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    RELN reelin [ Homo sapiens (human) ]

    Gene ID: 5649, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion.

    Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion.
    Serafin DS, Harris NR, Bálint L, Douglas ES, Caron KM., Free PMC Article

    09/12/2024
    Exome sequencing in four families with neurodevelopmental disorders: genotype-phenotype correlation and identification of novel disease-causing variants in VPS13B and RELN.

    Exome sequencing in four families with neurodevelopmental disorders: genotype-phenotype correlation and identification of novel disease-causing variants in VPS13B and RELN.
    Afridi TUK, Fatima A, Satti HS, Akram Z, Yousafzai IK, Naeem WB, Fatima N, Ali A, Iqbal Z, Khan A, Shahzad M, Liu C, Toft M, Zhang F, Tariq M, Davis EE, Khan TN.

    08/30/2024
    De novo monoallelic Reelin missense variants cause dominant neuronal migration disorders via a dominant-negative mechanism.

    De novo monoallelic Reelin missense variants cause dominant neuronal migration disorders via a dominant-negative mechanism.
    Riva M, Ferreira S, Hayashi K, Saillour Y, Medvedeva VP, Honda T, Hayashi K, Altersitz C, Albadri S, Rosello M, Dang J, Serafini M, Causeret F, Henry OJ, Roux CJ, Bellesme C, Freri E, Josifova D, Parrini E, Guerrini R, Del Bene F, Nakajima K, Bahi-Buisson N, Pierani A., Free PMC Article

    08/21/2024
    OCRL1 Deficiency Affects the Intracellular Traffic of ApoER2 and Impairs Reelin-Induced Responses.

    OCRL1 Deficiency Affects the Intracellular Traffic of ApoER2 and Impairs Reelin-Induced Responses.
    Fuentealba LM, Pizarro H, Marzolo MP., Free PMC Article

    08/1/2024
    The interaction of RELN-DNMT genes involving in neurotrophin signaling pathway contributes to schizophrenia susceptibility.

    The interaction of RELN-DNMT genes involving in neurotrophin signaling pathway contributes to schizophrenia susceptibility.
    Ping J, Wan J, Luo J, Du B, Liu X, Jiang T, Zhang J.

    04/10/2024
    Reelin through the years: From brain development to inflammation.

    Reelin through the years: From brain development to inflammation.
    Alexander A, Herz J, Calvier L., Free PMC Article

    10/13/2023
    Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency.

    Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency.
    Li Q, Morrill NK, Moerman-Herzog AM, Barger SW, Joly-Amado A, Peters M, Soueidan H, Diemler C, Prabhudeva S, Weeber EJ, Nash KR.

    09/6/2023
    Reelin Plasma Levels Identify Cognitive Decline in Alcohol Use Disorder Patients During Early Abstinence: The Influence of APOE4 Expression.

    Reelin Plasma Levels Identify Cognitive Decline in Alcohol Use Disorder Patients During Early Abstinence: The Influence of APOE4 Expression.
    Escudero B, Moya M, López-Valencia L, Arias F, Orio L., Free PMC Article

    08/31/2023
    Identification and Validation of RELN Mutation as a Response Indicator for Immune Checkpoint Inhibitor Therapy in Melanoma and Non-Small Cell Lung Cancer.

    Identification and Validation of RELN Mutation as a Response Indicator for Immune Checkpoint Inhibitor Therapy in Melanoma and Non-Small Cell Lung Cancer.
    Li Z, Wang X, Yang Y, Shi F, Zhang W, Wang Q, Wang S., Free PMC Article

    12/31/2022
    Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis.

    Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis.
    Bracher-Smith M, Leonenko G, Baker E, Crawford K, Graham AC, Salih DA, Howell BW, Hardy J, Escott-Price V., Free PMC Article

    10/8/2022
    Monoallelic and biallelic mutations in RELN underlie a graded series of neurodevelopmental disorders.

    Monoallelic and biallelic mutations in RELN underlie a graded series of neurodevelopmental disorders.
    Di Donato N, Guerrini R, Billington CJ, Barkovich AJ, Dinkel P, Freri E, Heide M, Gershon ES, Gertler TS, Hopkin RJ, Jacob S, Keedy SK, Kooshavar D, Lockhart PJ, Lohmann DR, Mahmoud IG, Parrini E, Schrock E, Severi G, Timms AE, Webster RI, Willis MJH, Zaki MS, Gleeson JG, Leventer RJ, Dobyns WB., Free PMC Article

    10/1/2022
    SNP-PCR genotyping links alterations in the GABAA receptor (GABRG3: rs208129) and RELN (rs73670) genes to autism spectrum disorder among peadiatric Iraqi Arabs.

    SNP-PCR genotyping links alterations in the GABAA receptor (GABRG3: rs208129) and RELN (rs73670) genes to autism spectrum disorder among peadiatric Iraqi Arabs.
    Ali ZA, Yasseen AA, McAllister KA, Al-Dujailli A, Al-Karaqully AJ, Jumaah AS., Free PMC Article

    07/16/2022
    RELN rs7341475 Associates with Brain Structure in Japanese Healthy Females.

