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    MEG3 maternally expressed 3 [ Homo sapiens (human) ]

    Gene ID: 55384, updated on 5-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MEG3 in hematologic malignancies: from the role of disease biomarker to therapeutic target.

    MEG3 in hematologic malignancies: from the role of disease biomarker to therapeutic target.
    Zhang C, Qin Y, Tang Y, Gu M, Li Z, Xu H.

    07/31/2024
    Multifaceted roles of Meg3 in cellular senescence and atherosclerosis.

    Multifaceted roles of Meg3 in cellular senescence and atherosclerosis.
    Cheng X, Shihabudeen Haider Ali MS, Baki VB, Moran M, Su H, Sun X., Free PMC Article

    07/9/2024
    Long non-coding RNA MEG3 knockdown represses airway smooth muscle cells proliferation and migration via sponging miR-143-3p/FGF9 in asthma.

    Long non-coding RNA MEG3 knockdown represses airway smooth muscle cells proliferation and migration via sponging miR-143-3p/FGF9 in asthma.
    Gu J, Zhou D., Free PMC Article

    06/10/2024
    MEG3 shuttled by exosomes released from human bone marrow mesenchymal stem cells promotes TP53 stability to regulate MCM5 transcription in keloid fibroblasts.

    MEG3 shuttled by exosomes released from human bone marrow mesenchymal stem cells promotes TP53 stability to regulate MCM5 transcription in keloid fibroblasts.
    Zhu F, Ye Y, Shao Y, Xue C.

    05/3/2024
    RhoGDIbeta inhibition via miR-200c/AUF1/SOX2/miR-137 axis contributed to lncRNA MEG3 downregulation-mediated malignant transformation of human bronchial epithelial cells.

    RhoGDIβ inhibition via miR-200c/AUF1/SOX2/miR-137 axis contributed to lncRNA MEG3 downregulation-mediated malignant transformation of human bronchial epithelial cells.
    Yang Y, Tian Z, He L, Meng H, Xie X, Yang Z, Wang X, Zhao Y, Huang C.

    04/25/2024
    Harnessing the supremacy of MEG3 LncRNA to defeat gastrointestinal malignancies.

    Harnessing the supremacy of MEG3 LncRNA to defeat gastrointestinal malignancies.
    Rashwan HH, Taher AM, Hassan HA, Awaji AA, Kiriacos CJ, Assal RA, Youness RA.

    04/18/2024
    Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer.

    Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer.
    Lian Z, Tian P, Ma S, Chang T, Liu R, Feng Q, Li J., Free PMC Article

    03/6/2024
    Novel genetic markers for chronic kidney disease in a geographically isolated population of Indigenous Australians: Individual and multiple phenotype genome-wide association study.

    Novel genetic markers for chronic kidney disease in a geographically isolated population of Indigenous Australians: Individual and multiple phenotype genome-wide association study.
    Arunachalam V, Lea R, Hoy W, Lee S, Mott S, Savige J, Mathews JD, McMorran BJ, Nagaraj SH., Free PMC Article

    03/4/2024
    m[6]A methylation-mediated regulation of LncRNA MEG3 suppresses ovarian cancer progression through miR-885-5p and the VASH1 pathway.

    m(6)A methylation-mediated regulation of LncRNA MEG3 suppresses ovarian cancer progression through miR-885-5p and the VASH1 pathway.
    Li Y, Lou S, Zhang J, Zhao S, Lou G., Free PMC Article

    02/29/2024
    Changes in Serum LncRNA MEG3/miR-181b and UCH-L1 Levels in Patients with Moderate and Severe Intracerebral Hemorrhage.

    Changes in Serum LncRNA MEG3/miR-181b and UCH-L1 Levels in Patients with Moderate and Severe Intracerebral Hemorrhage.
    Wang H, Wang L, Shi Q.

    02/7/2024
    LncRNA MEG3 suppresses erastin-induced ferroptosis of chondrocytes via regulating miR-885-5p/SLC7A11 axis.

    LncRNA MEG3 suppresses erastin-induced ferroptosis of chondrocytes via regulating miR-885-5p/SLC7A11 axis.
    Zhu C, Chen B, He X, Li W, Wang S, Zhu X, Li Y, Wan P, Li X.

    02/7/2024
    Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1.

    Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1.
    Yi D, Wang Z, Yang H, Wang R, Shi X, Liu Z, Xu F, Lu Q, Chu X, Sang J., Free PMC Article

    02/6/2024
    HGF facilitates methylation of MEG3, potentially implicated in vemurafenib resistance in melanoma.

