| STEAP3 promotes colon cancer cell proliferation and migration via regulating histone acetylation. | STEAP3 promotes colon cancer cell proliferation and migration via regulating histone acetylation.
Lv J, Liu X, Sun Z, Gao J, Yu X, Zhang M, Zhang Z, Ren S, Zuo Y. | 05/3/2024 |
| STEAP3 Affects Ovarian Cancer Progression by Regulating Ferroptosis through the p53/SLC7A11 Pathway. | STEAP3 Affects Ovarian Cancer Progression by Regulating Ferroptosis through the p53/SLC7A11 Pathway.
Han Y, Fu L, Kong Y, Jiang C, Huang L, Zhang H., Free PMC Article | 03/6/2024 |
| Six-Transmembrane Epithelial Antigen of Prostate 3 Promotes Hepatic Insulin Resistance and Steatosis. | Six-Transmembrane Epithelial Antigen of Prostate 3 Promotes Hepatic Insulin Resistance and Steatosis.
Ding T, Chen S, Xiao W, Liu Z, Tu J, Yu Y, Dong B, Chen W, Zeng Y., Free PMC Article | 02/4/2023 |
| STEAP3 Affects Ferroptosis and Progression of Renal Cell Carcinoma Through the p53/xCT Pathway. | STEAP3 Affects Ferroptosis and Progression of Renal Cell Carcinoma Through the p53/xCT Pathway.
Ye CL, Du Y, Yu X, Chen ZY, Wang L, Zheng YF, Liu XH., Free PMC Article | 05/7/2022 |
| Predictive potential of STEAP family for survival, immune microenvironment and therapy response in glioma. | Predictive potential of STEAP family for survival, immune microenvironment and therapy response in glioma.
Zhao Z, Wang Z, Song Z, Wu Y, Jin Q, Zhao Z. | 03/19/2022 |
| STEAP3 promotes cancer cell proliferation by facilitating nuclear trafficking of EGFR to enhance RAC1-ERK-STAT3 signaling in hepatocellular carcinoma. | STEAP3 promotes cancer cell proliferation by facilitating nuclear trafficking of EGFR to enhance RAC1-ERK-STAT3 signaling in hepatocellular carcinoma.
Wang LL, Luo J, He ZH, Liu YQ, Li HG, Xie D, Cai MY., Free PMC Article | 02/5/2022 |
| This article is the first report of a role of Steap3 in mature RBCs; it defines a new mechanism of redox biology in RBCs with a substantial effect upon RBC function and provides a novel mechanistic determinant of genetic variation of RBC storage. | Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.
Howie HL, Hay AM, de Wolski K, Waterman H, Lebedev J, Fu X, Culp-Hill R, D'Alessandro A, Gorham JD, Ranson MS, Roback JD, Thomson PC, Zimring JC., Free PMC Article | 08/1/2020 |
| this study identified oxidative stress-dependent upregulation of the iron-converting metalloreductase, STEAP3, as a key mediator of extracellular matrix production in wound healing | Reduced Iron in Diabetic Wounds: An Oxidative Stress-Dependent Role for STEAP3 in Extracellular Matrix Deposition and Remodeling.
Wilkinson HN, Upson SE, Banyard KL, Knight R, Mace KA, Hardman MJ. | 06/13/2020 |
| In hepatocellular carcinoma (HCC), lower expression of the STEAP3 copper reductase and heavy Cu isotope enrichment have been reported for the tumor mass, relative to the surrounding tissue | Copper transporters are responsible for copper isotopic fractionation in eukaryotic cells.
Cadiou JL, Pichat S, Bondanese VP, Soulard A, Fujii T, Albarède F, Oger P., Free PMC Article | 11/10/2018 |
| TSAP6 over expression is associated with poor survival in metastatic high-grade serous carcinoma. | TSAP6 is a novel candidate marker of poor survival in metastatic high-grade serous carcinoma.
Broner EC, Tropé CG, Reich R, Davidson B. | 09/2/2017 |
| heterozygous STEAP3 mutations are relatively common in humans and that their deleterious effect in humans remains to be confirmed | Human STEAP3 mutations with no phenotypic red cell changes.
Liu D, Yi S, Zhang X, Fang P, Zheng C, Lin L, Cai R, Ye Y, Zhou Y, Liang Y, Cheng F, Zhang X, Zhou W, Mohandas N, An X, Xu X., Free PMC Article | 08/13/2016 |
| TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis. | Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis.
Wan C, Fu J, Wang Y, Miao S, Song W, Wang L., Free PMC Article | 09/22/2012 |
| findings indicate that STEAP3 maintains iron storage in human malignant cells and tumor proliferation under the hypoferric condition | Human STEAP3 maintains tumor growth under hypoferric condition.
Isobe T, Baba E, Arita S, Komoda M, Tamura S, Shirakawa T, Ariyama H, Takaishi S, Kusaba H, Ueki T, Akashi K. | 01/14/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.
Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Dorak MT. | 09/15/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Down-regulated expression of the TSAP6 protein in liver is associated with a transition from cirrhosis to hepatocellular carcinoma | Down-regulated expression of the TSAP6 protein in liver is associated with a transition from cirrhosis to hepatocellular carcinoma.
Caillot F, Daveau R, Daveau M, Lubrano J, Saint-Auret G, Hiron M, Goria O, Scotte M, Francois A, Salier JP. | 01/21/2010 |
| The crystal structure of the human Steap3 oxidoreductase domain in the absence and presence of NADPH was determined. | Structure of the membrane proximal oxidoreductase domain of human Steap3, the dominant ferrireductase of the erythroid transferrin cycle.
Sendamarai AK, Ohgami RS, Fleming MD, Lawrence CM., Free PMC Article | 01/21/2010 |
| role for TSAP6 in the export of TCTP and indicate that this multipass membrane protein could have a general role in the regulation of vesicular trafficking and secretion. | TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway.
Amzallag N, Passer BJ, Allanic D, Segura E, Théry C, Goud B, Amson R, Telerman A. | 01/21/2010 |
| TSAP6 may augment Myt1 activity and act downstream to p53 to interface apoptosis and cell-cycle progression | The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.
Passer BJ, Nancy-Portebois V, Amzallag N, Prieur S, Cans C, Roborel de Climens A, Fiucci G, Bouvard V, Tuynder M, Susini L, Morchoisne S, Crible V, Lespagnol A, Dausset J, Oren M, Amson R, Telerman A., Free PMC Article | 01/21/2010 |