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    RNLS renalase, FAD dependent amine oxidase [ Homo sapiens (human) ]

    Gene ID: 55328, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Coexistence of Cardiovascular Risk Factors and Blood Renalase Concentration.

    Coexistence of Cardiovascular Risk Factors and Blood Renalase Concentration.
    Żórawik A, Hajdusianek W, Markiewicz-Górka I, Jaremków A, Pawlas K, Martynowicz H, Mazur G, Poręba R, Gać P., Free PMC Article

    12/20/2023
    [The association of renalase single-nucleotide polymorphisms rs2576178 and rs10887800 with hypertension in patients with obstructive sleep apnea].

    [The association of renalase single-nucleotide polymorphisms rs2576178 and rs10887800 with hypertension in patients with obstructive sleep apnea].
    Yang JD, Xue WJ, Wei ZC, Hou CQ, Li XY, Xu HH, Wu XL, Feng YH, Yin SK.

    11/3/2023
    The Multi-Faceted Nature of Renalase for Mitochondrial Dysfunction Improvement in Cardiac Disease.

    The Multi-Faceted Nature of Renalase for Mitochondrial Dysfunction Improvement in Cardiac Disease.
    Stojanovic D, Stojanovic M, Milenkovic J, Velickov A, Ignjatovic A, Milojkovic M., Free PMC Article

    06/30/2023
    Role of serum renalase levels in predicting the presence of metabolic syndrome in patients with polycystic ovary syndrome.

    Role of serum renalase levels in predicting the presence of metabolic syndrome in patients with polycystic ovary syndrome.
    Ersak B, Özakşit G, Tugrul D, Doğanay M, Ustun Y, Kokanalı MK.

    05/25/2023
    Plasma renalase levels are associated with the development of acute pancreatitis.

    Plasma renalase levels are associated with the development of acute pancreatitis.
    Wang M, Weiss FU, Guo X, Kolodecik T, Bewersdorf JP, Laine L, Lerch MM, Desir G, Gorelick FS.

    03/9/2023
    Renalase and its receptor, PMCA4b, are expressed in the placenta throughout the human gestation.

    Renalase and its receptor, PMCA4b, are expressed in the placenta throughout the human gestation.
    Wang M, Silva T, Toothaker JM, McCourt BT, Shugrue C, Desir G, Gorelick F, Konnikova L., Free PMC Article

    05/7/2022
    Evaluation of the association of the Renalase rs10887800 polymorphism with the risk of preeclampsia in Brazilian women.

    Evaluation of the association of the Renalase rs10887800 polymorphism with the risk of preeclampsia in Brazilian women.
    de Freitas Moura MS, Linhares JJ, Noronha EC, de Pina Fernandes WC, Simiano Tavares KC, Marcelo Antunes ASL, Benevides SC, Barbalho Silva AW.

    02/26/2022
    The Effect of Renalase rs2576178 and rs10887800 Polymorphisms on Ischemic Stroke Susceptibility in Young Patients (<50 Years): A Case-Control Study and In Silico Analysis.

    The Effect of Renalase rs2576178 and rs10887800 Polymorphisms on Ischemic Stroke Susceptibility in Young Patients (<50 Years): A Case-Control Study and In Silico Analysis.
    Ramroodi N, Khorrami A, Hashemi SM, Rezaei M, Shahraki-Ghadim H, Salimi S., Free PMC Article

    02/5/2022
    Renalase gene polymorphisms and plasma levels are associated with preeclampsia: a hospital-based study in the Chinese cohort.

    Renalase gene polymorphisms and plasma levels are associated with preeclampsia: a hospital-based study in the Chinese cohort.
    Li X, Huang Q, Xu J.

    02/5/2022
    Elevated Levels of Renalase, the beta-NAD(P)H Isomerase, Can Be Used as Risk Factors of Major Adverse Cardiovascular Events and All-Cause Death in Patients with Chronic Kidney Disease.

    Elevated Levels of Renalase, the β-NAD(P)H Isomerase, Can Be Used as Risk Factors of Major Adverse Cardiovascular Events and All-Cause Death in Patients with Chronic Kidney Disease.
    Knop W, Serwin NM, Cecerska-Heryć E, Grygorcewicz B, Dołęgowska B, Gomółka A, Wiśniewska M, Ciechanowski K., Free PMC Article

    01/22/2022
    Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.

    Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus.
    Buraczynska M, Gwiazda-Tyndel K, Drop B, Zaluska W., Free PMC Article

    12/11/2021
    Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma.

    Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma.
    Gao Y, Wang M, Guo X, Hu J, Chen TM, Finn SMB, Lacy J, Kunstman JW, Cha CH, Bellin MD, Robert ME, Desir GV, Gorelick FS., Free PMC Article

    11/13/2021
    Association of renalase gene polymorphisms with the risk of hypertensive disorders of pregnancy in northeastern Han Chinese population.

