and its blockade induces cell cycle arrest via AKT/GLI1/Cyclin D1 pathway. | Aberrant TRPM4 expression in MLL-rearranged acute myeloid leukemia and its blockade induces cell cycle arrest via AKT/GLI1/Cyclin D1 pathway.
Wang F, Wu P, Gong S, Chen Y, Gao J, Wang S, Shen Q, Tao H, Hua F, Zhou Z, Zou Z, Ma T, Jia Y. | 08/7/2021 |
| TRPM4 in Cancer-A New Potential Drug Target. | TRPM4 in Cancer-A New Potential Drug Target.
Borgström A, Peinelt C, Stokłosa P., Free PMC Article | 07/3/2021 |
| Domain zipping and unzipping modulates TRPM4's properties in human cardiac conduction disease. | Domain zipping and unzipping modulates TRPM4's properties in human cardiac conduction disease.
Xian W, Wang H, Moretti A, Laugwitz KL, Flockerzi V, Lipp P. | 03/13/2021 |
| KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis. | KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis.
Rivas J, Díaz N, Silva I, Morales D, Lavanderos B, Álvarez A, Saldías MP, Pulgar E, Cruz P, Maureira D, Flores G, Colombo A, Blanco C, Contreras HR, Jaña F, Gallegos I, Concha ML, Vergara-Jaque A, Poblete H, González W, Varela D, Trimmer JS, Cáceres M, Cerda O. | 01/23/2021 |
| Molecular and genetic insights into progressive cardiac conduction disease. | Molecular and genetic insights into progressive cardiac conduction disease.
Asatryan B, Medeiros-Domingo A. | 12/5/2020 |
| Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury. | Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury.
Jha RM, Desai SM, Zusman BE, Koleck TA, Puccio AM, Okonkwo DO, Park SY, Shutter LA, Kochanek PM, Conley YP., Free PMC Article | 10/31/2020 |
| Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion. | Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion.
Gerzanich V, Stokum JA, Ivanova S, Woo SK, Tsymbalyuk O, Sharma A, Akkentli F, Imran Z, Aarabi B, Sahuquillo J, Simard JM., Free PMC Article | 08/29/2020 |
| TRPM4 is overexpressed in breast cancer associated with estrogen response and epithelial-mesenchymal transition gene sets. | TRPM4 is overexpressed in breast cancer associated with estrogen response and epithelial-mesenchymal transition gene sets.
Wong KK, Hussain FA., Free PMC Article | 08/22/2020 |
| TRPM4 plays a versatile role in cancer cell proliferation, cell cycle, and invasion. | TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells.
Kappel S, Stokłosa P, Hauert B, Ross-Kaschitza D, Borgström A, Baur R, Galván JA, Zlobec I, Peinelt C., Free PMC Article | 06/20/2020 |
| Progressive symmetric erythrokeratodermia: Activating mutations of TRPM4 | [Progressive symmetric erythrokeratodermia: Activating mutations of TRPM4].
Dereure O. | 02/22/2020 |
| To evaluate whether TRPM4 overexpression was related to the spreading capability of tumors, TRPM4 was knocked down by using shRNAs in PC3 prostate cancer cells and the effect on cellular migration and invasion was analyzed. PC3 cells with reduced levels of TRPM4 (shTRPM4) display a decrease of the migration/invasion capability. | TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines.
Sagredo AI, Sagredo EA, Pola V, Echeverría C, Andaur R, Michea L, Stutzin A, Simon F, Marcelain K, Armisén R. | 01/4/2020 |