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    ARHGAP15 Rho GTPase activating protein 15 [ Homo sapiens (human) ]

    Gene ID: 55843, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    COLQ and ARHGAP15 are Associated with Diverticular Disease and are Expressed in the Colon.

    COLQ and ARHGAP15 are Associated with Diverticular Disease and are Expressed in the Colon.
    Kline BP, Yochum GS, Brinton DL, Schieffer KM, Weaver T, Harris L, Deiling S, Berg AS, Koltun WA.

    04/16/2022
    ARHGAP15 regulates lung cancer cell proliferation and metastasis via the STAT3 pathway.

    ARHGAP15 regulates lung cancer cell proliferation and metastasis via the STAT3 pathway.
    Liu ZD, Mou ZX, Che XH, Wang K, Li HX, Chen XY, Guo XM.

    10/3/2020
    ARHGAP15 might serve as a tumor suppressor during colorectal cancer progression.

    Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis.
    Pan S, Deng Y, Fu J, Zhang Y, Zhang Z, Ru X, Qin X., Free PMC Article

    12/7/2019
    ARHGAP15 rs4662344-T ssociation with diverticular disease in Iceland and Denmark population.

    Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.
    Sigurdsson S, Alexandersson KF, Sulem P, Feenstra B, Gudmundsdottir S, Halldorsson GH, Olafsson S, Sigurdsson A, Rafnar T, Thorgeirsson T, Sørensen E, Nordholm-Carstensen A, Burcharth J, Andersen J, Jørgensen HS, Possfelt-Møller E, Ullum H, Thorleifsson G, Masson G, Thorsteinsdottir U, Melbye M, Gudbjartsson DF, Stefansson T, Jonsdottir I, Stefansson K., Free PMC Article

    12/22/2018
    ARHGAP15 immunoreactivity correlated with decreased risk of recurrence and improved prognosis in breast carcinoma. ARHGA15 overexpression suppressed cell proliferation and migration of MCF-7 cells.

    ARHGAP15 in Human Breast Carcinoma: A Potent Tumor Suppressor Regulated by Androgens.
    Takagi K, Miki Y, Onodera Y, Ishida T, Watanabe M, Sasano H, Suzuki T., Free PMC Article

    09/1/2018
    FOXP3 can regulate the expression of ARHGAP15 and affects migration of glioma cells through the Rac1 signaling pathway

    Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway.
    Sun Z, Zhang B, Wang C, Fu T, Li L, Wu Q, Cai Y, Wang J., Free PMC Article

    03/11/2017
    ArhGAP15 plays a dual negative role in regulating small GTPase signaling, by acting at the level of the GTPase itself, as well interacting with its effector, Pak kinase.

    ArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signaling.
    Radu M, Rawat SJ, Beeser A, Iliuk A, Tao WA, Chernoff J., Free PMC Article

    11/30/2013
    ARHGAP15 is associated with acute lung injury in mice

    Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1.
    Leikauf GD, Concel VJ, Liu P, Bein K, Berndt A, Ganguly K, Jang AS, Brant KA, Dietsch M, Pope-Varsalona H, Dopico RA Jr, Di YP, Li Q, Vuga LJ, Medvedovic M, Kaminski N, You M, Prows DR., Free PMC Article

    02/14/2011
    Observational study of gene-disease association. (HuGE Navigator)

    Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
    Dick DM, Meyers J, Aliev F, Nurnberger J Jr, Kramer J, Kuperman S, Porjesz B, Tischfield J, Edenberg HJ, Foroud T, Schuckit M, Goate A, Hesselbrock V, Bierut L., Free PMC Article

    06/30/2010
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    a potential regulator of Rac1

    ArhGAP15, a novel human RacGAP protein with GTPase binding property.
    Seoh ML, Ng CH, Yong J, Lim L, Leung T.

    01/21/2010
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