| PKCdelta serves as a potential biomarker and therapeutic target for microglia-mediated neuroinflammation in Alzheimer's disease. | PKCδ serves as a potential biomarker and therapeutic target for microglia-mediated neuroinflammation in Alzheimer's disease.
Du Y, Guo T, Hao Y, Li C, Tang L, Li X, Zhang X, Li L, Yao D, Xu X, Si H, Zhang J, Zhao N, Yu T, Zhao Y, Zhang W, Xu H., Free PMC Article | 10/7/2024 |
| PKCdelta-mediated SGLT1 upregulation confers the acquired resistance of NSCLC to EGFR TKIs. | PKCδ-mediated SGLT1 upregulation confers the acquired resistance of NSCLC to EGFR TKIs.
Chen CH, Wang BW, Hsiao YC, Wu CY, Cheng FJ, Hsia TC, Chen CY, Wang Y, Weihua Z, Chou RH, Tang CH, Chen YJ, Wei YL, Hsu JL, Tu CY, Hung MC, Huang WC., Free PMC Article | 08/28/2024 |
| Metabolic reprogramming contributes to radioprotection by protein kinase Cdelta. | Metabolic reprogramming contributes to radioprotection by protein kinase Cδ.
Ohm AM, Affandi T, Reisz JA, Caino MC, D'Alessandro A, Reyland ME., Free PMC Article | 06/5/2024 |
| Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression. | Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression.
Deng Y, Hou Z, Li Y, Yi M, Wu Y, Zheng Y, Yang F, Zhong G, Hao Q, Zhai Z, Wang M, Ma X, Kang H, Ji F, Dong C, Liu H, Dai Z., Free PMC Article | 02/20/2024 |
| Activated PRKCD-mediated neutrophil extracellular traps pathway may be the prothrombotic mechanism of neutrophils in polycythemia vera patients based on clinical retrospective analysis and bioinformatics study. | Activated PRKCD-mediated neutrophil extracellular traps pathway may be the prothrombotic mechanism of neutrophils in polycythemia vera patients based on clinical retrospective analysis and bioinformatics study.
Zhang Y, Chen K, Wang M, Wang Z, Wang D, Niu J, Yang E, Li Y, Sun Y, Zhao P, Liu W, Lv Y, Hu X. | 01/29/2024 |
| Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer. | Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer.
Chaib M, Holt JR, Fisher EL, Sipe LM, Bohm MS, Joseph SC, Simmons BW, Eugin Simon S, Yarbro JR, Tanveer U, Halle JL, Carson JA, Hollingsworth TJ, Wei Q, Rathmell JC, Thomas PG, Hayes DN, Makowski L., Free PMC Article | 01/3/2024 |
| TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin-proteasome-mediated degradation of PRKCD. | TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin‒proteasome-mediated degradation of PRKCD.
Sun L, Chen Y, Xia L, Wang J, Zhu J, Li J, Wang K, Shen K, Zhang D, Zhang G, Shi T, Chen W. | 12/14/2023 |
| Phenotypic Variability in PRKCD: a Review of the Literature. | Phenotypic Variability in PRKCD: a Review of the Literature.
Jefferson L, Ramanan AV, Jolles S, Bernatoniene J, Mathieu AL, Belot A, Roderick MR. | 12/6/2023 |
| Thrombin-Induced COX-2 Expression and PGE2 Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCdelta/Pyk2-Dependent AP-1 Pathway Modulation. | Thrombin-Induced COX-2 Expression and PGE(2) Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation.
Yang CC, Lee IT, Lin YJ, Wu WB, Hsiao LD, Yang CM., Free PMC Article | 10/30/2023 |
| Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells. | Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate Under BMP4 Induction From Human Pluripotent Stem Cells.
Godoy-Parejo C, Deng C, Xu J, Zhang Z, Ren Z, Ai N, Liu W, Ge W, Deng C, Xu X, Chin YE, Chen G. | 06/16/2023 |
| Inhibition of protein kinase C delta leads to cellular senescence to induce anti-tumor effects in colorectal cancer. | Inhibition of protein kinase C delta leads to cellular senescence to induce anti-tumor effects in colorectal cancer.
Shimoyama Y, Yamada K, Yoshida S, Kawamura A, Hannya Y, Imaizumi Y, Kumamoto T, Takeda Y, Shimoda M, Eto K, Yoshida K., Free PMC Article | 06/5/2023 |
| Compound Heterozygous Mutations in PRKCD Associated with Early-Onset Lupus and Severe and Invasive Infections in Siblings. | Compound Heterozygous Mutations in PRKCD Associated with Early-Onset Lupus and Severe and Invasive Infections in Siblings.
Roderick MR, Jefferson L, Renton W, Belot A, PRKCD Consortium. | 04/20/2023 |
| Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCdelta Activator. | Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCδ Activator.