    RELN rs7341475 Associates with Brain Structure in Japanese Healthy Females.
    Yamaguchi R, Matsudaira I, Takeuchi H, Imanishi T, Kimura R, Tomita H, Kawashima R, Taki Y.

    07/2/2022
    The risks of RELN polymorphisms and its expression in the development of otosclerosis.

    The risks of RELN polymorphisms and its expression in the development of otosclerosis.
    Priyadarshi S, Hansdah K, Singh N, Bouzid A, Ray CS, Panda KC, Biswal NC, Desai A, Choudhury JC, Tekari A, Masmoudi S, Ramchander PV., Free PMC Article

    06/11/2022
    Association between CpG island DNA methylation in the promoter region of RELN and positive and negative types of schizophrenia.

    Association between CpG island DNA methylation in the promoter region of RELN and positive and negative types of schizophrenia.
    Zhou J, Zhou D, Yan T, Chen W, Xie H, Xiong Y., Free PMC Article

    06/11/2022
    Identification of putative genetic variants in major depressive disorder patients in Pakistan.

    Identification of putative genetic variants in major depressive disorder patients in Pakistan.
    Qazi SR, Irfan M, Ramzan Z, Jahanzaib M, Khan MZ, Nasir M, Shakeel M, Khan IA.

    04/9/2022
    Mice with exonic RELN deletion identified from a patient with schizophrenia have impaired visual discrimination learning and reversal learning in touchscreen operant tasks.

    Mice with exonic RELN deletion identified from a patient with schizophrenia have impaired visual discrimination learning and reversal learning in touchscreen operant tasks.
    Liao J, Dong G, Wulaer B, Sawahata M, Mizoguchi H, Mori D, Ozaki N, Nabeshima T, Nagai T, Yamada K.

    03/19/2022
    The structure-function relationship of a signaling-competent, dimeric Reelin fragment.

    The structure-function relationship of a signaling-competent, dimeric Reelin fragment.
    Turk LS, Kuang X, Dal Pozzo V, Patel K, Chen M, Huynh K, Currie MJ, Mitchell D, Dobson RCJ, D'Arcangelo G, Dai W, Comoletti D.

    03/19/2022
    New Strategies for the Treatment of Neuropsychiatric Disorders Based on Reelin Dysfunction.

    New Strategies for the Treatment of Neuropsychiatric Disorders Based on Reelin Dysfunction.
    Tsuneura Y, Nakai T, Mizoguchi H, Yamada K., Free PMC Article

    03/12/2022
    The hsa_circRNA_102049 mediates the sorafenib sensitivity of hepatocellular carcinoma cells by regulating Reelin gene expression.

    The hsa_circRNA_102049 mediates the sorafenib sensitivity of hepatocellular carcinoma cells by regulating Reelin gene expression.
    Wang S, Liu D, Wei H, Hua Y, Shi G, Qiao J., Free PMC Article

    02/26/2022
    Correlation of Four Single Nucleotide Polymorphisms of the RELN Gene With Schizophrenia.

    Correlation of Four Single Nucleotide Polymorphisms of the RELN Gene With Schizophrenia.
    Ping J, Zhang J, Wan J, Banerjee A, Huang C, Yu J, Jiang T, Du B.

    01/15/2022
    The depletion of Circ-PRKDC enhances autophagy and apoptosis in T-cell acute lymphoblastic leukemia via microRNA-653-5p/Reelin mediation of the PI3K/AKT/mTOR signaling pathway.

    The depletion of Circ-PRKDC enhances autophagy and apoptosis in T-cell acute lymphoblastic leukemia via microRNA-653-5p/Reelin mediation of the PI3K/AKT/mTOR signaling pathway.
    Ling Z, Fang ZG, Wu JY, Liu JJ.

    01/8/2022
    Association Between REELIN Gene Polymorphisms (rs7341475 and rs262355) and Risk of Schizophrenia: an Updated Meta-analysis.

    Association Between REELIN Gene Polymorphisms (rs7341475 and rs262355) and Risk of Schizophrenia: an Updated Meta-analysis.
    Marzan S, Aziz MA, Islam MS.

    10/30/2021
    A pilot proteomic study with a prospective cohort suspected to develop preeclampsia.

    A pilot proteomic study with a prospective cohort suspected to develop preeclampsia.
    Liu J, Liu X, Zhao S, Zheng Y, Chen L, Wang J, Zhan S, Hu S, Dong Y, Tang G, Lu Y, Zhai Y, Cao Z.

    10/16/2021
    Downregulation of reelin predicts poor prognosis for glioma.

    Downregulation of reelin predicts poor prognosis for glioma.
    Li X, Fan W, Yao A, Song H, Ge Y, Yan M, Shan Y, Zhang C, Li P, Jia L.

    09/11/2021
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