    Association of renalase gene polymorphisms with the risk of hypertensive disorders of pregnancy in northeastern Han Chinese population.
    Zhang F, Liu W, Wu Y, Li X, Zhang S, Feng Y, Lu R, Sun L.

    08/28/2021
    Renalase rs10887800 polymorphism is associated with severe pre-eclampsia in southeast Iranian women

    Renalase rs10887800 polymorphism is associated with severe pre-eclampsia in southeast Iranian women.
    Teimoori B, Moradi-Shahrebabak M, Rezaei M, Mohammadpour-Gharehbagh A, Salimi S.

    06/27/2020
    Plasma renalase concentrations positively correlated with left ventricle hypertrophy in patients with reduced ejection fraction, being strongly associated with increased left ventricular mass index.

    Association of Plasma Renalase and Left Ventricle Mass Index in Heart Failure Patients Stratified to the Category of the Ejection Fraction: A Pilot Study.
    Stojanovic D, Mitic V, Petrovic D, Stojanovic M, Ignjatovic A, Stefanovic N, Cvetkovic T, Bojanic V, Kocic G, Ilic MD., Free PMC Article

    05/2/2020
    Expression of single nucleotide polymorphism rs2237895 and rs2576178 in both KCNQ1 and Renalase genes might be responsible for altering reproductive potential, hence leading to infertility in women in Pakistan.

    Single nucleotide polymorphisms in Renalase and KCNQ1 genes and female infertility: A cross-sectional study in Pakistan.
    Fatima SS, Rehman R, Martins RS, Alam F, Ashraf M.

    04/4/2020
    In children with chronic kidney disease there is a strong correlation between renalase level and CKD stage; may be a marker of arterial stiffness.

    Renalase in children with chronic kidney disease.
    Skrzypczyk P, Okarska-Napierała M, Stelmaszczyk-Emmel A, Górska E, Pańczyk-Tomaszewska M.

    02/15/2020
    Elevated circulating renalase might be a predictor of mortality and adverse renal outcomes in patients with chronic kidney disease.

    Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease.
    Baek SH, Cha RH, Kang SW, Park CW, Cha DR, Kim SG, Yoon SA, Kim S, Han SY, Park JH, Chang JH, Lim CS, Kim YS, Na KY., Free PMC Article

    02/1/2020
    Serum levels of renalase were elevated in patients with acute coronary microvascular dysfunction.

    Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia.
    Safdar B, Guo X, Johnson C, D'Onofrio G, Dziura J, Sinusas AJ, Testani J, Rao V, Desir G., Free PMC Article

    12/7/2019
    Renalase rs2576178 polymorphism is associated with increased risk of coronary artery disease , but this finding should be confirmed by larger studies with more diverse ethnic populations

    Investigation of Renalase gene rs2576178 polymorphism in patients with coronary artery disease.
    Hu N, Wang J, Hu P, Li Z., Free PMC Article

    05/18/2019
    Low renalase level may be associated with impaired rate control, higher atrial fibrillation (AF) burden, and advanced left atrial remodelling in AF patients undergoing pulmonary vein isolation, but it does not predict sinus rhythm maintenance.

    Renalase is associated with adverse left atrial remodelling and disease burden in patients with atrial fibrillation undergoing pulmonary vein isolation.
    Wybraniec MT, Wieczorek J, Woźniak-Skowerska I, Hoffmann A, Nowak S, Cichoń M, Szydło K, Wnuk-Wojnar A, Chudek J, Więcek A, Mizia-Stec K.

    01/5/2019
    Data (including data from studies in knockout mice) suggest that renalase functions as a protective plasma protein that reduces pancreatic acinar cell injury and prevents pancreatitis via interactions with plasma membrane calcium ATPase PMCA4b.

    The serum protein renalase reduces injury in experimental pancreatitis.
    Kolodecik TR, Reed AM, Date K, Shugrue CA, Patel V, Chung SL, Desir GV, Gorelick FS., Free PMC Article

    11/17/2018
    renalase may reduce renal tubular injury and apoptosis of renal tubular epithelial cells.

    Relationship between Renalase Expression and Kidney Disease: an Observational Study in 72 Patients Undergoing Renal Biopsy.
    Huang YS, Lai JB, Li SF, Wang T, Liu YN, Zhang QX, Zhang SY, Sun CH, Hu N, Zhang XZ.

    11/3/2018
    Urinary renalase concentration is reduced in the aftermath of coronary angiography/percutaneous coronary intervention, which may be related to contrast induced-acute kidney injury development.

    Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography.
    Wybraniec MT, Bożentowicz-Wikarek M, Chudek J, Mizia-Stec K.

    09/1/2018
    we focus on the cytoprotective actions of renalase and its capacity to sustain cancer cell growth and also the translational opportunities these findings represent for the development of novel therapeutic strategies for organ injury and cancer

    Extracellular renalase protects cells and organs by outside-in signalling.
    Wang Y, Safirstein R, Velazquez H, Guo XJ, Hollander L, Chang J, Chen TM, Mu JJ, Desir GV., Free PMC Article

    03/24/2018
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