| MiR-5189-3p Suppresses cell Proliferation, Invasion and Migration Through Targeting EIF5A2 in Laryngeal Squamous Cell Carcinoma. | MiR-5189-3p Suppresses cell Proliferation, Invasion and Migration Through Targeting EIF5A2 in Laryngeal Squamous Cell Carcinoma.
Lou D, Jia Q, Zhang H, Wang J, Liu L, Liu Z, Jia X, Wang J, Shan C. | 07/5/2024 |
| Long non-coding RNA RAD51-AS1 promotes the tumorigenesis of ovarian cancer by elevating EIF5A2 expression. | Long non-coding RNA RAD51-AS1 promotes the tumorigenesis of ovarian cancer by elevating EIF5A2 expression.
Zhao L, Huang J, Liu W, Su X, Zhao B, Wang X, He X., Free PMC Article | 04/12/2024 |
| microRNA-15a-5p suppresses hypoxia-induced tumor growth and chemoresistance in bladder cancer by binding to eIF5A2. | microRNA-15a-5p suppresses hypoxia-induced tumor growth and chemoresistance in bladder cancer by binding to eIF5A2.
Yang J, Xiang H, Cheng M, Jiang X, Chen Y, Zheng L, Yan S, Zhang S, Zhang C, Chen W, Chen D. | 03/21/2024 |
| EIF5A2 Promotes Doxorubicin Resistance in Bladder Cancer Cells through the TGF-beta Signaling Pathway. | EIF5A2 Promotes Doxorubicin Resistance in Bladder Cancer Cells through the TGF-β Signaling Pathway.
Yang J, Jiang X, Chen Y, Teng L. | 12/18/2023 |
| MicroRNA-577/EIF5A2 axis suppressed the proliferation of DDP-resistant nasopharyngeal carcinoma cells by blocking TGF-beta signaling pathway. | MicroRNA-577/EIF5A2 axis suppressed the proliferation of DDP-resistant nasopharyngeal carcinoma cells by blocking TGF-β signaling pathway.
Wu R, Zhong Q, Liu H, Liu S. | 09/14/2023 |
| EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells. | EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cells.
Liu Y, Peng L, Chen J, Chen L, Wu Y, Cheng M, Chen M, Ye X, Jin Y., Free PMC Article | 02/13/2023 |
| EIF5A2 promotes proliferation and invasion of intrahepatic cholangiocarcinoma cells. | EIF5A2 promotes proliferation and invasion of intrahepatic cholangiocarcinoma cells.
Yang SH, Hu S, Kang Q, Liu LX, Wei Q, Song ZM, Chen YH, Liao ZJ, Huan YF, Wang XJ, Zou H, Zhang XW. | 08/27/2022 |
| Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes. | Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes.
Farache D, Liu L, Lee ASY. | 05/21/2022 |
| HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer. | HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
Zhang Z, He G, Lv Y, Liu Y, Niu Z, Feng Q, Hu R, Xu J., Free PMC Article | 04/16/2022 |
| The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2. | The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2.
Zhuang S, Xie J, Zhen J, Guo L, Hong Z, Li F, Xu D. | 03/26/2022 |
| Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway. | Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway.
Li X, He J, Ren X, Zhao H, Zhao H., Free PMC Article | 10/2/2021 |
| EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis. | EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis.
Wang K, Wang Y, Wang Y, Liu S, Wang C, Zhang S, Zhang T, Yang X., Free PMC Article | 08/28/2021 |
| Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy. | Knockdown of eukaryotic translation initiation factor 5A2 enhances the therapeutic efficiency of doxorubicin in hepatocellular carcinoma cells by triggering lethal autophagy.
Tang Y, Chen K, Luan X, Zhang J, Liu R, Zheng X, Xie S, Ke H, Zhang X, Chen W., Free PMC Article | 08/7/2021 |
| MicroRNA-33b regulates sensitivity to daunorubicin in acute myelocytic leukemia by regulating eukaryotic translation initiation factor 5A-2. | MicroRNA-33b regulates sensitivity to daunorubicin in acute myelocytic leukemia by regulating eukaryotic translation initiation factor 5A-2.
Liu Y, Lei P, Qiao H, Sun K, Lu X, Bao F, Yu R, Lian C, Li Y, Chen W, Xue F. | 02/27/2021 |
| Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis. | Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis.