    HGF facilitates methylation of MEG3, potentially implicated in vemurafenib resistance in melanoma.
    Jia X, Feng H, He S, Chen X, Feng H, Chen M, Hu X.

    02/5/2024
    Altered expression of long noncoding RNA MEG3 in the offspring of gestational diabetes mellitus induces impaired glucose tolerance in adulthood.

    Altered expression of long noncoding RNA MEG3 in the offspring of gestational diabetes mellitus induces impaired glucose tolerance in adulthood.
    Yang MM, Wei J, Xu LL, Yan YS, Chen Y, Lv M, Jiang Y, Luo Q.

    02/2/2024
    [Long Noncoding RNAs MEG3, TUG1, and hsa-miR-21-3p Are Potential Diagnostic Biomarkers for Coronary Artery Disease].

    [Long Noncoding RNAs MEG3, TUG1, and hsa-miR-21-3p Are Potential Diagnostic Biomarkers for Coronary Artery Disease].
    Abdelgawad M, Abdallah HY, Fareed A, Ahmed AE.

    01/5/2024
    The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis.

    The lncRNA MEG3/miRNA-21/P38MAPK axis inhibits coxsackievirus 3 replication in acute viral myocarditis.
    He F, Liu Z, Feng M, Xiao Z, Yi X, Wu J, Liu Z, Wang G, Li L, Yao H., Free PMC Article

    12/28/2023
    APOE-mediated suppression of the lncRNA MEG3 protects human cardiovascular cells from chronic inflammation.

    APOE-mediated suppression of the lncRNA MEG3 protects human cardiovascular cells from chronic inflammation.
    Zhao H, Yang K, Zhang Y, Li H, Ji Q, Wu Z, Ma S, Wang S, Song M, Liu GH, Liu Q, Zhang W, Qu J., Free PMC Article

    12/5/2023
    The complex role of MEG3: An emerging long non-coding RNA in breast cancer.

    The complex role of MEG3: An emerging long non-coding RNA in breast cancer.
    Hussain MS, Majami AA, Ali H, Gupta G, Almalki WH, Alzarea SI, Kazmi I, Syed RU, Khalifa NE, Bin Break MK, Khan R, Altwaijry N, Sharma R.

    11/18/2023
    The ceRNA Mechanism of lncRNA MEG3/miR-21-5p/SPRY2 in Cell Proliferation and Apoptosis in Bladder Cancer.

    The ceRNA Mechanism of lncRNA MEG3/miR-21-5p/SPRY2 in Cell Proliferation and Apoptosis in Bladder Cancer.
    Hong Y, Li Z, Su Y, Pu H, Zhang X.

    11/18/2023
    The Meaningful Function of the Emerging Clinical Targets-lncRNA MEG3 in Gastric Cancer.

    The Meaningful Function of the Emerging Clinical Targets-lncRNA MEG3 in Gastric Cancer.
    Zhang Y, Wang Y, Jiang Y, Bai H, Wen Y.

    11/3/2023
    MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.

    MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
    Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B., Free PMC Article

    09/18/2023
    Expression pattern of long non-coding RNAs MALAT1 and MEG3 in COVID-19 patients.

    Expression pattern of long non-coding RNAs MALAT1 and MEG3 in COVID-19 patients.
    Genena SESR, Fadhil MM, Mansour MM, Attwa AHM, Khalil MMIM.

    09/8/2023
    Silencing of the MEG3 gene promoted anti-cancer activity and drug sensitivity in glioma.

    Silencing of the MEG3 gene promoted anti-cancer activity and drug sensitivity in glioma.
    Degirmenci Z, Unver S, Kilic T, Avsar T., Free PMC Article

    09/1/2023
    Role of MEG3 in Cellular Physiology of Atherosclerosis.

    Role of MEG3 in Cellular Physiology of Atherosclerosis.
    Wu YT, Guo ZJ, Li JB, Ye ZR, Zhang GX, Hong CM, Li M, Wang XW, Xu WF, Liang GT, Lin HQ.

    08/30/2023
    Evaluation of the expression levels of lncRNAs H19 and MEG3 in patients with type 2 diabetes mellitus.

    Evaluation of the expression levels of lncRNAs H19 and MEG3 in patients with type 2 diabetes mellitus.
    Alrefai AA, Khader HF, Elbasuony HA, Elzorkany KM, Saleh AA.

    06/28/2023
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