Bessa C, Loureiro JB, Barros M, Isca VMS, Sardão VA, Oliveira PJ, Bernardino RL, Herman-de-Sousa C, Costa MA, Correia-de-Sá P, Alves MG, Rijo P, Saraiva L., Free PMC Article | 03/31/2023 |
| Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCdelta Activation. | Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation.
Imeri F, Stepanovska Tanturovska B, Manaila R, Pavenstädt H, Pfeilschifter J, Huwiler A., Free PMC Article | 03/1/2023 |
| Genetic association of PRKCD and CARD9 polymorphisms with Vogt-Koyanagi-Harada disease in the Chinese Han population. | Genetic association of PRKCD and CARD9 polymorphisms with Vogt-Koyanagi-Harada disease in the Chinese Han population.
Zhou C, Cai S, Xie Y, Zeng Z, Zhang J, Su G, Wu Q, Ye X, Cao Q, Yang P, Hu J., Free PMC Article | 02/15/2023 |
| PRKCD as a potential therapeutic target for chronic obstructive pulmonary disease. | PRKCD as a potential therapeutic target for chronic obstructive pulmonary disease.
Li S, Huang Q, Zhou D, He B. | 12/10/2022 |
| Extracellular PKCdelta signals to epidermal growth factor receptor for tumor proliferation in liver cancer cells. | Extracellular PKCδ signals to epidermal growth factor receptor for tumor proliferation in liver cancer cells.
Yamada K, Kizawa R, Yoshida A, Koizumi R, Motohashi S, Shimoyama Y, Hannya Y, Yoshida S, Oikawa T, Shimoda M, Yoshida K., Free PMC Article | 07/23/2022 |
| The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion. | The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion.
Hernández-Rojas R, Jiménez-Arellano C, de la Fuente-Granada M, Ordaz-Rosado D, García-Becerra R, Valencia-Mayoral P, Álvarez-Arellano L, Eguía-Aguilar P, Velasco-Velázquez MA, González-Arenas A. | 04/9/2022 |
| Protein Kinase C-Delta Defect in Autoimmune Lymphoproliferative Syndrome-Like Disease: First Case from the National Iranian Registry and Review of the Literature. | Protein Kinase C-Delta Defect in Autoimmune Lymphoproliferative Syndrome-Like Disease: First Case from the National Iranian Registry and Review of the Literature.
Sharifinejad N, Azizi G, Behniafard N, Zaki-Dizaji M, Jamee M, Yazdani R, Abolhassani H, Aghamohammadi A. | 02/5/2022 |
| Impaired respiratory burst contributes to infections in PKCdelta-deficient patients. | Impaired respiratory burst contributes to infections in PKCδ-deficient patients.
Neehus AL, Moriya K, Nieto-Patlán A, Le Voyer T, Lévy R, Özen A, Karakoc-Aydiner E, Baris S, Yildiran A, Altundag E, Roynard M, Haake K, Migaud M, Dorgham K, Gorochov G, Abel L, Lachmann N, Dogu F, Haskologlu S, İnce E, El-Benna J, Uzel G, Kiykim A, Boztug K, Roderick MR, Shahrooei M, Brogan PA, Abolhassani H, Hancioglu G, Parvaneh N, Belot A, Ikinciogullari A, Casanova JL, Puel A, Bustamante J., Free PMC Article | 11/27/2021 |
| GAK and PRKCD are positive regulators of PRKN-independent mitophagy. | GAK and PRKCD are positive regulators of PRKN-independent mitophagy.
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A., Free PMC Article | 11/22/2021 |
| Phosphorylation of PKCdelta by FER tips the balance from EGFR degradation to recycling. | Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling.
Lonic A, Gehling F, Belle L, Li X, Schieber NL, Nguyen EV, Goodall GJ, Parton RG, Daly RJ, Khew-Goodall Y., Free PMC Article | 09/4/2021 |
| Phosphorylation of protein kinase Cdelta Tyr311 positively regulates thromboxane generation in platelets. | Phosphorylation of protein kinase Cδ Tyr311 positively regulates thromboxane generation in platelets.
Kostyak JC, Mauri B, Patel A, Dangelmaier C, Reddy H, Kunapuli SP., Free PMC Article | 08/21/2021 |
| Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCdelta protein. | Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Yao Y, Liu W, Gajendran B, Wang C, Zacksenhaus E, Sample KM, Varier KM, Hao X, Ben-David Y. | 07/17/2021 |
| The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K(+) channel Kv1.1 through protein kinase C delta. | The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K(+) channel Kv1.1 through protein kinase C delta.
Tian Y, Korn P, Tripathi P, Komnig D, Wiemuth D, Nikouee A, Classen A, Bolm C, Falkenburger BH, Lüscher B, Gründer S., Free PMC Article | 07/10/2021 |