Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1. | Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1. Munipalli SB, Yenugu S. | 12/5/2023 |
Biallelic variants in PSMB1 encoding the proteasome subunit beta6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. | Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE. | 08/7/2021 |
Collectively, our study demonstrates PSMB1 is an important regulator of innate immune signaling in viral infection | PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε. Wu F, Niu Z, Zhou B, Li P, Qian F., Free PMC Article | 06/22/2019 |
In vitro analyses demonstrated significantly reduced protease activity in proteasomes of individuals with G/G genotype compared with that of C/C carriers, despite that PSMB1 expression and proteasome assembly remained unaltered. | Proteasome Subunit Beta Type 1 P11A Polymorphism Is a New Prognostic Marker in Multiple Myeloma. Varga G, Mikala G, Kiss KP, Kosóczki É, Szabó E, Meggyesi N, Balassa K, Kövy P, Tegze B, Szombath G, Tordai A, Andrikovics H, Homolya L, Masszi T. | 07/7/2018 |
The proteasome beta1 subunit plays a novel role in tumorigenesis by degrading p27Kip1. | A novel role of proteasomal β1 subunit in tumorigenesis. Yuan F, Ma Y, You P, Lin W, Lu H, Yu Y, Wang X, Jiang J, Yang P, Ma Q, Tao T., Free PMC Article | 04/26/2014 |
The mutated form of PSMB1 displayed increased nuclear translocation, resulting in activation of transcription in adipocytes. | Role of nuclear localization of PSMB1 in transcriptional activation. Yamauchi J, Sekiguchi M, Shirai T, Yamada M, Ishimi Y. | 04/5/2014 |
The proteasome was found to be activated in primary sjogren syndrome, with upregulation of gene expression of catalytic proteasome subunits. | Gene expression of catalytic proteasome subunits and resistance toward proteasome inhibition of B lymphocytes from patients with primary sjogren syndrome. Martinez-Gamboa L, Lesemann K, Kuckelkorn U, Scheffler S, Ghannam K, Hahne M, Gaber-Elsner T, Egerer K, Naumann L, Buttgereit F, Dörner T, Kloetzel PM, Burmester GR, Faustman DL, Feist E. | 12/14/2013 |
Follicular lymphoma patients with PSMB1 P11A (G allele) and low CD68 expression have significantly longer progression free survival with bortezomib-rituximab versus rituximab. | Prespecified candidate biomarkers identify follicular lymphoma patients who achieved longer progression-free survival with bortezomib-rituximab versus rituximab. Coiffier B, Li W, Henitz ED, Karkera JD, Favis R, Gaffney D, Shapiro A, Theocharous P, Elsayed YA, van de Velde H, Schaffer ME, Osmanov EA, Hong X, Scheliga A, Mayer J, Offner F, Rule S, Teixeira A, Romejko-Jarosinska J, de Vos S, Crump M, Shpilberg O, Zinzani PL, Cakana A, Esseltine DL, Mulligan G, Ricci D. | 11/16/2013 |
PSMB1 is part of the transcriptional machinery required for gastrin stimulated expression of PAI-2 and Reg1. | The role of proteasome beta subunits in gastrin-mediated transcription of plasminogen activator inhibitor-2 and regenerating protein1. O'Hara A, Howarth A, Varro A, Dimaline R., Free PMC Article | 09/21/2013 |
Expression of 26S proteasome beta(1)-subunit in NB4 cells increased after incubation with As(2)O(3). | [Influence of As(2)O(3) on proteasome beta(1)-subunit in NB4 cells]. Lü XH, Chen Y, Zhang M, He PC, Wang HY, Ni ZF, Lu R. | 08/27/2011 |
data defined a unique motif of BCL-3 that is needed for its recruitment to the proteasome and identified PSMB1 as a key protein required for the proteasome-mediated degradation of a nuclear and oncogenic IkappaB protein. | BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1. Keutgens A, Zhang X, Shostak K, Robert I, Olivier S, Vanderplasschen A, Chapelle JP, Viatour P, Merville MP, Bex F, Gothot A, Chariot A., Free PMC Article | 09/6/2010 |
Observational study of gene-disease association. (HuGE Navigator) | Evaluation of IDDM8 susceptibility locus in a Russian simplex family data set. Chistiakov DA, Seryogin YA, Turakulov RI, Savost'anov KV, Titovich EV, Zilberman LI, Kuraeva TL, Dedov II, Nosikov VV. | 03/13/2008 |