| Evaluating the Molecular Properties and Function of ANKHD1, and Its Role in Cancer. | Evaluating the Molecular Properties and Function of ANKHD1, and Its Role in Cancer.
Mullenger JL, Zeidler MP, Fragiadaki M., Free PMC Article | 08/30/2023 |
| The feedback loop of ANKHD1/lncRNA MALAT1/YAP1 strengthens the radioresistance of CRC by activating YAP1/AKT signaling. | The feedback loop of ANKHD1/lncRNA MALAT1/YAP1 strengthens the radioresistance of CRC by activating YAP1/AKT signaling.
Yao PA, Wu Y, Zhao K, Li Y, Cao J, Xing C., Free PMC Article | 03/26/2022 |
| Emerging functions for ANKHD1 in cancer-related signaling pathways and cellular processes. | Emerging functions for ANKHD1 in cancer-related signaling pathways and cellular processes.
Almeida BO, Machado-Neto JA., Free PMC Article | 05/29/2021 |
| ANKHD1 promotes proliferation and invasion of nonsmallcell lung cancer cells via regulating YAP oncoprotein expression and inactivating the Hippo pathway. | ANKHD1 promotes proliferation and invasion of non‑small‑cell lung cancer cells via regulating YAP oncoprotein expression and inactivating the Hippo pathway.
Liu XF, Han Q, Rong XZ, Yang M, Han YC, Yu JH, Lin XY., Free PMC Article | 02/13/2021 |
| ANKHD1 is an S phase protein required for histone synthesis and DNA repair in multiple myeloma cells. | ANKHD1 is an S phase protein required for histone synthesis and DNA repair in multiple myeloma cells.
Dhyani A, Favaro P, Olalla Saad ST. | 01/16/2021 |
| we identified ANKHD1 as a co-regulator with SMYD3. We provided evidence that SMYD3 transactivates its target genes and promotes HCC cells migration and invasion through ANKHD1. | ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma.
Zhou Z, Jiang H, Tu K, Yu W, Zhang J, Hu Z, Zhang H, Hao D, Huang P, Wang J, Wang A, Xiao Z, He C., Free PMC Article | 04/13/2019 |
| High ANKHD1 expression is associated with renal cancer. | Ankyrin repeat and single KH domain 1 (ANKHD1) drives renal cancer cell proliferation via binding to and altering a subset of miRNAs.
Fragiadaki M, Zeidler MP., Free PMC Article | 01/26/2019 |
| ANKHD1 may be an oncogene and participate in the leukemia cell phenotype. | ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells.
Machado-Neto JA, Lazarini M, Favaro P, de Melo Campos P, Scopim-Ribeiro R, Franchi Junior GC, Nowill AE, Lima PR, Costa FF, Benichou S, Olalla Saad ST, Traina F. | 09/26/2015 |
| Data suggest an association of ANKHD1 (Ankyrin repeat and KH domain-containing protein 1) protein with p21 (WAF1/CIP1) promoter region. | ANKHD1 represses p21 (WAF1/CIP1) promoter and promotes multiple myeloma cell growth.
Dhyani A, Machado-Neto JA, Favaro P, Saad ST. | 05/2/2015 |
| ANKHD1 is a positive regulator of YAP1 and promotes cell growth and cell cycle progression through Cyclin A upregulation. | ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells.
Machado-Neto JA, Lazarini M, Favaro P, Franchi GC Jr, Nowill AE, Saad ST, Traina F. | 07/12/2014 |
| These data suggest that ANKHD1 might have a role in multiple myeloma cell proliferation and cell cycle progression by regulating expression of p21. | ANKHD1 regulates cell cycle progression and proliferation in multiple myeloma cells.
Dhyani A, Duarte AS, Machado-Neto JA, Favaro P, Ortega MM, Olalla Saad ST. | 02/23/2013 |
| identification of new splice variant with upregulation of its mRNA considerably higher than other variants during erythroid differentiation | Characterisation of a new splice variant of MASK-BP3(ARF) and MASK human genes, and their expression patterns during haematopoietic cell differentiation.
Santos Duarte Ada S, Traina F, Favaro PM, Bassères DS, de Carvalho IC, Medina Sde S, Costa FF, Saad ST. | 01/21/2010 |
| VBARP is a novel splice variant of ANKHD1 and may play a role in cellular apoptosis (antiapoptotic) and cell survival pathway(s | Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis.
Miles MC, Janket ML, Wheeler ED, Chattopadhyay A, Majumder B, Dericco J, Schafer EA, Ayyavoo V. | 01/21/2010 |
| These findings suggest a role for ANKHD1 as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. | ANKHD1, ankyrin repeat and KH domain containing 1, is overexpressed in acute leukemias and is associated with SHP2 in K562 cells.
Traina F, Favaro PM, Medina Sde S, Duarte Ada S, Winnischofer SM, Costa FF, Saad ST. | 01/21/2010 |