Luan W, Ding Y, Yuan H, Ma S, Ruan H, Wang J, Lu F, Bu X., Free PMC Article | 02/6/2021 |
| MicroRNA-588 regulates migration capacity and invasiveness of renal cancer cells by targeting EIF5A2. | MicroRNA-588 regulates migration capacity and invasiveness of renal cancer cells by targeting EIF5A2.
Dong JS, Wu B, Zha ZL. | 11/21/2020 |
| MicroRNA-383 inhibits doxorubicin resistance in hepatocellular carcinoma by targeting eukaryotic translation initiation factor 5A2. | MicroRNA-383 inhibits doxorubicin resistance in hepatocellular carcinoma by targeting eukaryotic translation initiation factor 5A2.
Tu C, Chen W, Wang S, Tan W, Guo J, Shao C, Wang W., Free PMC Article | 09/19/2020 |
| DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFbeta/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53 | DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53.
Güth R, Adamian Y, Geller C, Molnar J, Maddela J, Kutscher L, Bhakta K, Meade K, Kim SL, Agajanian M, Kelber JA., Free PMC Article | 06/27/2020 |
| High EIF5A2 expression is associated with renal interstitial fibrosis. | The long noncoding RNA myocardial infarction-associated transcript modulates the epithelial-mesenchymal transition in renal interstitial fibrosis.
Wang Z, Zhang B, Chen Z, He Y, Ru F, Liu P, Chen X. | 01/25/2020 |
| In cohort of patients with upper urinary tract urothelial carcinoma EIF5A2 low expression group had significantly longer overall survival (OS) and progression-free survival (PFS) than the EIF5A2 high expression group. The high expression of EIF5A2 significantly predict poor OS and PFS in the subset patients. EIF5A2 was an independent prognostic factor for OS and PFS. | Overexpression of EIF5A2 in upper urinary tract urothelial carcinoma is a new independent prognostic marker of survival.
Fang Y, Cen JJ, Cao JZ, Huang Y, Feng ZH, Lu J, Wei JH, Chen ZH, Liang YP, Liao B, Luo JH, Chen W. | 01/11/2020 |
| the tumor suppressive role of miR-221-3p in MB cell proliferation at least in part via targeting EIF5A2 | Downregulation of EIF5A2 by miR-221-3p inhibits cell proliferation, promotes cell cycle arrest and apoptosis in medulloblastoma cells.
Yang Y, Cui H, Wang X. | 03/16/2019 |
| EIF5A2 as a direct and functional target of miR-203. | MiRNA-203 suppresses cell proliferation, migration and invasion in colorectal cancer via targeting of EIF5A2.
Deng B, Wang B, Fang J, Zhu X, Cao Z, Lin Q, Zhou L, Sun X., Free PMC Article | 04/28/2018 |
| The model had 92% sensitivity and 92% specificity. We obtained similar results in the independent validation cohort. AIB1 and EIF5A2 show promise for the noninvasive detection of bladder cancer. The model based on AIB1, EIF5A2, and NMP22 outperformed each of the three individual biomarkers for detecting Bladder cancer. | Identification and validation of AIB1 and EIF5A2 for noninvasive detection of bladder cancer in urine samples.
Zhou BF, Wei JH, Chen ZH, Dong P, Lai YR, Fang Y, Jiang HM, Lu J, Zhou FJ, Xie D, Luo JH, Chen W., Free PMC Article | 01/20/2018 |
| Data suggest that inhibition of eIF5A2 alters progression of the EMT to decrease the invasion and metastasis of HCC cells via ROS-related pathways. | Eukaryotic translation initiation factor 5A2 regulates the migration and invasion of hepatocellular carcinoma cells via pathways involving reactive oxygen species.
Liu RR, Lv YS, Tang YX, Wang YF, Chen XL, Zheng XX, Xie SZ, Cai Y, Yu J, Zhang XN., Free PMC Article | 12/9/2017 |
| EIF5A2 overexpression may contribute to cancer progression and poor prognosis. Therefore, EIF5A2 could be a novel potential prognostic marker for Federation of Gynecology and Obstetrics (FIGO) stage I-II cervical cancer. | Overexpression of eukaryotic initiation factor 5A2 (EIF5A2) is associated with cancer progression and poor prognosis in patients with early-stage cervical cancer.
Yang SS, Gao Y, Wang DY, Xia BR, Liu YD, Qin Y, Ning XM, Li GY, Hao LX, Xiao M, Zhang YY. | 10/21/2017 |