Pan-caner analysis identifies PSMA7 as a targets for amplification at 20q13.33 in tumorigenesis. | Pan-caner analysis identifies PSMA7 as a targets for amplification at 20q13.33 in tumorigenesis. Sheng G, Li F, Jin W, Wang K., Free PMC Article | 02/14/2024 |
Proteasome Subunit Alpha Type-7 Expression Suppresses Cutaneous Squamous Cell Carcinoma Progression by Inhibiting Cancer-associated Cytokines. | Proteasome Subunit Alpha Type-7 Expression Suppresses Cutaneous Squamous Cell Carcinoma Progression by Inhibiting Cancer-associated Cytokines. Xu X, Pei M, Kim KY, Xi H, Lee SG, Chung KY, Roh MR, Jin Z., Free PMC Article | 06/30/2023 |
Proteasome Subunit Alpha Type 7 Promotes Proliferation and Metastasis of Gastric Cancer Through MAPK Signaling Pathway. | Proteasome Subunit Alpha Type 7 Promotes Proliferation and Metastasis of Gastric Cancer Through MAPK Signaling Pathway. Xia S, Ji L, Tang L, Zhang L, Zhang X, Tang Q, Feng Z, Lu L. | 04/30/2022 |
Deubiquitinase UCHL1 Maintains Protein Homeostasis through the PSMA7-APEH-Proteasome Axis in High-grade Serous Ovarian Carcinoma. | Deubiquitinase UCHL1 Maintains Protein Homeostasis through the PSMA7-APEH-Proteasome Axis in High-grade Serous Ovarian Carcinoma. Tangri A, Lighty K, Loganathan J, Mesmar F, Podicheti R, Zhang C, Iwanicki M, Drapkin R, Nakshatri H, Mitra S. | 01/29/2022 |
PSMA7 silencing can suppress cervical cancer cell proliferation and VEGF expression in addition to promoting cell apoptosis through inhibiting the UPP signaling pathway. | Effects of shRNA-mediated silencing of PSMA7 on cell proliferation and vascular endothelial growth factor expression via the ubiquitin-proteasome pathway in cervical cancer. Ren CC, Yang L, Liu L, Chen YN, Cheng GM, Zhang XA, Liu H. | 04/4/2020 |
Serum anti-PSMA7 antibodies were elevated in sera from amyotrophic lateral sclerosis patients. | Novel autoantibodies against the proteasome subunit PSMA7 in amyotrophic lateral sclerosis. Sugimoto K, Hiwasa T, Shibuya K, Hirano S, Beppu M, Isose S, Arai K, Takiguchi M, Kuwabara S, Mori M. | 10/5/2019 |
PPSMA 7 is overexpressed in gastric cancer tissues | [Expression of PSMA 7 and its effect on proliferation, invasion, migration and tumorigenesis of gastric cancer]. Xia S, Zhang L, Cheng F, Feng Z, Lu L., Free PMC Article | 08/24/2019 |
salivary exosomal PSMA7 was present at high levels in salivary exosomes from subjects with Inflammatory bowel disease. It can be a very promising biomarker | Salivary exosomal PSMA7: a promising biomarker of inflammatory bowel disease. Zheng X, Chen F, Zhang Q, Liu Y, You P, Sun S, Lin J, Chen N., Free PMC Article | 12/30/2017 |
Data indicate that proteasome subunit alpha 6 (PSMA6) direct contacts with proteasome subunit alpha 7 (PSMA7) tetradecamer. | Disassembly of the self-assembled, double-ring structure of proteasome α7 homo-tetradecamer by α6. Ishii K, Noda M, Yagi H, Thammaporn R, Seetaha S, Satoh T, Kato K, Uchiyama S., Free PMC Article | 11/5/2016 |
Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit 9 (PSMD9), proteasome alpha type 7 subunit (PSMA7) and PSMD13 genes. | Proteasome system dysregulation and treatment resistance mechanisms in major depressive disorder. Minelli A, Magri C, Barbon A, Bonvicini C, Segala M, Congiu C, Bignotti S, Milanesi E, Trabucchi L, Cattane N, Bortolomasi M, Gennarelli M., Free PMC Article | 07/30/2016 |
c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit | c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit. Li D, Dong Q, Tao Q, Gu J, Cui Y, Jiang X, Yuan J, Li W, Xu R, Jin Y, Li P, Weaver DT, Ma Q, Liu X, Cao C. | 01/30/2016 |
PSMA7 functions partially through downregulation NOD1. | PSMA7 directly interacts with NOD1 and regulates its function. Yang L, Tang Z, Zhang H, Kou W, Lu Z, Li X, Li Q, Miao Z. | 02/22/2014 |
PSMA7 inhibits the proliferation, tumorigenicity and invasion of A549 cells in vitro | PSMA7 inhibits the tumorigenicity of A549 human lung adenocarcinoma cells. Tan JY, Huang X, Luo YL. | 10/13/2012 |
CNB binds to proteasome subunit alpha type 7 (PSMA7) and inhibits the transactivation activity of hypoxia-inducible factor-1alpha (HIF-1alpha) via the proteasome pathway. | Calcineurin B subunit interacts with proteasome subunit alpha type 7 and represses hypoxia-inducible factor-1α activity via the proteasome pathway. Li N, Zhang Z, Zhang W, Wei Q. | 04/9/2011 |
High expression of PSMA7 was significantly correlated with liver metastasis. | [High expression of proteasome subunit PSMA7 in colorectal cancer is significantly correlated with liver metastasis]. Hu XT, Chen W, Wang D, Shi QL, Zhang FB, Liao YQ, Jin M, He C. | 04/12/2010 |
cell surface binding of EMAP-II results in its internalization into the cytoplasmic compartment where it interacts with PSMA7, a component of the proteasome degradation pathway. This interaction increases HIF-1alpha degradation under hypoxic conditions. | Endothelial monocyte activating polypeptide-II modulates endothelial cell responses by degrading hypoxia-inducible factor-1alpha through interaction with PSMA7, a component of the proteasome. Tandle AT, Calvani M, Uranchimeg B, Zahavi D, Melillo G, Libutti SK. | 01/21/2010 |
PSMA7 may play an important role in colorectal cancer progression. | The proteasome subunit PSMA7 located on the 20q13 amplicon is overexpressed and associated with liver metastasis in colorectal cancer. Hu XT, Chen W, Wang D, Shi QL, Zhang FB, Liao YQ, Jin M, He C. | 01/21/2010 |
Unexpected interaction between alpha4 and alpha7 subunits may provide a molecular basis for the formation of previously reported 13S and 16S assembly intermediates. | The alpha4 and alpha7 subunits and assembly of the 20S proteasome. Apcher GS, Maitland J, Dawson S, Sheppard P, Mayer RJ. | 01/21/2010 |
The present study demonstrates that c-Abl and Arg (abl-related gene) tyrosine kinases associate with and phosphorylate the proteasome PSMA7 (alpha4) subunit at Tyr-153. | Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation. Liu X, Huang W, Li C, Li P, Yuan J, Li X, Qiu XB, Ma Q, Cao C. | 01/21/2010 |