| FOXA2 Suppression by TRIM36 Exerts Anti-Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4-Regulated Ferroptosis. | FOXA2 Suppression by TRIM36 Exerts Anti-Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4-Regulated Ferroptosis.
Liu X, Yan C, Chang C, Meng F, Shen W, Wang S, Zhang Y., Free PMC Article | 12/22/2023 |
| Genome-wide association study reveals HSF2, GJA1 and TRIM36 as susceptibility genes for preeclampsia: a community-based population study in Tianjin, China. | Genome-wide association study reveals HSF2, GJA1 and TRIM36 as susceptibility genes for preeclampsia: a community-based population study in Tianjin, China.
Cao Z, Ma L, Cai W, Niu X, Yang N, Ni J, Wang X, Wei M, Chen S, Li Y. | 09/27/2023 |
| Trigred motif 36 regulates neuroendocrine differentiation of prostate cancer via HK2 ubiquitination and GPx4 deficiency. | Trigred motif 36 regulates neuroendocrine differentiation of prostate cancer via HK2 ubiquitination and GPx4 deficiency.
Zhao X, Zhou T, Wang Y, Bao M, Ni C, Ding L, Sun S, Dong H, Li J, Liang C., Free PMC Article | 06/5/2023 |
| TRIM36 enhances lung adenocarcinoma radiosensitivity and inhibits tumorigenesis through promoting RAD51 ubiquitination and antagonizing hsa-miR-376a-5p. | TRIM36 enhances lung adenocarcinoma radiosensitivity and inhibits tumorigenesis through promoting RAD51 ubiquitination and antagonizing hsa-miR-376a-5p.
Yu S, Li W, Liu X, Zhang H, Liu X, Zhang LW. | 10/15/2022 |
| TRIM36 suppresses cell growth and promotes apoptosis in human esophageal squamous cell carcinoma cells by inhibiting Wnt/beta-catenin signaling pathway. | TRIM36 suppresses cell growth and promotes apoptosis in human esophageal squamous cell carcinoma cells by inhibiting Wnt/β-catenin signaling pathway.
Zhao B, Qiao G, Li J, Wang Y, Li X, Zhang H, Zhang L. | 09/17/2022 |
| TRIM36 is a novel androgen-responsive gene, and it dramatically enhanced the efficacy of anti-androgen drugs against prostate cancer. | TRIM36, a novel androgen-responsive gene, enhances anti-androgen efficacy against prostate cancer by inhibiting MAPK/ERK signaling pathways.
Liang C, Wang S, Qin C, Bao M, Cheng G, Liu B, Shao P, Lv Q, Song N, Hua L, Gu M, Li J, Wang Z., Free PMC Article | 08/3/2019 |
| Results suggest that high expression of TRIM36 is associated with favorable prognosis and that TRIM36 plays a tumor-suppressive role by inhibiting cell proliferation and migration as well as promoting apoptosis in prostate cancer. | Androgen-responsive tripartite motif 36 enhances tumor-suppressive effect by regulating apoptosis-related pathway in prostate cancer.
Kimura N, Yamada Y, Takayama KI, Fujimura T, Takahashi S, Kume H, Inoue S., Free PMC Article | 01/5/2019 |
| aberrant hypermethylation of TRIM36 might be involved in the acquisition of malignant phenotype and could be served as a biomarker for risk assessment of PAHs exposure | (TRIM36 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation).
He Z, Li D, Ma J, Chen L, Duan H, Zhang B, Gao C, Li J, Xing X, Zhao J, Wang S, Wang F, Zhang H, Li H, Chen S, Zeng X, Wang Q, Xiao Y, Zheng Y, Chen W. | 07/29/2017 |
| The siRNA knock down of TRIM36 in HeLa and LN229 cells also led to reduced cell proliferation and increased apoptosis. We suggest that microtubule disruption and disorganized spindles mediated by mutant TRIM36 affect neural cell proliferation during neural tube formation, leading to Anencephaly . | A homozygous mutation in TRIM36 causes autosomal recessive anencephaly in an Indian family.
Singh N, Kumble Bhat V, Tiwari A, Kodaganur SG, Tontanahal SJ, Sarda A, Malini KV, Kumar A, Singh N, Kumble Bhat V, Tiwari A, Kodaganur SG, Tontanahal SJ, Sarda A, Malini KV, Kumar A. | 05/20/2017 |
| TRIM36 is the causative gene for autosomal recessive anencephaly | A homozygous mutation in TRIM36 causes autosomal recessive anencephaly in an Indian family.
Singh N, Kumble Bhat V, Tiwari A, Kodaganur SG, Tontanahal SJ, Sarda A, Malini KV, Kumar A, Singh N, Kumble Bhat V, Tiwari A, Kodaganur SG, Tontanahal SJ, Sarda A, Malini KV, Kumar A. | 02/17/2017 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| TRIM36 has a ubiquitin ligase activity and interacts with centromere protein-H, potentially associated with chromosome segregation and its excess may cause chromosomal instability. | TRIM36 interacts with the kinetochore protein CENP-H and delays cell cycle progression.
Miyajima N, Maruyama S, Nonomura K, Hatakeyama S. | 01/21/2010 |
| The overexpression of the TRIM36 in the vast majority of prostate cancer suggest that this gene might be involved in the prostate tumorigenesis. | Cloning and characterisation of the RBCC728/TRIM36 zinc-binding protein from the tumor suppressor gene region at chromosome 5q22.3.
Balint I, Müller A, Nagy A, Kovacs G. | 01/21/2010 |
| molecular cloning and characterization of a human haprin ortholog. | Identification of human HAPRIN potentially involved in the acrosome reaction.
Kitamura K, Nishimura H, Nishimune Y, Tanaka H. | 01/21/2010 |