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    NCAPG2 non-SMC condensin II complex subunit G2 [ Homo sapiens (human) ]

    Gene ID: 54892, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling.

    NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signaling.
    Zhang E, Chen Z, Liu W, Lin L, Wu L, Guan J, Wang J, Kong C, Bi J, Zhang M., Free PMC Article

    01/17/2024
    The mRNA stability of NCAPG2, a novel contributor to breast invasive carcinoma, is enhanced by the RNA-binding protein PCBP2.

    The mRNA stability of NCAPG2, a novel contributor to breast invasive carcinoma, is enhanced by the RNA-binding protein PCBP2.
    Han S, Jin X, Hu T, Chi F.

    09/1/2023
    Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis.

    Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis.
    Wang W, Luo H, Chang J, Yang X, Zhang X, Zhang Q, Li Y, Zhao Y, Liu J, Zou B, Hao M., Free PMC Article

    06/2/2023
    NCAPG2 contributes to the progression of malignant melanoma through regulating proliferation and metastasis.

    NCAPG2 contributes to the progression of malignant melanoma through regulating proliferation and metastasis.
    Feng Z, Zhang L, Liu Y, Zhang W.

    12/3/2022
    microRNA-375 inhibits the malignant behaviors of hepatic carcinoma cells by targeting NCAPG2.

    microRNA-375 inhibits the malignant behaviors of hepatic carcinoma cells by targeting NCAPG2.
    Dai HT, Wang ST, Chen B, Tang KY, Li N, Wen CY, Wan Y, Zhang GY, Huang YH, Geng ZJ.

    02/19/2022
    NCAPG2 facilitates glioblastoma cells' malignancy and xenograft tumor growth via HBO1 activation by phosphorylation.

    NCAPG2 facilitates glioblastoma cells' malignancy and xenograft tumor growth via HBO1 activation by phosphorylation.
    Wu J, Li L, Jiang G, Zhan H, Zhu X, Yang W.

    09/25/2021
    that NCAPG2 is an important oncogene that contributes to HCC proliferation and metastasis. NCAPG2 can activate both the STAT3 and NF-kappaB pathways and activated STAT3 positively regulates NCAPG2 expression.

    NCAPG2 overexpression promotes hepatocellular carcinoma proliferation and metastasis through activating the STAT3 and NF-κB/miR-188-3p pathways.
    Meng F, Zhang S, Song R, Liu Y, Wang J, Liang Y, Wang J, Han J, Song X, Lu Z, Yang G, Pan S, Li X, Liu Y, Zhou F, Wang Y, Cui Y, Zhang B, Ma K, Zhang C, Sun Y, Xin M, Liu L., Free PMC Article

    12/21/2019
    data suggest that impaired function of NCAPG2 results in a severe condensinopathy, and they highlight the potential utility of examining candidate pathogenic lesions beyond the primary disease locus

    Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies.
    Khan TN, Khan K, Sadeghpour A, Reynolds H, Perilla Y, McDonald MT, Gallentine WB, Baig SM, Task Force for Neonatal Genomics, Davis EE, Katsanis N., Free PMC Article

    11/9/2019
    increased NCAPG2 expression could regulate cell proliferation and identified as a poor prognostic biomarker in lung adenocarcinoma.

    NCAPG2 promotes tumour proliferation by regulating G2/M phase and associates with poor prognosis in lung adenocarcinoma.
    Zhan P, Xi GM, Zhang B, Wu Y, Liu HB, Liu YF, Xu WJ, Zhu Q, Cai F, Zhou ZJ, Miu YY, Wang XX, Jin JJ, Li Q, Lv TF, Song Y., Free PMC Article

    08/12/2017
    Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair

    Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.
    Wood JL, Liang Y, Li K, Chen J., Free PMC Article

    01/21/2010
    The CAP-G2 subunit of the condensin II complex implicated in chromosome assembly and segregation

    Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.
    Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T.

    07/5/2005
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